2M83,2EEF


Conserved Protein Domain Family
CBM_21

?
pfam03370: CBM_21 
Carbohydrate/starch-binding module (family 21)
This family consists of several eukaryotic proteins that are thought to be involved in the regulation of glycogen metabolism. For instance, the mouse PTG protein has been shown to interact with glycogen synthase, phosphorylase kinase, phosphorylase a: these three enzymes have key roles in the regulation of glycogen metabolism. PTG also binds the catalytic subunit of protein phosphatase 1 (PP1C) and localizes it to glycogen. Subsets of similar interactions have been observed with several other members of this family, such as the yeast PIG1, PIG2, GAC1 and GIP2 proteins. While the precise function of these proteins is not known, they may serve a scaffold function, bringing together the key enzymes in glycogen metabolism. This family is a carbohydrate binding domain.
Statistics
?
PSSM-Id: 397445
Aligned: 57 rows
Threshold Bit Score: 95.7643
Threshold Setting Gi: 156113273
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2M83_A        26 QLQVQKAMLESTEYv-----pGSTSMKGIIRVLNISFEKLVYVRMSLDDWQTHYDI-LAEYVPN---SCDG-Et----DQ 91 
KHC80881     318 NSRESIVWLPSAYVlk---tdGKTFLYGLVNVQNLAFEKKVFLKLTLNNWKTSVIF-GGQSVINyfkSIDNkI-----DQ 388 Candida albican...
XP_001523261 362 KLGQGNVWLSSAYLlkqhntvNNAFLCGFILVVNLAFEKRLSLKMTLDNWKSSCKL-TGEKIISfvkSSGNi------DE 434 Lodderomyces el...
Q6FUA9       174 YLNGSNIKLHNLQK-------KTNKLKGLIYVNNLNFEKFIEVKFSFNNWKDIHYA-TATYNKSitdHIDEfRftidvMT 245 [Candida] glabrata
P28006       237 YLNGQNVKLHSLTQlg----dDSSKITGLVYVKNLSFEKYLEIKFTFNSWRDIHYV-TANFNRTinsNVDEfKftidlNS 311 Saccharomyces c...
EDO14854     240 YLNNQNIRLHSLKQlp----nETDKIYGLIYVNNLNFEKFIEIKFSFNNWQDIHYV-TASFNKSinsNIDEfKfvidlNS 314 Vanderwaltozyma...
Q6CRG5       451 YLQGNNIKLHECNSlq----lSQGKLTGLIYVNNLSFEKFIEIKFSFNGWKDIHYV-TANFKRTitdTVDEfQflinlSS 525 Kluyveromyces l...
Q74ZC4       267 FLQGHNIRLNKVSLv------DMHTIKGSLYVTNLHFEKFIEVKFSFDEWKNIHYV-TAQYLKTvtsKVDEfQfiidlSS 339 Eremothecium go...
Q6BKD5       189 DKQDMPCYLQSIKLs-----pEKTALVGLIMVKNLAFEKRLSIKLTFNAWRSVLIInNISYSK----SFSSiNf----DQ 255 Debaryomyces ha...
EDK36309     158 CTDGTPIYLSTLSLs-----aDSTSLNGMLMAKNIAFEKAISIKLTFDGWQSKLIInNVSYVR----SFAAiNy----DQ 224 Meyerozyma guil...
2M83_A        92 FSFKIsLVPPYQKDGS----------KVEFCIRYETSVGTFWSNNNGTNYTLV 134
KHC80881     389 FKFKIsLDDLISSDGKn--------vQLQMCIKYQVNDTEYWDNNFGKNYQFQ 433 Candida albicans SC5314
XP_001523261 435 FKFLInLRDLMNMTGDedeekfsgtmKLQMCVMYEVNGAVYWANNLGRNYTFD 487 Lodderomyces elongisporus NRRL YB-4239
Q6FUA9       246 FKYILkSKGLIYCDSYsnedctycdlSMDLCCRYDVNNETYYDNNNYKNYHIS 298 [Candida] glabrata
P28006       312 LKYILlIKRIITMEKNtss----cplNIELCCRYDVNNETYYDNNNGKNYHLF 360 Saccharomyces cerevisiae S288C
EDO14854     315 LKYTLqFKGLIYNDFNsnspitncnlNVNLCCRYDVNNETYYDNNNYENYQIS 367 Vanderwaltozyma polyspora DSM 70294
Q6CRG5       526 FVYFLkVKNLILFNSLis------plTIQLCCRYDVNGETYYDNNNYENYQVS 572 Kluyveromyces lactis
Q74ZC4       340 YKYFMkVKNLLYCVPGaret--wcpvTMSLCCRYDVNGETYYDNNNYENYQFN 390 Eremothecium gossypii
Q6BKD5       256 FKFVIpLEHMPKQL------------DLQFVIKYEVGGNSFWDNNNLKNYHIS 296 Debaryomyces hansenii
EDK36309     225 FRFSIpLQNLASVV------------NVEFVIKYEVANQTFWDNNLQRNYKLK 265 Meyerozyma guilliermondii ATCC 6260
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap