2YYG,1U8V,6VJR,6B1B


Conserved Protein Domain Family
HpaB
?
pfam03241: HpaB (This model is not part of the current CDD release)
4-hydroxyphenylacetate 3-hydroxylase C terminal
HpaB encodes part of the 4-hydroxyphenylacetate 3-hydroxylase from Escherichia coli. HpaB is part of a heterodimeric enzyme that also requires HpaC. The enzyme is NADH-dependent and uses FAD as the redox chromophore. This family also includes PvcC may play a role in one of the proposed hydroxylation steps of pyoverdine chromophore biosynthesis.
Links
?
Statistics
?
PSSM-Id: 515467
Aligned: 119 rows
Threshold Bit Score: 170.393
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
2YYG_A       278 TGALNHMAHQVvaLKTAKTEAFLGVAALMAEGIGAD-VYGHVQEKIAEIIVYLEAMRAFWTRAEEEAKEN---------- 346 Thermus thermop...
WP_012609721 284 FGTIQRQSKCS--CLAGHSDLVAGIAALVADVNGVL-NKSHIQDKLTHCMQMAEIAQGCAFGAAAAGKMH---------- 350 Desulfatibacill...
WP_015947302 283 FASLHRQSKCA--CSAGHCDMFAGAAALAADVNGVSgRASHIQEKITSMIMDGEAGYGCALGAAVNARRH---------- 350 Desulfatibacill...
Q970D3       288 FSAYHRQGYGG--CKAGLGDVIIGASMNLAKQLGVE-KASHVQEKLTEMIFLTETMYSAGIAASLNAVKV---------- 354 Sulfurisphaera ...
Q97V96       286 FSSYHRQGYGG--CKSGLGDVIIGAAYNLAKQIGVE-KAPHIQNKLNEMVLLNENMYGSGIAASLDAVKL---------- 352 Saccharolobus s...
WP_011700717 286 FTANYRACIGA--CVAGQGDVMIGAGALMARTNGLA-AAT-FSAKMVEMAVNNETTYCMGIGAMALGKKG---------- 351 Syntrophobacter...
Q24N71       300 FAHFHRHSYTG--CKTAVSEVIGAQAALVADVNDIA-KEHHVREKVCEIISTAELVFAAGQASALRAVKF---------- 366 Desulfitobacter...
Q3ABD4       280 FATYHRHSYTG--CKPAVTDIIMGTAALVAEYNGVE-KASHVRDALAELIAVAELVYGAGIAAGVKAKRA---------- 346 Carboxydothermu...
WP_014810811 281 FALFHRHSYSG--CKPAVGDILLGLASLVSEVNGIE-KADHVREHLAELITIAELGYAAGYTASSLGKPElfipgvgvrr 357 Desulfomonile t...
O29235       280 FALFHRHSYTG--CKPATTDMIMGFGALIAEYNGVY-EKHNIREKLVELAATAELVFAAGVAAAHYGQKS---------- 346 Archaeoglobus f...

2YYG_A       347 -A-YGLLVPDRGALDGARNLYPRLYPRIREILEQIGASGLIT--LPSEKDFKGP-LGPFLEKFLQGAA-LEAKERVALFR 420 Thermus thermop...
WP_012609721 351 -P-SGVFMPDSLKANAGLNYIKELTGEHIQMLHDIGGGIIVT--MPTARDYQNPkLKKLLDVTLAGNQkYTTEERMRALY 426 Desulfatibacill...
WP_015947302 351 -P-SGVWMPDPLIANSGLGAIRSKVGRHMEHLHDIAGGLIAT--MPTEADWNNPeLRKYMDKALRGNPkYTTEERLRAMH 426 Desulfatibacill...
Q970D3       355 -C-DNCWWVNPMHANVTKHLVARFPAQISQLSIDIAGGIIGT--APSEWDLKNPkLREYIAKYLQGVEgYTAEDRLRMVR 430 Sulfurisphaera ...
Q97V96       353 -CeDGCWWVNPMFANVTKQLVTRFPYEITKFSTDIAGGIIGT--APSEWDLKNPkLKPYIEKYLQGMMdYSTEDRLRMVR 429 Saccharolobus s...
WP_011700717 352 -P-GGMWVADSLTAHTNKVHVATLPYETKRLCQDIGGGVVETgcFPSSKDFNDPkYGHLVRKALQASAkFSAETRARAAR 429 Syntrophobacter...
Q24N71       367 -P-NGSWVPDEILTNAGRKLAGQKIYHEYETLADLTGGICAS--LPTEESFFAPeTAELCNKYIMRNPdYTAEETHRVMR 442 Desulfitobacter...
Q3ABD4       347 -A-SGTYIPEVVYANVARYHAGVNVYREFELLAELAGGLPAT--LPPEGDFYNEeTKGYLEKYLMRKAgISAENQHRCFR 422 Carboxydothermu...
WP_014810811 358 yG-PGSYIPNSIYANVGRCLTGDSVYHEQEILCKLAGGMPAT--FPFEQDLFNEdLKPLLDKYIRRNPnIPVEEQIKFWL 434 Desulfomonile t...
O29235       347 -P-AGTFIPNEVYANVGRRHAGLNYYKELEILAELSGGLPAA--LPFAEDFLSEeVGPYIRKYIKRRAdVPAEHVYRCLF 422 Archaeoglobus f...

2YYG_A       421 LAWDMTLSGFGARQELYERFFFGDPVRMYQTLYNVYNKEPYKERIRAFLK 470 Thermus thermophilus HB8
WP_012609721 427 LCRELSSTEFTGYYMGWGVNASGSPHTGHILVRSHYDLEYRIGIAKEWAG 476 Desulfatibacillum aliphaticivorans
WP_015947302 427 LIQDLAASRAAGTIMAFTINAAGSPATNQVVVRRAYDLDKQIRYAKELAS 476 Desulfatibacillum aliphaticivorans
Q970D3       431 LLENVSLG---VAFQIESVHGAGSPAAQRIMFSRLYDLNYAEEVAKRLAG 477 Sulfurisphaera tokodaii
Q97V96       430 LLENVGFS---VAFLIESVHGAGSPEAQRIAINRVYDYEYAEKIAKYLSQ 476 Saccharolobus solfataricus
WP_011700717 430 LSEWLTLGAGVPG----CMHGGGSPDGAKLVVRAFTPVNEFADYARKIAG 475 Syntrophobacter fumaroxidans
Q24N71       443 MMEDKLCDAFESAQAVAGVHGGGSPLMETITMMSRYDLEPLKDIAKYLAG 492 Desulfitobacterium hafniense Y51
Q3ABD4       423 FISDLLVSAQAGVKQVAGVHGGGSPIMEKITIYGQYNIEEKKKLAKYLAG 472 Carboxydothermus hydrogenoformans Z-2901
WP_014810811 435 FFTDFACSAAGAVFNYAGVHGGGSPIMEQIAITSQFDITSRKNIVKRLAG 484 Desulfomonile tiedjei
O29235       423 GISNILCSSLGGVQAVAGVHGGGSPVMEEIAIWRSYDFEKKKDIAKYLSG 472 Archaeoglobus fulgidus
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap