5L37,4JW0,4N8F,2QW7


Conserved Protein Domain Family
EutN_CcmL

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pfam03319: EutN_CcmL 
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Ethanolamine utilisation protein EutN/carboxysome
The crystal structure of EutN contains a central five-stranded beta-barrel, with an alpha-helix at the open end of this barrel (Structure 2HD3). The structure also contains three additional beta-strands, which help the formation of a tight hexamer, with a hole in the center. this suggests that EutN forms a pore, with an opening of 26 Angstrom in diameter on one face and 14 Angstrom on the other face. EutN is involved in the cobalamin-dependent degradation of ethanolamine.
Statistics
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PSSM-Id: 397416
Aligned: 181 rows
Threshold Bit Score: 50.1595
Threshold Setting Gi: 328810491
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5L37_D                   1 MLRATVTGNVWSTRRIEGIPAGAFLEVEVE-------------------------------GTGSRMIAFDVLGSGVGEH 49  Mycol...
WP_012374120             1 MRLGIVIGRVTLTQKEPVYNGGRLLIVQPWtraefaaasadrsgdatpssrpigsnialplPKGSSVIVYDELGAGIGSI 80  Opitu...
jgi:Isop_1632            1 MRIGQVIGRVTLNRAVHGFVGARLPILEPLpfealan------------------paapraRRSEEVVAYDDLGAGTGLL 62  Isosp...
WP_015245306             1 MRIAEVIGRVTLSRSHPSLRGARFVLALPMpleal---------------------tedsdKRGEDVVVYDDLGAGPGSL 59  Singu...
PRJNA63271:OPIT5_04230   1 MRLAHVIGKVTLSVADPSLRGGRLVIAQPLnrekfatp----------------ghpmlplAKGNSTVVYEALGAAEGQI 64  Opitu...
WP_013630376             1 MRIGEIIGHVTLSTYHPKLRAGRWKLAVPMklsal---------------------qgdpaGRSEAIVIYDELGAGLGSL 59  Rubin...
jgi:Plim_1748            1 MRLAEVIGRVTLSKCDPTVLGGTWIVAVPLlaeglaavi-------------hrdttmtvrGREEAIIVYDELGASPGDI 67  Planc...
jgi:Psta_3287            1 MRIAKIVGTVTLSRCHDTFVGASLRLAVPMtlpel---------------------rgetqPAADEIVVWDDLGAGLGSM 59  Pirel...
PRJNA52553:THIAE_09940   1 MEIHQVTHQLILTSRLDDLGHLPVKVLKSV--------------------------------SGGTAAALDPIGCKVGEW 48  Thiom...
Q31HD4                   1 MQILQVKKQLVLTSRLKDLGHLPLKALSSE--------------------------------TGEIFVAMDPVGTKDGDW 48  Hydro...
5L37_D                  50 VLIAQGSVAsswfTg----TPPPIDALIIGSID 78  Mycolicibacterium smegmatis MC2 155
WP_012374120            81 IGFTEGAEAtmpfT-----GDAPVDAYCACIVD 108 Opitutus terrae
jgi:Isop_1632           63 VGFSEGREAanpfGe----NPIAVDAYVACLLD 91  Isosphaera pallida ATCC 43644
WP_015245306            60 IGLSEGREAanpfGk----VKIPVDAYCACLld 88  Singulisphaera acidiphila
PRJNA63271:OPIT5_04230  65 IGFTEGAEAsapfD-----KPTPVDAYAAAIID 92  Opitutaceae bacterium TAV5
WP_013630376            60 VAIAEGPEAtapfHp----EQKPIDGYNAAILD 88  Rubinisphaera brasiliensis
jgi:Plim_1748           68 IAISEGAEAsapfHp----DSKPLDAYnaclld 96  Planctopirus limnophila DSM 3776
jgi:Psta_3287           60 IAVSEGGEAaqpfRp----KDKPVDAYAAAIFD 88  Pirellula staleyi DSM 6068
PRJNA52553:THIAE_09940  49 VFTIANSAA----RtasgdDRYLTDLTISGIID 77  Thiomicrospira aerophila AL3
Q31HD4                  49 VFTIANSAA----RdaagdKRLLTDLTVGGIID 77  Hydrogenovibrio crunogenus XCL-2
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