Conserved Protein Domain Family
DUF294

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pfam03445: DUF294 
Putative nucleotidyltransferase DUF294
This domain is found associated with pfam00571. This region is uncharacterized, however it seems to be similar to pfam01909, conserving the DXD motif. This strongly suggests that members of this family are also nucleotidyltransferases (Bateman A pers. obs.).
Statistics
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PSSM-Id: 397485
Aligned: 72 rows
Threshold Bit Score: 89.5788
Threshold Setting Gi: 500047489
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q0A741       289 AELPSVARQAREAN----REASRAVTQLSEFHLQLQRRCVEILLTELaseglgpPPRRYALLVMGSLARRESLLNPDQDN 364 Alkalilimnicola...
Q74E96       133 RAIHDELNVLEMERflaiSSVSALHANCTEYRDILADRALALAEDEMehdgrgrAPCPYALCSMGSDGREEQTLITDQDY 212 Geobacter sulfu...
Q9K6I7       316 EAIHDILSTLLRDG----VPTIHMLEMITKLYDRLVQHCLQLTIDSFekeglgtPPVPFTWYMMGSSGRGEQFMPTDQDH 391 Bacillus halodu...
Q5KZZ8        30 RELRRCLAP---------EQMKQLAGDVVCVHEAILRRAFFLAERETmkrsvgiRPPAWCWYVMGSIGRCEPTIWTDQDH 100 Geobacillus kau...
Q5WB02        16 KRLRKQVLNMSKPF----AYAKELQAYHEQKLYAAVSNAGEEIKKELg-----eFPAPFAFFVMGSAGRKEQIYDSDQDH 86  Bacillus clausi...
Q0A740        45 AAQQRLVAQLRARG----LPAGRIQRRLTTLNNTVIRRLARQAVAVAlrrgagpPPVRFCLLVMGSGARDEHFLGPDQDH 120 Alkalilimnicola...
Q0A6Y9       155 QAQSDLAGDLLADR----LDAPEIQALLSGINEDIYRQLTANAVEGLaldgwgrPPAAFAVMVMGSGGRRESFLGPDQDN 230 Alkalilimnicola...
WP_012646757  87 IRFTLLTKEYFTRR----SSVIAFHGLCATFHDLLFRKALVLAQTGAgtm--ypdDIPCCLLATGSAGRKEFMPGTDSRY 160 Geobacter daltonii
Q72EX4       364 TRVDALAFDLLCEG----AGPEALHTVTARLHDRLALRLIHMAEETLg-----pPPVPYAFMTFGPAAREEALLRPVQRT 434 Desulfovibrio v...
WP_011728207  19 AELPAAARELV--G----ARAATVAHAWSALLRAALRTAARVTG-----------PAPGTWYASGSVGRGEALPGSDLDT 81  Mycolicibacteri...
Q0A741       365 ALIIADnrpgetepsPLDDRERRWFDTFADRLNHRLDALGYDWCQGHIMARTPVWHRQLGQWRQWVMTATRHPN---GD 440 Alkalilimnicola ...
Q74E96       213 LIVYGD---------GGGEAADEWFREFSELIVERLAQIGFKKCTGDIMPSNPTWRGSLSQWRRKLLAIVRYEY---ED 279 Geobacter sulfur...
Q9K6I7       392 FLVYQDte------kEEGAKVADYFKRFTEALVETLEKAGYRRCPGDMMASSPNWCGSLSMWRDRLRRWGLRAT---ND 461 Bacillus halodurans
Q5KZZ8       101 GILFNCp-------eEEEAACYEFIRHMAAVGVDMLHEAGYPYCSGYVMATNKRWAQSVRGWEQQLSSYLDSGW---PN 169 Geobacillus kaus...
Q5WB02        87 GIVFKG----------EDDRHLPYFLTFGERIVTQLEAAGYERCVGGVMASCERWCGSAEKWSQQLQHWLTKDT---FE 152 Bacillus clausii...
Q0A740       121 GMVLADyp------dRDHDAVDAWFRCYSSHLVERLEAAGFPRDTGDVMCTNPLWRKTLGQWTQQITTWARRAD---TV 190 Alkalilimnicola ...
Q0A6Y9       231 GLIIADyp------dAEHTAVDAYFAEFAARLNRDLDQVGIPYCQGHVMARNPLWRKSHSQWLAQLDYWMRSRR---PQ 300 Alkalilimnicola ...
WP_012646757 161 FLVYPD----------SQVHHAGYFEEMRYRLIALLDQCGIFGAGHRPIDDGGLWKGSESEWRSWSSSQMQRI----GK 225 Geobacter daltonii
Q72EX4       435 GIVFMPppde--aspETGMRAARYCRSVATFVTDGLAALGFARDPQGRMA--PALTLPLHRWMALCANGEATNEaegEA 509 Desulfovibrio vu...
WP_011728207  82 LFVRDE------------GTPVDAALHHALEVHDLLSACGIPGDEKGVTAARARFNRSASQWEDGIARWAGDAAa--DR 146 Mycolicibacteriu...
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