5ZOV


Conserved Protein Domain Family
EIIC-GAT

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pfam03611: EIIC-GAT 
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PTS system sugar-specific permease component
This family includes bacterial transmembrane proteins with a putative sugar-specific permease function, including and analogous to the IIC component of the PTS system. It has been suggested that this permease may form part of an L-ascorbate utilisation pathway, with proposed specificity for 3-keto-L-gulonate (formed by hydrolysis of L-ascorbate). This family includes the IIC component of the galactitol specific GAT family PTS system.
Statistics
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PSSM-Id: 397599
Aligned: 115 rows
Threshold Bit Score: 163.084
Threshold Setting Gi: 81436877
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5ZOV_A           14 QVLS--KAPFLLGIVACIGYILLKKDTTTVIKGTIKTIVGFMIVQAGSGFLVANFKPIIEGLSKY----HNLt------G 81  Pasteurella ...
wugsc:KPN_03550   8 YILDl-GPTVMLPIVIIIFSKLLGMKLGDCFKSGLHIGIGFVGIGLVIGLMLDSIGPAAKAMAEH----FQInlhvidiG 82  Klebsiella p...
jgi:Sterm_3385   14 YILDl-GPAVMLPLVIIIFALCLGLKLGKAFNAGLMIGIGFIGIGIVITLMRDTLGPAAEQMAQN----FGLnltvidlG 88  Sebaldella t...
WP_006565684      6 TILGl-GASVIMPIVIFLLGVVFRMKVKNALRAGLTVGIGFTGISLAISLVSDNLGGLVKAMQAN----WGLalditdvG 80  Anaerostipes
WP_009291131      7 LFFDtfGNYITVPIIIFIICLIFKAPVKKAFMSAVLIGVGLKGMAFITSAFGSVLSALVTKLIEQ----TGInlpaldvG 82  Anaerostipes
WP_012862968      8 SIFDtfGPAIFVPAVLFIIALIMKVNVKKAFNSALLAGVGLTGFNMLIGAYIPVIVPTVQKMVDI----TGInlpvidtG 83  Sebaldella t...
WP_006568142     10 AIIDnfGSAIIVPFIIFIIALIFKVKVQKAFLSALYAGVSLMGFTLILGAFTPIITPMVKNMSQVmagvTGVnlntfdvG 89  Anaerostipes...
KRK50448          7 TIFQtfGASVVVPIIIFIIALLLRVKPKTAMMSAFYAGVGLTGFTWIITEFTPVVTKIVRQMVDN----TGIklpvvdiG 82  Lactobacillu...
Q1WU03            7 NFFTifGASIIVPIIIFIIALFLHVKFSKAIMSAFYAGVGLTGFNWVIAEFTPIVTKIVKQMVNN----TGIklpvvdiG 82  Lactobacillu...
WP_015509813     10 NIMDm-GASVMLPVVIFILSCVFRMKIGKALKTGLLVGIGFQGLGLVVGLLGTSLQPAIDYYQE-----MGSgyttmdvG 83  Enterococcus...
5ZOV_A           82 AVIDPYTSMQAtIQtmadnyawVGYAVILALFLNILLVVCRRitgIRT--IMLTGHIMFQQAGLVAVFymiigaSMWETV 159 Pasteurella ...
wugsc:KPN_03550  83 WPGSSPMTWASq-I--------ALVAIPVAIAVNIVMLVTRMtrvVNVd-IWNIWHMTFTGAMLHIAT------GSYWIG 146 Klebsiella p...
jgi:Sterm_3385   89 WPGTAPMTWASk-I--------AIVAIPVAILVNLIMLALKMtrvVNVd-IWNIWHMTFTGALVHIVT------GNYWLG 152 Sebaldella t...
WP_006565684     81 WPAASGIAFGSgTF--------VLASIVTFLIVNVICLAIKIthtLNVd-IFNYWHFILIGTVSYFVT------GNFILG 145 Anaerostipes
WP_009291131     83 WQAVASVAYSTd-I--------GMMFIGVGLIFQIVIFLVKItdiFQPsdLWNNYSIIVWGSLLYQIK------GNLVMS 147 Anaerostipes
WP_012862968     84 WQASAIVGYSTk-I--------GMIFVGLGLLFQAVLFLLKWtniFMPgdLWNNYSYMLWGSMLYFVT------GNLWLS 148 Sebaldella t...
WP_006568142     90 WQATSVVAFATs-A--------GMIYLGLGILLQTILFLVKWtniFQPsdLWNNYSYIVWGAMVIFKT------HNFILG 154 Anaerostipes...
KRK50448         83 WQAGSLAAFGSt-V--------GLSFFVFGLLAELILFALGVtkvFLPsnIWNNFGYMIWGTLAFYVT------HNYWLS 147 Lactobacillu...
Q1WU03           83 WQAGSLASFGSs-V--------GITFFVFGLIFELIIFALGItkvFMAsnLWNNFGFMIWGTLAYYVT------HNFWLS 147 Lactobacillu...
WP_015509813     84 WAAVGAASWSVp-F--------AAIAILMIVGLNVLFILLKWttvMNVd-IWNYIHFLIPGALAYALF------NSFWLG 147 Enterococcus...
5ZOV_A          160 IYTAVLMALYWGISSNIMYKPTQAVTG--GAGFS-IGHQQQIASW--IAVKLAPKLgdkndtvDKM-----------KLP 223 Pasteurella ...
wugsc:KPN_03550 147 ILGVVVHAAFVYKLGDWFAKDTRDFFG--LEGIA-IPHGSSAYLGp-VAVLVDTII-------DKIpglnrihfsadDIQ 215 Klebsiella p...
jgi:Sterm_3385  153 ILGVVVHAVFSYKFGDWFQYDTRDYFG--LEGIA-VPHGTSAYCAp-FAVIVDAIL-------DKIpginkididteKLE 221 Sebaldella t...
WP_006565684    146 IVVGTLFMMVNTILGERQEQVITDFAGeqMAGLTfSTQGFPLQLL--FARGVDWVI-------DKIpglnkisfnlgNLP 216 Anaerostipes
WP_009291131    148 FVLMLFVNLVVLLLAEIVQKRWSTYYH--YPGCA-MIAPHHMGDVp-LYLVLDFIL-------GKLgadki-nlrpdAIK 215 Anaerostipes
WP_012862968    149 LGCMLVMNLYTLLLAEVVQKRWSKYYG--YPNCT-ITAPHHIESVp-YAIAMDWVL-------NKLganki-kldpeNLK 216 Sebaldella t...
WP_006568142    155 IACMILLNLYSLLISELVAKRWSKYYN--YPNCT-IIAMHNVEPAi-FAILFDPIL-------NKLgfnkl-klnpkSIE 222 Anaerostipes...
KRK50448        148 LGLEFFMLLYSLVLAEIQADRWADYYG--IENTT-VDSLHNIEQVv-PAIILDPLW-------NLLgfnkv-kmtpkDFQ 215 Lactobacillu...
Q1WU03          148 LSLSFFMLLYTLVIAEIQADRWSEYFD--IKNAT-VASLHNIEQTi-PAILLDPLW-------NLLgfnkv-kltpkVFK 215 Lactobacillu...
WP_015509813    148 LTVTVGLSIVTLFVAQWFAPRWEAYYG--LEGTT-CTTFSFITFAypFGLLVNKLI-------DLIpglnkidisleKVE 217 Enterococcus...
5ZOV_A          224 KWLHIFHDSISATALVMTVFFGIIllsfgldnlqqmagK------THWFMYIFEMGLKFAVAIQIIVTGVRMFVAELSEA 297 Pasteurella ...
wugsc:KPN_03550 216 KRFGPFGEPVTVGFVMGLVIGALA--------------Gy-------dLKGILQLAVKTAAVMLLMPRVIKPIMDGLTPI 274 Klebsiella p...
jgi:Sterm_3385  222 KKLGAFGQPIIVGFILGLIVGILA--------------Gy-------gPKQVLQLSVSVSAVMYLMPKVIKPIMEGLLPI 280 Sebaldella t...
WP_006565684    217 SSISFFGEPMILGFLLGGIMSFLA--------------Gy-------kWDAALVVAVGLSAAMFLLPRMVSIMMEGLAPL 275 Anaerostipes
WP_009291131    216 KKIGFLGEPMYVGLIVGLILGIVG--------------NistlneMTSWGQVADVAVTCSAVMAIFPKIAGLFASGFTVI 281 Anaerostipes
WP_012862968    217 KRLGLLGEPMFLGLILGLFLGILG--------------NlkdlgqLASWGEIATVGISTAAVLAIFPKVAGIFASAFQIL 282 Sebaldella t...
WP_006568142    223 KKIGFLGEPMTLGFFLGMFIGILG--------------SinklgtIAGWGDILEAAIATSAVMAIFPKIASMFAQAFAPI 288 Anaerostipes...
KRK50448        216 KKLGVFGEPITMGIILGLIIGILG--------------NlsslgkISAWGQITKFAIQLAAVMAIFPLVTNVFAKAFIPI 281 Lactobacillu...
Q1WU03          216 DRLGVFGEPTSLGIILGIIIGILG--------------NlnnltdIDAWGEVLKFAIQLAAVMTIFPLITDVFAKAFIPL 281 Lactobacillu...
WP_015509813    218 SKIGFFGDPAVIGLLVGTFLGVLT--------------Rq-------eFTVAISMGVGVSAVLVLIPKMVSVMMEGLTAI 276 Enterococcus...
5ZOV_A          298 FKGISERVIPNSVL-------------AIDCAAIYAfSPNAMVFGFMWGAIGQFVAvglllgfsspiL---IIPG--FIP 359 Pasteurella ...
wugsc:KPN_03550 275 AKQARKRLQAK-FGgqe-------fliGLDPALLLG-HTSVVSASLIFIPLTILIA-----------V---VVPGnqVLP 331 Klebsiella p...
jgi:Sterm_3385  281 SEAAREKLSAK-FGgge-------fliGLDPALLLG-DANVISAGLLFIPLTVIIA-----------AigsITFGnrVLP 340 Sebaldella t...
WP_006565684    276 TDAARDFMNTR-FPgrk-------fniAMDYCMLLG-DRDVITMGIITVPIVLGLA-----------I---ILPGnrFLP 332 Anaerostipes
WP_009291131    282 TDYSRKTLKKSKYGkdre------fiiAVNDALGYG-EAATLTTGLLVIPVALLLA-----------F---ILPGnvVLP 340 Anaerostipes
WP_012862968    283 TEASRGTAKAGGKSrew--------ylAINDAAGYG-EPATLITGIMLIPIILAAS-----------F---LLPGnkTLP 339 Sebaldella t...
WP_006568142    289 TEAARKFMGKAGDrew---------yiAVNDAVGYG-EPATLTSGLLLIPIMIVVS-----------T---ILPGnqVLP 344 Anaerostipes...
KRK50448        282 ATEIDEQQKKRHGEnknsrydkkrwflAVDDGVGYG-ESATLISGIILIPIMVLIA-----------F---ILPGnkTLP 346 Lactobacillu...
Q1WU03          282 ADAIDSRQKEEMKEkthpk----rwflGIDDGVGYG-EPATIISGMILIPIMVLLA-----------F---VLPGnrTLP 342 Lactobacillu...
WP_015509813    277 GEAAKEFMKKH-IGegkk------lyiGMDIALGLG-DPTAITTTVILIPIAIFLA-----------F---IIPGmhYFP 334 Enterococcus...
5ZOV_A          360 MFFSNATIGVFANQFGGWKSVMKICFIMG----IIEVLGSAWVIHLlatqgttfnGWMGM-------AD 417 Pasteurella multocida
wugsc:KPN_03550 332 FGDLATIGFFVAMAVAVHQGNLFRTLISGviimGITLWIATQTIGLh--------TQLAAnag--alKA 390 Klebsiella pneumoniae s...
jgi:Sterm_3385  341 FGDLATIGFFIAMAVAIHHGNIFRTLISGsfimFITIWISNQTVELq--------TILAKnan--mlGG 399 Sebaldella termitidis A...
WP_006565684    333 FTDLTALPYWMIGVVIGTKRNSFRALIAAvltlCIGLWIATDLAPLi--------TQMAAgvgfkfeAG 393 Anaerostipes
WP_009291131    341 VMVLPSLPYMVEVPVSLSNGNIFKSWIAAcivfCAKLLMASSWAAVf--------TEIAVnagyevtAG 401 Anaerostipes
WP_012862968    340 MVDLIALPYMVELIICVGNGNIFKSVISGgiwyAIALYTCSAVAPIf--------TEVALstgvsipAG 400 Sebaldella termitidis
WP_006568142    345 VVDLLAIPYMVQGLVAVYKGNMSKILVAGtiwfSLGLLMCTYTAPLf--------TQVAIsagfaipAG 405 Anaerostipes caccae
KRK50448        347 VVDLIAIPYMIESIVAVTRGNILKVIATGivwfSLGLYAASWLSPVy--------TAAVAhygvaipTG 407 Lactobacillus reuteri D...
Q1WU03          343 VVDLIALPFMVESIVAITRGNILKIIANGiiwfSLGLYASSWLGSIy--------TEAVSnygatipTG 403 Lactobacillus salivariu...
WP_015509813    335 VGVLTVIVYMIPLLALASNGNLFRTLVTGffflVIVLIGTNTFAPEa--------TEMMNatg-vpvEG 394 Enterococcus casseliflavus
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