2O3G,2NQW,2P3H


Conserved Protein Domain Family
CorC_HlyC

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pfam03471: CorC_HlyC (This model is not part of the current CDD release)
Transporter associated domain
This small domain is found in a family of proteins with the pfam01595 domain and two CBS domains with this domain found at the C-terminus of the proteins, the domain is also found at the C terminus of some Na+/H+ antiporters. This domain is also found in CorC that is involved in Magnesium and cobalt efflux. The function of this domain is uncertain but might be involved in modulating transport of ion substrates.
Statistics
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PSSM-Id: 515606
Aligned: 104 rows
Threshold Bit Score: 44.45
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2O3G_A        14 NPDESLTVEGALEYVELAPQLNLPQQE-EDadFH-TVAGLIXEELQTIPDvGDF--A--DfhGWRFEVVEKEGQRIERVK 87  Neisseria menin...
EDM19247     331 IDEHEYVLSGRLEIEKVNETFGLDLPEsDE--YL-TVGGLILNQYQSFPKlHEV--IrvG--RYQFKIIKVTATKIELVR 403
Q73QX3       344 VDGTHILIPGAVPIIQLNSILNTDFHS--D--YNdTIGGLILETAEYLPKeGEl----iTigEVDFKVEKVETSKIISLI 415 Treponema denti...
O83072       371 VGTHEILCSGTVPLEYFNEVLGTRLQS-RV--YH-TVGGLLLERFGRLPTvGDE--LviE--GLRFKIRRVLDRYVVSAL 442 Treponema pallidum
Q9RZJ8       347 VSGGRVSVRGDVLLETLNSRLSLKLPT-DE--VD-TVSGLLWLELGRLPLvGDE--IviEptSLRLRVDAVERRAIRRAS 420 Deinococcus rad...
Q8ESI4       199 LAGNRYRIHANSPLYELEGILGITFPV-ED--YD-TLSDFLIDQLGYIPAnHEkpnLlyK--NIQFEITEISSQKIHSAI 272 Oceanobacillus ...
3_pfamImport   1 LAGHGYIVGGRAELDELSEHLGIEFPD-ED--FQ-TLNGFMLYELGRLPYeNEK--IdiTykGYNFETIGIKDKMIDKVR 74 
ABK77603     339 IDRDTIITSGDIEINRINEIFKADVPEgED--YA-SLSGLLHERLHDIPQeGDK--VevG--SLRIIVEEVKKNVPKKVR 411
Q5NH00       341 LEDNSYLIGGSATLREINRHIGIEFES-ED--AK-TLSGLIIEEIENLPSgPCC--IkyN--NILLEITNIRDNKIVSIK 412 Francisella tul...
Q6AM85       211 IGDGMLLAHARIDIEKIERHFGVTLPE-GL--HE-SLGGLLIHLLGRLGAvGDI--VesS--GLRFEITNATNRHILQVH 282 Desulfotalea ps...
2O3G_A        88 ITKLP 92  Neisseria meningitidis MC58
EDM19247     404 LKVMe 408
Q73QX3       416 ADVSK 420 Treponema denticola
O83072       443 VDTRA 447 Treponema pallidum
Q9RZJ8       421 FDLPE 425 Deinococcus radiodurans
Q8ESI4       273 ATIYE 277 Oceanobacillus iheyensis
3_pfamImport  75 ITKV- 78 
ABK77603     412 IERIR 416
Q5NH00       413 LTItt 417 Francisella tularensis subsp. tularensis
Q6AM85       283 ITDMR 287 Desulfotalea psychrophila
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