4JMR


Conserved Protein Domain Family
Gag_spuma_N
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pfam03276: Gag_spuma_N (This model is not part of the current CDD release)
Spumavirus gag protein, N-terminal
This is the conserved N-terminal domain of the Gag polyprotein from Foamyviruses (FVs) or Spuma-retroviruses. Gag is the major structural protein required for genome packaging virion assembly, trafficking and egress. This region corresponds to the Env-binding domain containing the cytoplasmic targeting and retention sequence (CTRS).
Links
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Statistics
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PSSM-Id: 515485
Aligned: 8 rows
Threshold Bit Score: 238.835
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4JMR_A        32 LDVEALVVILRDRNIPRNPLHGEVIGLRLTEGWWGQIERFQMVRLILQNDDNEPLQRPRYEVIQRAVNPHTMFMISGPLA 111 Human foamy virus
YP_009508555   8 LDVQALTDLFNNLGINRDPRHREVIALRMTGGWWGPATRYNLVTILLQDDQGQPLQQPRWRAEGRAANPAVMFTLEAPWQ 87 
P27400         6 LNVQELLNLFQNLGIPRQPNHREVIGLRMLGGWWGPGTRYILVSIFLQDDSGQPLQQPRWRPEGRPVNPLVHNTIEAPWG 85  Simian foamy vi...
YP_009508560  10 IDIGHLTILLRENGLPTNPPHGTEYAVRMTEGWWGDYARFTVIRVAFQDNQGNPLPRPEWEYINRDVRPLNDSIIGCTFR 89 
YP_009508581  13 LNVVELTYLLRENGLPGNPRDGQTYAVAMTEGWWGDHSRYRVVRVVFQDTSGNPLPQPQWMDEDRHMNPLQDPVIGCTFN 92 
Q7SIS7         8 LDVQELLNLFQDNGVTRNPRHLETIGLRMLGGWWGEQERYQSARIILQDDDGEPLQVPRWEEVLRPVNPLAHFVISAPWD 87  Simian foamy vi...
Q87039        12 LDVEALVVILRDRNIGRNPLHGEIIGLRLTEGWWGQLERFQMVRLILQDEDNEPLQRPRHEIIPRAVNPHTMFVLSGPLA 91  Pan troglodytes...
YP_009508565   6 LDIARLTVLLQENSLSGNPPHLTHYVLRMTEGWWGPFPRYTRVRIILQDESGNPLSQPRWELVDRMFNPLRDPILETTLD 85 

4JMR_A       112 ELQLAFQDLDLPEGPLRFGPLANGHYVQGDPYSSSYRPVTMAETAQM--TRD-ELEDVLNTQSEI 173 Human foamy virus
YP_009508555  88 DLRMAFDNIDLADDTLRFGPLANGNYIPGDEYSLEFIPPAMQEIAQM--QRD-ELENVLDIVGQI 149
P27400        86 ELRQAFEDLDVAEGTLRFGPLANGNWIPGDEYSMEFQPPLAQEIAQM--QRD-ELEEILDITGQI 147 Simian foamy virus (TYPE 3 / S...
YP_009508560  90 QAQQAFNNIDLARTPSRYGPLSNGLFLITDPEWLTFNPLSAVEIADL--DDQ-EIRDFLAHATIV 151
YP_009508581  93 QALRAFDQIDLGEGPSRFGPLADGMFLISDNAWMDFVPLSAMEITDL--DNErALREHLTYCCTL 155
Q7SIS7        88 QLRRAFHDLDVGNGALRFGPLANGNYIPEDPYSTSYRPVNPQEMAQM--QRD-ELEEVLEVQGEI 149 Simian foamy virus Pongo pygma...
Q87039        92 ELQLAFQDLDLPEGPLRFGPLANGHYVEGDPYSRSYRPVTMAETAQM--TRD-ELEDTLNTQSEI 153 Pan troglodytes foamy virus
YP_009508565  86 EMDRVFDGINLSPGTERYGPLCDGNFLYTDDAWNDFNPMSALEVADVelTPA-LYREHLNFLSRV 149
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