5IFE,5SYB,7ABI,6G90


Conserved Protein Domain Family
PHF5
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pfam03660: PHF5 (This model is not part of the current CDD release)
PHF5-like protein
This family of proteins the superfamily of PHD-finger proteins. At least one example, from mouse, may act as a chromatin-associated protein. The S. pombe ini1 gene is essential, required for splicing. It is localised in the nucleus, but not detected in the nucleolus and can be complemented by human ini1.
Links
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Statistics
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PSSM-Id: 515726
Aligned: 40 rows
Threshold Bit Score: 125.023
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5IFE_D        17 DLIFCRKQAGVAIGRLCEKCDGKCVICDSYV-----RPCTLVRICDECNYGSY--QGRCVICG-G-PGVSDAYYCKECTI 87  human
Q75DC3         7 DLVMCMKLPGTSIGRLCERCDGKCPSCDSNV-----RPLSKVRICDQCSFGGQ--GKKCILCG-S-IGVSDAYYCWECCK 77  Eremothecium go...
XP_003683844   7 DLVMCMRQPGTHIGMVCDKCDGKCPICDSYV-----RPKSKVRICEQCSFGNT--KTYCIICG-L-PGTSEAYYCWECCK 77 
Q6FMH2         7 DLMMCMNPAGINTGILCEKCDGRCPSCDSYV-----RPRSRVTVCDQCSFGKQ--ATQCILCG-StNGKVPAYYCWECCK 78  [Candida] glabrata
Q06835         7 DLIMCLKQPGVQTGLLCEKCDGKCPICDSYV-----RPKRKVRVCENCSFGKQ--AKNCIICN-LnVGVNDAFYCWECCR 78  Saccharomyces c...
XP_003958614   7 DLVMCMKQPGTQIGLLCDKCDGKCPICDSFIddntiRLKKRVRICQTCSFGKQ--SYSCITCG-SnLAHHEAFYCFECCK 83 
XP_002492808   7 DLVQCFKQPGTTIARLCDKCDGRCPSCDSYV-----NQAELAYICDECSFVSNkgEGKCILCG-S-KSTTDAYYCSECVM 79 
XP_001329047   5 DSIKCGGRPGPEFGLVCEACEGRCPICNAPVk---eDRCVPVHICGECSFGQL--RDKCIVCS-A-PAKYKAYYCEQCSL 77 
XP_818591      8 EQQMCRKMPGASFGYVCDQHDGRCVICDLQFde-vlPSMREVHVCDDCGFGKEg-EERCIMCN-SgKTTEVAYYCHYCVA 84 
6G90_S         7 DLIMCLKQPGVQTGLLCEKCDGKCPICDSYV-----RPKRKVRVCENCSFGKQ--AKNCIICNlN-VGVNDAFYCWECCR 78  brewer's yeast

5IFE_D        88 QEKDRDGCPKIVNLGSSKTDLFYERKK 114 human
Q75DC3        78 LEKDRDGCPRILNVGSNKTDRHFDRKL 104 Eremothecium gossypii
XP_003683844  78 LEKHRDGCPRIINIGSNKVDKYFENKN 104
Q6FMH2        79 LGKNRKGCPRIINIGSNKMDRYFGTKK 105 [Candida] glabrata
Q06835        79 LGKDKDGCPRILNLGSNRLDRHFEKKK 105 Saccharomyces cerevisiae S288C
XP_003958614  84 LEKDKDGCPRIINVGSNTVDKHFLNk- 109
XP_002492808  80 TEKDRDGCPRILNIGTTRSDLFYEKRK 106
XP_001329047  78 LGKDRDGCPRIINVGINRSDRFYERKR 104
XP_818591     85 LEKDRDGCPRVLN--QSRHQRMATLrt 109
6G90_S        79 LGKDKDGCPRILNLGSNRLDRHFEKKK 105 brewer's yeast
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