1XK8,1NZA,2ZOM,3OPK,1P1L,3GSD,3AHP,4E98,4IYQ,1KR4,6GDU,6T76


Conserved Protein Domain Family
CutA1

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pfam03091: CutA1 (This model is not part of the current CDD release)
CutA1 divalent ion tolerance protein
Several gene loci with a possible involvement in cellular tolerance to copper have been identified. One such locus in eubacteria and archaebacteria, cutA, is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The cutA locus consists of two operons, of one and two genes. The CutA1 protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. It has no recognised structural motifs. This family also contains putative proteins from eukaryotes (human and Drosophila).
Statistics
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PSSM-Id: 515379
Aligned: 371 rows
Threshold Bit Score: 87.1354
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XK8_A        40 FVTCPnEKVAKEIARAVVEKRLAACVNLIPqITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTDFVRSVHPYEVAEVIAL 119 human
WP_015018936   9 LSTFPsEKSVVDVADKVVRDRLCACVNFTQ-IRSIYSWRGKIEDQKEFVALFKTTATSAKRLKAEIARLHPYEVPEIVEL 87  Candidatus Nitr...
ABK77647      13 ISTYPdKKSASKAARGAVKSGLAACVNISR-ISSVYSWKGKIEEGSEYLAIFKTTQGRKARLKQEIGSSHPYDLPEIAEI 91 
WP_012214495   7 ISTYPdKKSITKIAKIFVKNKTVACVNISK-IDSIYSWNKKIENTSEYIAIFKTTSKNTKLLKEKIKETHPYNVPEIAEI 85  Nitrosopumilus ...
Q9X0E6         5 YSTFPnEEKALEIGRKLLEKRLIACFNAFE-IRSGYWWKGEIVQDKEWAAIFKTTEEKEKELYEELRKLHPYETPAIFTL 83  Thermotoga mari...
WP_013932548   5 YSTFPsEEKALEVCKKLLEEKLIACYNAFP-IKSGYWWNGEITYDAETAVILKTSKVKKELVFKRLKELHPYTTPAIFSI 83  Pseudothermotog...
WP_012003123   5 YTTFPdREKALEICKNLLLEKLIACFNVFQ-IDSGYWLDGKVSQDKEFAAILKTSNFKEQEVFKKLKELHPYSVPAIFSV 83  Pseudothermotoga
Q8U220         5 YTTFPtWESAEKVTKALLEERLVACANLRE-HKAFYWWQGKIEEDNEIGVILKTREDLWEEVKKRIKELHPYTVPAIIKI 83  Pyrococcus furi...
Q5JDG6         7 YTTFPdWESARKVTRELLERKLIVCANLRE-HEAMYWWEGKIEEGKEVGAIYKTEVSKWKELRETIKELHPYDVPMIARI 85  Thermococcus ko...
1KR4_A        27 YSTFPnEEKALEIGRKLLEKRLIACFNAFe-IRSGYWWKGEIVQDKEWAAIFKTTEEKEKELYEELRKLHPYETPAIFTL 105 Thermotoga mari...
1XK8_A       120 PVEqGNFPYLQWVRQ 134 human
WP_015018936  88 KMQdVSRPYLSWLAE 102 Candidatus Nitrososphaera gargensis
ABK77647      92 GMGeVDRQYMRWIEE 106
WP_012214495  86 DVTsINKSYLDWLID 100 Nitrosopumilus maritimus
Q9X0E6        84 KVEnVLTEYMNWLRE 98  Thermotoga maritima MSB8
WP_013932548  84 EVEeVDQKYLSWLVQ 98  Pseudothermotoga thermarum
WP_012003123  84 EIKtVDANYKQWLEE 98  Pseudothermotoga
Q8U220        84 NVEdVNEEYLKWLLE 98  Pyrococcus furiosus
Q5JDG6        86 DLDkLNREYSEWMAR 100 Thermococcus kodakarensis KOD1
1KR4_A       106 KVEnILTEYXNWLRE 120 Thermotoga maritima
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