Conserved Protein Domain Family
SASA

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pfam03629: SASA 
Carbohydrate esterase, sialic acid-specific acetylesterase
The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665.
Statistics
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PSSM-Id: 397610
Aligned: 77 rows
Threshold Bit Score: 215.509
Threshold Setting Gi: 407204304
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CDH50429                   58 VGDVWVMSGQSNMRG-NGFYEDpwtdpPTSYLDHVNnNIHLFQCNET-WTLAQEPT--HRLdQSIrqvNhnlsdpsvkdp 133 Li...
EKE74285                    6 PSDLILMAGQSNMAGhKVGVDD------LAETERGLiEGARIWANGA-W----VPL--AVD-AGY---Q----------- 57  Ce...
WP_013994834               28 PVKVFILGGQSNMDG-TGKSED-----LPEKYRSHPdEVMIWDNKKEkWVSLGTDS--FSE-------R----------- 81  Zo...
WP_013769139               40 KVWVFLLAGQSNMAG-RGLVEA-------QDTVSDP-RIFSINAQAE-VIVAKEPL--H---FYE---P----------- 90  Ha...
jgi:Emtol_1023             44 KLWVFVMAGQSNMAG-RGQVE-------PNDTITNS-RILTINKQGD-LIYAKEPL--HFY-E-----P----------- 94  Em...
WP_012162676               56 KMSLYVLAGQSNMTG-RGPLDA-------ESSKTHP-QVFVFGNDYR-WHLAKDPLd-SID-GQVdpvS----------- 112 Ac...
WGS:ACTP:HMPREF0994_03506 120 VGNLFLIAGQSNSAG-YGK----------DYCTDPPhLCVHLFRNRNqWDLASHPM--NES-TAAgslP----------- 174 La...
WP_009324801              123 VGDVFVIAGQSNAAG-RAKN---------PVADDPElGVHVLRTSAR-WELATHPL--GET-TNAlhvGhye-------- 180 Su...
CDC71334                  106 VGDVFVIAGQSNSAG-FSKT---------PGCREPAaGIHMFRNRCR-WDIASDPM--NEK-TDTahpE----------- 160 Fi...
WP_009508720               97 VGDVWLLAGQSNMEG-CGRMDG-------GAARPHP-LVRAFSMRRE-WRQAADPLhlRMEsPDSchnDgaqh----tre 162 Op...
CDH50429                  134 Kyh-----lWRGFSLGTSFATEYRKhmn-nvPVGLIATAHGGTTLdE--WSpSl-mEnttdpyNnTLYG--AMLARLRKQ 202 Li...
EKE74285                   58 K---------RGFGPELSFARQWQvqt--grPLSIVKLAKGGSYL-SrgWS-AegrG------G-PLYQ--RLVAEVRAA 115 Ce...
WP_013994834               82 R--------KFKFGPEIAFSHLMAKkfp-nhTIAIVKTSGGGTKL-WkhWL-P---G------Q-PMYT--RFLKNMDNA 138 Zo...
WP_013769139               91 G--------RAGLDCGLSFGKALLKgvpkkvSILLLPTAVGGSAM-Rq-WL-----G------D-STYR---EVKLWSNF 145 Ha...
jgi:Emtol_1023             95 T--------RTGLDCGLSFANNLLKniphdvSILLIPTAVGGSAI-Gq-WL-----G------D-STYRdvKLLTNFKEK 152 Em...
WP_012162676              113 Qeg-----kAPGVGPGMTFASALLKhdk-daVIGLIPCARGGSTI-Qe-WQ-Rnl-------sEnSLYG--SCLKRLRAA 174 Ac...
WGS:ACTP:HMPREF0994_03506 175 Nee----mgIPGVSPYLSFGKKYYelt--gmPVGLIQTAQGGSSI-Er-WN-P---K------DgDLYG--NMMNKIRET 234 La...
WP_009324801              181 -------nhNPGHSPWLHFAKRLKrel--gyPIGLVPCAYGGAPLr--wWNpee--------ngaLFTN--MLEMLADYD 239 Su...
CDC71334                  161 Nae----lfLPGQSPWLAFALALKrel--gyPIGLIQTSVGGSPL-Sa-WN-PeenG--------ILFR--NMIRTVSMC 221 Fi...
WP_009508720              163 QaenarrtaQRGVGAGVFFAREMLars--gvPQGLVCIAHGGTSMeQ--WN-----PvhkksgGaSQYG--SMLLSLRAT 231 Op...
CDH50429                  203 EN---------QVAGILWYQGESDAEKT-ENA------ENYKDKFEKFITTTRERLDANQLPFLFVQI-AR------Qiq 259 Li...
EKE74285                  116 MAtg-----pvRLRGLIWMQGESDALDH-EDA------QAYGTRFEGFVARLRQDLGVPDLPI-VAGL-IT--------- 172 Ce...
WP_013994834              139 LQnlkgqgvayEVSGMLWMQGESDAETL-EWA------NAYEENLKVLYKDVRKETGKKNLPIVMGRI-SIgllrktPw- 209 Zo...
WP_013769139              146 LEkvalgkkhgRIKAVLWHQGESDA-ND-KNI------PLYPENLARLLQNFRRAVGSPQLPVLMGEL-GA------Fs- 209 Ha...
jgi:Emtol_1023            153 VAigm---kygIVRGILWHQGESDASPK-RIA-------VHEENLKSLFGTFRKTVGNSKLPIILGEL-GS------Ys- 213 Em...
WP_012162676              175 SLm-------gQLEGMLFFQGEADALDQkQFShlslspQQWSKKFEKFIESFRLDTKQENLPIVFAQI-GS--------- 237 Ac...
WGS:ACTP:HMPREF0994_03506 235 KG---------RYAGVLWYQGCED-TRP-EQA------EAYGEHFRELAEALRAALGY-EIPFFTMQL-NR------Fi- 288 La...
WP_009324801              240 I----------HPRAVLWYQGEAE-GYE-DSA------QTYLERFAVFVRHTRAALGQPELPFLTVQLnRCmegpseK-- 299 Su...
CDC71334                  222 GG---------RVKGVLWYQGETDAGGE-TET------AGYLERFAGFVSAVRREMNDPLLPFFTVQL-NKflsctdPd- 283 Fi...
WP_009508720              232 GQ---------PCAGVLWYQGESDTAAP-LAA-------VYTDRMKKLVAATRRDLHQPDLPWIIVQL-ARvf------- 286 Op...
CDH50429                  260 ggQDIdnEWSMIRDAq-RLvNDdyDPKRVGAVTTIDLP-MDDRIHLSAVGQKRVGQRLARAAAN 321 Lichtheimia corymb...
EKE74285                  173 ---APggHVDLVRDAmaSA-----DVTAFKTVETRDLAhRSGAVHLTASGLAALGQRFADALSS 228 Celeribacter baekd...
WP_013994834              210 --NFD--HTEVVQAA--QD-KVaaEDKNVFIINTDKLEtLNDNTHFNSESNIWLGEKMGKLMWK 266 Zobellia galactani...
WP_013769139              210 --QNPqqWQKINQLI--NAhAA--KDPFTTVISTQDLQhKGDKIHFNSAGQRLLGQRFAEAYLQ 267 Haliscomenobacter ...
jgi:Emtol_1023            214 --KTNaeWQQINQQL--RTyVL--SDKNSTIIQTQDLKhKGDDIHFDAAGQRTIGERFALAFIQ 271 Emticicia oligotro...
WP_012162676              238 --HDApnLLTQWNVVkkQQeNI--QLPHVAMITTDDLA-LEDYVHYTTKSYRTIGQRFANAYIK 296 Acaryochloris marina
WGS:ACTP:HMPREF0994_03506 289 --NGP--FDEAWGMVreAQrRAalSIPAVFVLPTTNLS-LSDSVHNSAQANVALGIRLARQCAC 347 Lachnospiraceae ba...
WP_009324801              300 --LDR--QWGMVREAqrQAwHT---LEHVTVVPAADLAlYDFI-HNASEGNLVVGERCARAALA 355 Subdoligranulum sp...
CDC71334                  284 --TDR--RFAEIREAqrKAgKI----PGVTVIPSLDLT-LSDEIHNNSASNNALGERIAFTALG 338 Firmicutes bacteri...
WP_009508720              287 ghRSEtgWNSVQEQQ--RLlPA--KIRNLATVAAIDLAlDDPI-HISATAFPRLAARLARAADR 345 Opitutaceae bacter...
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