5YHI


Conserved Protein Domain Family
MOSC

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pfam03473: MOSC 
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MOSC domain
The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes. These MOSC domains contain an absolutely conserved cysteine and occur either as stand-alone forms or fused to other domains such as NifS-like catalytic domain in Molybdenum cofactor sulfurase. The MOSC domain is predicted to be a sulfur-carrier domain that receives sulfur abstracted by the pyridoxal phosphate-dependent NifS-like enzymes, on its conserved cysteine, and delivers it for the formation of diverse sulfur-metal clusters.
Statistics
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PSSM-Id: 397510
Aligned: 331 rows
Threshold Bit Score: 38.7138
Threshold Setting Gi: 226521251
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5YHI_B        52 EKKVHGGPDRALCHYPREHYLYWAREF--PEQa-----------------------eLFVAPAFGENLSTdGL------- 99  Escherichia col...
EFX01259     231 DPWLTFTDCAPLLVTSEASGANMSARMsaGM--------------------------AVPMYKFRPNIVV-DGeaaw--- 280 Grosmannia clav...
XP_006961946 186 PDWLTFSDMAAYLVASEKSLSNVNARLssGP---------------------------VDIVRFRPNIVV-DGegege-f 236 Trichoderma ree...
XP_013941455 194 PDWLAFADMAAYLVVTEKSLRNVNARFsnTDN-------------------------AVDIVKFRPNVVV-DGevdf--- 244 Trichoderma atr...
XP_002478780 211 EEILTFADCASYMVVNEESVKDVASRp-gQG--------------------------KVEVTRFRPNIVI-GGaesa--w 260 Talaromyces sti...
CCT72482     281 PAIHGYTDQQPVNVNSLASVHAVSALLpkENQ-------------------------PLNALRFRANIWI-KGapaf--- 331 Fusarium fujiku...
Q2U121       287 PSVHGYTDQQPININSLSSVHAVSTLLpkENQ-------------------------PLNAFRFRANLWI-TGapaf--- 337 Aspergillus oryzae
EQB51721     287 PSVHGYTDQQPVNLNSLSSVHAVSALLppENQ-------------------------PLDALRFRANIWI-TGapaf--- 337 Colletotrichum ...
EMC93258     228 DFRVGFGDAFPVNLMGLASVKAIDDSLpsDTSak----------------------gQLDPTRFRANFYI-TGtapf--- 281 Baudoinia panam...
CBQ67766     260 KRGIEFQDEYPLLVASRESLESVRAQLsaALSsedgsdgrggraitgidahkwsdvsALSIARFRPNIVV-KGsaglqaf 338 Sporisorium rei...
5YHI_B       100 ---TESNVYM--------GDI------------------FRWGEali----------------------qvSQPRS-PCY 127 Escherichia col...
EFX01259     281 sedFWAELQI--------TSSdeaadgqgnhvdkardfrLLLTSncarctslnv--------dygtgapaaGELGE-VLK 343 Grosmannia clav...
XP_006961946 237 dedFWAELSI--------RSRp----------------aLAMTKmcnrctslnv--------dyetgrfgeGEKGM-VLK 283 Trichoderma ree...
XP_013941455 245 dedFWAELSI--------GGRp----------------vLALTKlcdrctslnv--------dydtgrfgeGEKGT-LLK 291 Trichoderma atr...
XP_002478780 261 eedFWSELTL--------ASAtde-------------vqLILTSncircrsldv--------dfetgdfhkADDGI-IYK 310 Talaromyces sti...
CCT72482     332 deeTWKRYRVvpkqqdaaSPS------------------LSVVCrtsrctlpnvnpltgkfdtdnphgdrtRGNAQ-PSS 392 Fusarium fujiku...
Q2U121       338 deeSWKRYRIlpkgpdagPRAdva-------------ptVSVVCrtsrctmpnvdpetgkpstdnpppekkRGKPQ-PSA 403 Aspergillus oryzae
EQB51721     338 aeeSWKRYRIlpkavsdeKRAeva-------------pkLSVVCrtsrctmpnvnletgtfeadipvagkkKGKPQ-PSA 403 Colletotrichum ...
EMC93258     282 tedTWKKITV--------GRRigrndkg----lfecdaeYHVACrtarcklp------------nvdqdtgvKDRNePYT 337 Baudoinia panam...
CBQ67766     339 sedSWERIWIlpdpsaqqSNAm-----------------LQLVArcqrcllt-----------avdpitaeKDPSV-PLK 389 Sporisorium rei...
5YHI_B       128 KLNYHFdiSDIAQLMQ-------NT-GKVGWLYSVIAPG-----------KVSADAPLE 167 Escherichia coli K-12
EFX01259     344 RLSK-D--RRVDTGIK-------YS-PVFGRYAFL---Dgsr------dvVVAVGDSVd 382 Grosmannia clavigera kw1407
XP_006961946 284 KLMS-D--RRVDKGSK-------WT-PVFGKYGFL--VDgld------glDVAVGDEVA 323 Trichoderma reesei QM6a
XP_013941455 292 KLMA-D--RRVDRGAK-------WE-PVFGKYAFL--VDgld------gaDVSVGDEVA 331 Trichoderma atroviride IMI 206040
XP_002478780 311 KLNK-D--RRVDQGAK-------YK-PVFGRYGFL---Redv------vaKVRVGDAVT 349 Talaromyces stipitatus ATCC 10500
CCT72482     393 TLVK-H--RTVEDGNP-------RAlGYLGMHCVPENAGlqqatdsveslYVQVGDEIE 441 Fusarium fujikuroi IMI 58289
Q2U121       404 TLVK-F--RRVEDGNK-------SAlGYIGMHCVPEDRAlrmaeeqekglYVAVGDEIE 452 Aspergillus oryzae
EQB51721     404 TLIE-H--RTVETGNP-------SAlGYIGMHCVPEDQDleeakeqraglYVEVGDEIE 452 Colletotrichum gloeosporioides Cg-14
EMC93258     338 TLSK-T--RKVDTGAY-------PH-PCLGMQTIPMFERg----------IIRVGDEVQ 375 Baudoinia panamericana UAMH 10762
CBQ67766     390 LLNRSR--MRVKKSAGvqgghgrAG-PCFGMYAIPLPLGaasge-kgaygRLETGDAVR 444 Sporisorium reilianum SRZ2
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