3ABI,1E5Q,2AXQ,4INA,4XQE


Conserved Protein Domain Family
Sacchrp_dh_NADP

?
pfam03435: Sacchrp_dh_NADP 
Click on image for an interactive view with Cn3D
Saccharopine dehydrogenase NADP binding domain
This family contains the NADP binding domain of saccharopine dehydrogenase. In some organisms this enzyme is found as a bifunctional polypeptide with lysine ketoglutarate reductase. The saccharopine dehydrogenase can also function as a saccharopine reductase.
Statistics
?
PSSM-Id: 397480
Aligned: 81 rows
Threshold Bit Score: 57.9854
Threshold Setting Gi: 81836163
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3ABI_A         19 VLILGAGNIGRAIAWDLKDEFD-----VYIGDVNNENleKVKEFA-----TPLKVDASNFDK-LVEV-MKEFELVIGALP 86  Pyrococcus hor...
A0BRK4         35 IGVLGYGAIGKAFTELLLKQHPka--nIVILDKHDAFfpNEkrf----ktVIYKQTRDNLTQtLDIMgLKEGDTLVDLST 108 Paramecium tet...
A0DNM8         20 IGVLGYGAIGSAFIEVLLKNHPna--qIVALDKYNAFraNEnrf----ecIIEERTKENIGDtLSRMgLQSGDILVDLST 93  Paramecium tet...
WP_012507661    8 ILIIGFGSVSQCTVPVLFKHINvdytqVTIMDFEDIRekVSPWTAlgvtyINHQITPYNIAQtLSSY-VAEGDLIIDLAW 86  Pelodictyon ph...
Q8TQB2         16 ILVIGYGSVSQCTLPLLLDKLDvplenITLIDFEDKSkaLKKYTNqglrfVCEKINPKNLDQvLSQY-MEDEGLIIDLSW 94  Methanosarcina...
WP_012106592    7 VLIIGYGAVSKCTLPILLRHVNiplenITIVDFKDKSqdLKAYTTrglrfLKRKITPENLTSiLTET-LGEGGLLVDLAW 85  Methanoregula ...
ABU43831       34 ILQIGCGGVGSSMPPLYKKHLKfssgnVIIIDKDRIKidKLSEKYpsmkfINTEVTKSNYKNiIDQH-LKKGDVFVDLAW 112 Paramecium bur...
ABT16724       41 ILQIGCGGVGSSMPYLYERHFQykagnITVMDKDKARldKLKAKFpkinfVHQEFTKKNYKQiITQY-LGKGDIFADLAY 119 Acanthocystis ...
jgi:Sama_3337  14 ILIVGFGSIGQGLLPLILRHIDitpqkICIITADDRG--REEAGKlgirfIEMPLTRKNYQSeLTPL-VGKDDFLVNLSV 90  Shewanella ama...
Q5WTV7         16 FVILGFGCIGQALMPLIFDKFDikpsqVTIIAAEGTK--IDAAQQygvsfKLQQITPQNYLEvIGST-LEENDFLIDVSI 92  Legionella pne...
3ABI_A         87 GFLGFKSIKAAIKSKVDMVDVSF---------------------MPENPLELRDEAEk-----AQVTIV 129 Pyrococcus horikoshii
A0BRK4        109 NIGFAEIWALCASKGVRYLNTALevwddsedanscpqnaeeaykLTLGYIKDNAKKSpf--wqKGPTSL 175 Paramecium tetraurelia
A0DNM8         94 NIEFLSIWSLCAEKKIRYMNTALeqwedsedanscpknseeaykLTLGYIKDKAKQSkywnpkSGATSI 162 Paramecium tetraurelia
WP_012507661   87 NIDCCEILQWCHDHGVLYINTSVevwdpytgvetrppaertlywRHMNIRRMTSQWKd-----KGVTAV 150 Pelodictyon phaeoclathrat...
Q8TQB2         95 NIDANDILTWCHNHSVLYVNTSVevwdptedfltrsllekslylRQMKLRELSRDWK------DSPTAV 157 Methanosarcina acetivorans
WP_012106592   86 NIDAGEIVQWCHDHNVLYVNTSVeawdplgerytaspvekslyyRQMKLRELTREWA------DSTTCV 148 Methanoregula boonei
ABU43831      113 YMNTKDLLTYCHEKGIHFVNTAIeswygeedckaktkecetlyrHQHAVRELAKSWGn-----KGATAV 176 Paramecium bursaria Chlor...
ABT16724      120 YIGTNDCLELCHEKGIHFTNAAIeqwlgssdcnqntlecetlyrHQHYVREMAKKWGn-----KGATAV 183 Acanthocystis turfacea ch...
jgi:Sama_3337  91 DVSSIALVEFCQARGARYLDTCIepwaggytdpsksfaarsnyaLRERVLALKDKYR------GGPTAV 153 Shewanella amazonensis SB2B
Q5WTV7         93 GISSLALIILCNQKGALYINAATepwkeefvmekmalnrrtnysLREEVLRLKDKTQ--------KTAL 153 Legionella pneumophila st...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap