6EHR,3T1R


Conserved Protein Domain Family
Robl_LC7

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pfam03259: Robl_LC7 
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Roadblock/LC7 domain
This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.
Statistics
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PSSM-Id: 397386
Aligned: 37 rows
Threshold Bit Score: 51.8596
Threshold Setting Gi: 2495837
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6EHR_B              6 KALTQVLSQANTGGVQSTLLLNNEGSLLAYsg----yGDTDARVTAAIASNIWAAYDRNGNQAFnEDNLKFILMDCMEGR 81  human
Q9RW15             15 RVDQHLEELLGATGVRYCLLVDRKGFVLSHkealwapRPPALDSVATLVASNAAATTALANMLG-EPTFAEQTHQGENGT 93  Deinococcu...
MPITM:COCOR_01950  14 kINAVCDRLTKDANAKVVFLVDKNGQLISSag---qtQNIDTTSLASLTAGNVAAMGGLAKLIG-ENEFPNQFHEGAKDS 89  Corallococ...
3T1R_A             17 raVEVLEETLRETGARYALLIDRKGFVLAHkealwapKPPPLDTLATLVASNAAATQALAKLLG-EARFQEEVHQGERMG 95  Thermus th...
Q9DAJ5              3 EVEETLKRIQSHKGVIGTMVVNAEGIPIRTt-----lDNSTTVQYAGLLHQLTMKAKSTVRDIDpQNDLTFLRIRSKKHE 77  house mouse
Q22752              3 DFEETIRRLQSEKGVVGIIVVDSAGRVIHSt-----iDSDATQSHTAFLQQLCEKTKTSIRELDsSNDLTFLRLRTKKNE 77  Caenorhabd...
Q9V9P1              4 EIEDLLKRYQNYPNVSGIIILDPFAIPIKTt-----mEYTLTVHYAALISTLTYKAAKMITNLDaSNELVTIRLRTKVHE 78  fruit fly
Q9VQA6              4 EVEELLKRFQSMKNVTGIVVVDNDGIPIKTt-----lDYTLTLHYAALMQTVREKARQVVLDLDaTNEFTFLRLRTEQNE 78  fruit fly
Q9VJ18              5 TVQMTFDRLVQLPGVTGAILIDGNGVPVRTn-----lPANVARIYADRMRPLVILARSMVQDLEnGDELSYVRLRTRRQE 79  fruit fly
Q9W168             30 YDGDAFVNLFAHRGARDIMILDSHGVPLRSt-----cSQRRTFVFVSNLKPLLFMARNVVRDLDpSNDITFMRIRSNMGE 104 fruit fly
6EHR_B             82 VAITRVAN-LLLCMYA 96  human
Q9RW15             94 LYVESVGSdALLTLIF 109 Deinococcus radiodurans
MPITM:COCOR_01950  90 LYMTIVGSrVVLVVIF 105 Corallococcus coralloides DSM 2259
3T1R_A             96 LYVDEAGEhALLVLVF 111 Thermus thermophilus HB8
Q9DAJ5             78 IMVAPDKEyLLIVIQN 93  house mouse
Q22752             78 IMIAPDKDhVIMVIKD 93  Caenorhabditis elegans
Q9V9P1             79 VIVLPSENyIIIVVQN 94  fruit fly
Q9VQA6             79 VMLCPQEDyFIMVIQS 94  fruit fly
Q9VJ18             80 TMVATENEhTIILIQD 95  fruit fly
Q9W168            105 IHMTLGTDfILIVVQK 120 fruit fly
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