5ZWN


Conserved Protein Domain Family
LUC7

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pfam03194: LUC7 
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LUC7 N_terminus
This family contains the N terminal region of several LUC7 protein homologs and only contains eukaryotic proteins. LUC7 has been shown to be a U1 snRNA associated protein with a role in splice site recognition. The family also contains human and mouse LUC7 like (LUC7L) proteins and human cisplatin resistance-associated overexpressed protein (CROP).
Statistics
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PSSM-Id: 397349
Aligned: 61 rows
Threshold Bit Score: 205.528
Threshold Setting Gi: 470251816
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5ZWN_Y         9 AEQRKLVEQLMGRDFSFRHNRYSHQkrdlGLHDPKICKSYLVGECPYDLFQGtkq------------slGKCPQMHLTKH 76  Saccharomyces c...
Q4UEL9         2 DQIRATLAELMGKYEQKEDLDSTK-----PFTDPDVCRQYLTGICPHDLFENtkf------------ymGECSRIHSEKL 64  Theileria annulata
EDO06516       2 DEMRAQWEALMSNLENPADPYADK-----SFTDSDVCKMYLVGVCPYDLFENtvgrfgfkvndvqkhylGPCSKIHSDEL 76  Babesia bovis
EKC30213       5 EQMRAMLDELMGTSRDGENSKYKV-----KFDDPRVCKSFLLGCCPHDILSStrm------------dlGECPKIHDLAL 67  Pacific oyster
ELW68829       5 AQMRAMLDQLMGTSRDGDTTRQRI-----KFSDDRVCKSHLLNCCPHDVLSGtrm------------dlGECLKVHDLAL 67  Chinese tree shrew
EFX86367       5 DQMRAMLDQLMGTTRDGESSRYNV-----KFSDPKVCKSFLLGCCPHEILAStrm------------diGECVNIHDLAL 67  common water flea
BAH70989       5 DQMRAMLDQLMGTGRNGETSRYQV-----QFNDPKVCKSFLLYCCPHDILAStrm------------diGECPKIHDNAL 67  pea aphid
EFN73235       5 DQMRAMLDQLMGTGRNGENNKFQV-----KYSDSKVCKSFLLACCPHEILSStrm------------dlGECPQIHDLAL 67  Florida carpent...
EDW41893       5 DQMRAMLDQLMGTTRNGDER--QL-----KFSDPRVCKSFLLDCCPHDILAStrm------------dlGECPKVHDLAF 65  Drosophila sech...
3_pfamImport   1 DAQRALLDSLMGFNRDGDRPDEEAL----DFRHPRVCKSYLCGLCPRELFQHtrl------------daGACDLLHVPAL 64 
5ZWN_Y        77 KIQYEREvKQGK-------Tf--PEFEREYLAILSRFVNECNGQISVALQNLK-HTAEERmkiQQV-TEELDVLDVRIGL 145 Saccharomyces c...
Q4UEL9        65 RERYQNErKNHF-----------YGYELETLKIIQPMIDDCDKKIARGKARVE-EDLVRRktlDPMiIEEAKKIDSQIQS 132 Theileria annulata
EDO06516      77 KSKYLEErKSRY-----------YGYEEDTMRVIMPLIEDCDRRVQRGRMRAEdDGACKQttlDEAtVREAKRIDEEIEK 145 Babesia bovis
EKC30213      68 RADYEQAsKRKD-----------YYYDIDAMEHLSSFIADCDRKTELAKRRLK-ETQEELseeANGkAEMIHKLGEEMGT 135 Pacific oyster
ELW68829      68 RADYEIAsKEQD-----------FFFELDAMDHLQSFIADCDRRTEVAKKRLA-ETQEEIsaeVAAkAERVHELNEEIGK 135 Chinese tree shrew
EFX86367      68 RADYEKAsETKD-----------YGYQVDAMDHLTTFVGECDRKTEAAKKRLA-ETQEELsaeVAAkAQKVHLLAEQIGQ 135 common water flea
BAH70989      68 RADFEKAqQKFD-----------HYYDVDATEHLQAFISDCDRRTEAARKRLL-ETQEELtaeVAEkANAVHELAEKIGQ 135 pea aphid
EFN73235      68 RADYEAAqKKRD-----------HFYDIDAMEHLQNFIADCDRRTEQAKQRLA-ETQEELsaeVAAkANSVHVLAEEIGK 135 Florida carpent...
EDW41893      66 RADYESAaKTRD-----------YYYDIEAMEHLQAFIADCDRRTDSAKQRLK-ETQEELtaeVAEkANAVHGLAEEIGK 133 Drosophila sech...
3_pfamImport  65 RSAFLLHqKQEKdenrngyTyesFGYKRELANELSKLLVDVEKKIARAQKRLD-EDGDESq-----dKAQILQLTQEMQD 138
5ZWN_Y       146 MGQEIDSLIRADEVSMGMLQSVKLQELISKRKEVAkrv---rniTENVGQSAQQKLQVCEVCGAYLSRLDTDRRLADHFL 222 Saccharomyces c...
Q4UEL9       133 RMARADELGRNGEVEESFKIVEEVELLKRTKLEML---------EKGGDASYQSRLKPCDVCGALLSATDSDRRLTEHYS 203 Theileria annulata
EDO06516     146 KMKIADQLGMKGEVEESFKVLEEAELLKKNKLEML---------EKAGESSYQSRIKPCDICGALLSASDTDRRLTEHYS 216 Babesia bovis
EKC30213     136 KLAKAEDLGAEGLVVESLQLMEEVENLKKQKAAAEqey----rnSMPASSYQQQKLRVCEVCSAYLGIHDNDRRLADHFG 211 Pacific oyster
ELW68829     136 LLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEevy----rnSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFG 211 Chinese tree shrew
EFX86367     136 KLAKAEQLGAEGFVDESMKMMEEVEEFRKKKATAEqey----rnAMPASSYQQQKLRVCEVCSAYLGIHDNDRRLADHFG 211 common water flea
BAH70989     136 TLAKAEELGAQGLVDDSLKLMGEIEDLRKKKSEAEdty----rnSMPVSSYQQQKLRVCDVCSAYLGIHDNDRRLADHFG 211 pea aphid
EFN73235     136 KLAKAEQLGEEGFVEESMKLMGEIDELRKKKNEAEqey----rnSMPASSYQQQKLRVCEVCSAYLGIHDNDRRLADHFG 211 Florida carpent...
EDW41893     134 KLAKAEALGEAGEVEDSMELMKEIEELRAKKIKAEhey----rtSMPASTYQQQKLRVCEVCSAYLGIHDNDIRLADHFG 209 Drosophila sech...
3_pfamImport 139 VAVQAEQATRDGLVDKSLQLMEQVELLKKKRRELLrqstsaacgIAMSVDNVNQKLRVCDVCGAFLSIFDSERRLADHFG 218
5ZWN_Y       223 GKIHLGYVKMREDYDRLM------KNNRTTNASKT 251 Saccharomyces cerevisiae S288C
Q4UEL9       204 GKIHVGFQKLRDMSKTLSayiqenRHRLNGRgrng 238 Theileria annulata
EDO06516     217 GKIHVSYQKLRDMSKILKdyinehKPQSRSNNRry 251 Babesia bovis
EKC30213     212 GKLHLGFITIREKLEELKksiadrRMQREKEREEQ 246 Pacific oyster
ELW68829     212 GKLHLGFIEIREKLEELKrvvaekQEKRNQERLKR 246 Chinese tree shrew
EFX86367     212 GKLHLGFIKIREKLAELQvkveerRRQRHTQPVAD 246 common water flea
BAH70989     212 GKLHLGFIKIREKLSELEknyeerHEARRKFDeqe 246 pea aphid
EFN73235     212 GKLHLGFIKIREKLAELQktveerRKEKRESMLDR 246 Florida carpenter ant
EDW41893     210 GKLHLGFLTIREKLIELEktaaprKAELKRTgkmt 244 Drosophila sechellia
3_pfamImport 219 GKVHVGYVQIRNKLKEVMetmraeRKHEVGKRRMS 253
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