1SGJ,1DXE,2VWS


Conserved Protein Domain Family
HpcH_HpaI

?
pfam03328: HpcH_HpaI 
Click on image for an interactive view with Cn3D
HpcH/HpaI aldolase/citrate lyase family
This family includes 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase and 4-hydroxy-2-oxovalerate aldolase.
Statistics
?
PSSM-Id: 397422
Aligned: 18 rows
Threshold Bit Score: 215.29
Threshold Setting Gi: 499193511
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1SGJ_A         9 RSVLFAPGNRADLIAKLPRSAPDAVVIDLEDAVpgtaeakaaarPVAHDAARDLIA-AAPh-lAVFVRVNALHSPYFEDd 86  Deinococcus rad...
Q99ZK8         6 RTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVslkek--dtsrALVHFALKTFDY-SSV---ETVVRVNGLDS-CGALd 78  Streptococcus p...
Q8RDW5         9 RTMMFLPGNNPSMITDAYIYGPDSVMIDLEDATsvnqk--daarFLVSEALKTIDY-KTT---ETVVRVNGLDTPFGADd 82  Fusobacterium n...
O82487        90 LYGLFLLSFSPTLAEIAAHAGYDYVVVDMEHGP-----------GGIPEALDCIRAlNAAg-tSAILRLPENSPTWAKK- 156 thale cress
1DXE_A        20 QIGCWSALSNPISTEVLGLAGFDWLVLDGEHAP-----------NDISTFIPQLMAlKGSa-sAPVVRVPTNEPVIIKR- 86  Escherichia coli
Q9RYM1        24 QIGLWLGLADPYCAEICAGAGFDWLLIDGEHAP-----------NDVRSTLAQLQAlAAYp-vAPVVRPPVGDTHLIKQ- 90  Deinococcus rad...
2VWS_B        19 QIGLWLSSTTAYMAEIAATSGYDWLLIDGEHAP-----------NTIQDLYHQLQAvAPYa-sQPVIRPVEGSKPLIKQ- 85  Escherichia col...
A6THU5        15 QIGLWLGLCSSYSAELLAGAGFDWLLIDGEHAP-----------NNVPTVLTQLQAiAPYp-sQPVVRPSWNDPVQIKQ- 81  Klebsiella pneu...
O05151        18 QIGFWLALGDAYSAEVCAGAGFDWLLIDGEHAP-----------QDLRSVLAQLQViGAYrdcHAAVRVPSADTTVIKQ- 85  Rhodococcus jos...
WP_010891051  18 QLGFWLALAHPDIAEICAGQGYDWLLIDGEHGP-----------QTLPGIVAQLRAvEATppcSAIVRVPGHDSVTIKQ- 85  Novosphingobium
1SGJ_A        87 l-sVLTPELSGVVVPKLEMGAEARQVAQMLQERS---------------------------LPLPILAGLETGAGVWNAR 138 Deinococcus rad...
Q99ZK8        79 ieaVVLAGVNVIRLPKTETAQDIIDVEAVIERVErens--------------------ievGRTRMMAAIESAEGVLNAR 138 Streptococcus p...
Q8RDW5        83 iraVVKAGVNVVRLPKTDTPNEIIAVDKLIPEVEkei---------------------greGETLLMAAIESATGIMNVK 141 Fusobacterium n...
O82487       157 ---ALDLGPQGIMFPMIESRKDATKAVSYCRFPPdgirgsahtvvrasnygidegylsnyaEEILIMCQVESGEGVKKAD 233 thale cress
1DXE_A        87 ---LLDIGFYNFLIPFVETKEEAELAVASTRYPPegirgvsvshran-mfgtvadyfaqsnKNITILVQIESQQGVDNVD 162 Escherichia coli
Q9RYM1        91 ---YLDLGVQTLLVPMVDTPEQARQLVQATRYPPqgirgvgsalarasrwnavpdyltranDEICLLVQVESRLGLENLD 167 Deinococcus rad...
2VWS_B        86 ---VLDIGAQTLLIPMVDTAEQARQVVSATRYPPygergvgasvaraarwgrienymaqvnDSLCLLVQVESKTALDNLD 162 Escherichia col...
A6THU5        82 ---LLDVGAQTLLVPMVQNAEEARLAVRATRYPPagirgvgsalarasrwnrvpdyihqanDAMCVLVQIETREALKNLP 158 Klebsiella pneu...
O05151        86 ---YLDLGAQSLLVPMVDTADEAAAVVRACRYPPggirgvggarasr--wgryprylheadEQVCVVVQAETALALSNLE 160 Rhodococcus jos...
WP_010891051  86 ---VLDLGAQTLMVPMVETAEQAKAIVTASRYPPagerglggarasr--wggypayvaeanAQVCIIAQIETATAVDNIE 160 Novosphingobium
1SGJ_A       139 EIM-EVPEVAWAYFGAEDYTTDLGGKRTPGGLEVL----YARSQVALAARLTGVAALDIVVTALNDPETFRADAEQGRAL 213 Deinococcus rad...
Q99ZK8       139 EIAkASKRLIGIALGAEDYVTNMKTRRYPDGQELF----FARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQL 214 Streptococcus p...
Q8RDW5       142 EIAlASKRLMGIALGAEDYVTNLKTSRSKHGWELY----YAREAIVLAARNAGIYCFDTVYSDVNNLDGFRQEVQFIKDL 217 Fusobacterium n...
O82487       234 EIA-AVDGVDCVQMGPLDLSASLGYLWDPGHKKVRemmkKAEKSVLTTDPAKGGAYLSGFAMPHDGAGEIRGRGYHMVAG 312 thale cress
1DXE_A       163 AIA-ATEGVDGIFVGPSDLAAALGHLGNASHPDVQkaiqHIFNRASAHGKPSGI-----LAPVEADARRYLEWGATFVAV 236 Escherichia coli
Q9RYM1       168 EIA-AVEGVDGVFIGPADLSASLGHLGHPGHPDVAqaieDALRRIVGAGKAAGI-----LSADERLARHYLALGATFVAV 241 Deinococcus rad...
2VWS_B       163 EIL-DVEGIDGVFIGPADLSASLGYPDNAGHPEVQriieTSIRRIRAAGKAAGF-----LAVAPDMAQQCLAWGANFVAV 236 Escherichia col...
A6THU5       159 QIL-DVDGVDGVFIGPADLSADMGHGGNPQHPEVQaaieDAIQQIRQAGKAPGI-----LMANEQLAKRYLELGALFVAV 232 Klebsiella pneu...
O05151       161 AIA-EVDGIDGVFIGTADLAASLGFPGNPAHPEVQdailDALQRVRAAGKAPGV-----LTPVEDLAQKYLAHGAVFVAV 234 Rhodococcus jos...
WP_010891051 161 AIA-AVDGIDALFLGPADLAATEGLLGASSFDALFkltgEALARIVATGKPAGI-----LSRDERLVQQFLDGGARFIAN 234 Novosphingobium
1SGJ_A       214 GYSGKLCIHP 223 Deinococcus radiodurans
Q99ZK8       215 GFDGKSVINP 224 Streptococcus pyogenes serotype M1
Q8RDW5       218 GFDGKSCIHP 227 Fusobacterium nucleatum subsp. nucleatum
O82487       313 AVDVGLFRNA 322 thale cress
1DXE_A       237 GSDLGVFRSA 246 Escherichia coli
Q9RYM1       242 GVDTTLLARA 251 Deinococcus radiodurans
2VWS_B       237 GVDTMLYSDA 246 Escherichia coli K-12
A6THU5       233 GVDTTLLArg 242 Klebsiella pneumoniae subsp. pneumoniae MGH 78578
O05151       235 GIDTHLLAKQ 244 Rhodococcus jostii RHA1
WP_010891051 235 GIDSFTFAkg 244 Novosphingobium
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap