3AJE


Conserved Protein Domain Family
Sua5_C
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pfam03481: Sua5_C (This model is not part of the current CDD release)
Threonylcarbamoyl-AMP synthase, C-terminal domain
This domain can be found in the C terminus of threonylcarbamoyl-AMP synthases, including Sua5 from Saccharomyces cerevisiae and YwlC from Bacillus subtilis. Threonylcarbamoyl-AMP synthase is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. This domain adopts the Rossmann fold and may be involved in GTP and/or tRNA binding based on structural similarity with both GTP and tRNA binding proteins.
Links
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Statistics
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PSSM-Id: 515615
Aligned: 479 rows
Threshold Bit Score: 47.316
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3AJE_A        201 TIEELKKL-FGeI----VipefaqgKke--------aEIA----LAPGMKYKHYAPNTRLLLVEN---RNIFK----DVV 256 Sulfurisphaera...
WP_014558919  186 TSEEIE-----------T-------Evsl------kpINKkrkiSAPGMMKSHYSPAKPIYILNEtllR----------- 230 Ignavibacteriu...
WP_014855383  194 PIEEIEKIt--gV----L-------Kkrd-----kneTSP----ESPGQLPFHYSPEIPLYIIDKsimSNNN-------F 244 Melioribacter ...
WP_013906670  192 PMEALKEVlg-eI----K-------Ikr-------kpEKP----KAPGQLKSHYAPRTPLKIWQKnl------------- 235 Thermodesulfat...
WP_013455637  192 dVDQIESLi---Gkv-rI-------Lph-------ssSKP----DAPGMLKSHYAPSKNIIL-GNieeLI---------- 238 Marivirga trac...
WP_014796942  195 AIEELEKVvGKlivkehS-------Nsnp-----nqkKVA----SS-GMLLSHYAPKIKMRL-GNieeILNEY-----QS 251 Bernardetia li...
ACE06118      192 eiASIEKLvGTvil-hnN-------Ltas-----npiEKL----VTPGSLSYHYSPNKLLKL-GNmsdLL---------- 243
WP_015333227  191 aLEALEAVv--gRsf-rV-------Qsh-------saSNP----SAPGMLSSHYAPRKPTAL-LNdaaG----------- 237 Fibrella aestu...
jgi:Dfer_0231 224 diNEIESLi---Gpv-aL-------Mph-------stSDP----KAPGMLKSHYAPRKPLHL-YRrdaI----------- 269
Q2JMM9        208 PLEALEAHlGLp----iR-------LppeqapkdgttGPP----EAPGRLSSHYAPSKPLRL-LPtpfAQLQPgdwqQVQ 271 Synechococcus ...

3AJE_A        257 SLLSKKYKVALLIPKELSKEf------eGLQQIIL---------------------GSDENLYEVARNLFDSFRELDKLN 309 Sulfurisphaera...
WP_014558919  231 --KIDFNKAGLLSFTKKYDKff-----kKVITLSE-----------------------SMDLKECAVNLFSAIHLLEdsd 280 Ignavibacteriu...
WP_014855383  245 LNSLKNRKAGLLLFKESNPEiesilpsySKKILSE-----------------------TGNMAEAAANLFKFLHDFE--- 298 Melioribacter ...
WP_013906670  236 --eIKGKKIGFLAFSKAPEGky-----eAVRILTP-----------------------SGDLREAAANLFKYLHELD--- 282 Thermodesulfat...
WP_013455637  239 -EQNSNLKLGVLSFSKYYKDv------eTSLMLSK-----------------------SKDMHEAAKNLFSHLRKLD--- 285 Marivirga trac...
WP_014796942  252 NQELESNEIGILSF-------------------YEkynqvpv--------qnqfvlSKKQDYSEAAQNLFSYMRELDKLN 304 Bernardetia li...
ACE06118      244 -VTYGSQKVGILAF-------------------DQyyegvnk--------gqqillAPTGKVEEAAYNLFAALRELDQLD 295
WP_015333227  238 --YVASPTAGALVFNDYLPNip----teQQLRLSP-----------------------TGDLNEAAKNLFSYLRQLD--- 285 Fibrella aestu...
jgi:Dfer_0231 270 --TPGDAGTGYLLFDRYLDGvd----rrYQRLLSP-----------------------GHDLKEAAHNLFAYLRELD--- 317
Q2JMM9        272 HLTTGHSHLGILSF-------------------ATdpqallntlsrhwpgitfsleCLGSDPKAAARALFASLRRLDEGD 332 Synechococcus ...

3AJE_A        310 VD----LGIMIGFP--ERGIG-FAIMNRARKASG 336 Sulfurisphaera tokodaii str. 7
WP_014558919  281 ----veIIIAE--PvpETGIG-IAIMDRLKKAAy 307 Ignavibacterium album
WP_014855383  299 -KekvdLILTE--PvePSGLG-LAIMDRLKRAAe 328 Melioribacter roseus
WP_013906670  283 -QmgldLILVE--PvpEEGLG-LAIMDRLRKAea 312 Thermodesulfatator indicus
WP_013455637  286 -EsnvdLIITE--KvpSEGLG-KAINDRLQRAAv 315 Marivirga tractuosa
WP_014796942  305 IK----IILAELLP--EKELG-RAINDRLRRAAy 331 Bernardetia litoralis
ACE06118      296 ID----VILCSLVP--HQGLG-MAINDRLVRASa 322
WP_015333227  286 -AmpveRIYIQ--PvpDEGLG-RAINDRLRRAAA 315 Fibrella aestuarina
jgi:Dfer_0231 318 -GlpvsEIKAE--LvpASGLG-LAINDRLQRASv 347
Q2JMM9        333 AT----LLLAEPPP--ISTGLgYAMMDRLRRASs 360 Synechococcus sp. JA-2-3B'a(2-13)
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