5WU7


Conserved Protein Domain Family
Glyco_hydro_57

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pfam03065: Glyco_hydro_57 
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Glycosyl hydrolase family 57
This family includes alpha-amylase (EC:3.2.1.1), 4--glucanotransferase (EC:2.4.1.-) and amylopullulanase enzymes.
Statistics
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PSSM-Id: 397267
Aligned: 22 rows
Threshold Bit Score: 180.638
Threshold Setting Gi: 74570633
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5WU7_A    6 TFVLHTHIPYVRKHGk-----wPFGEEWLFEAMAESYIPLLMELEKlKERGvrfelvisftpvlmeqladeyiKREFE-- 78   Pyrococcus horikosh...
Q8ZT36   22 IFIFHNHQPWYLDFSk-----nELALPWVRMHAVGNYLKVPLLINQ-SGVSvaftlsgslieqlnwysngtytDARFRis 95   Pyrobaculum aerophilum
Q9HLU6  262 AIIYNDHQPLYKIVGs-----nNYVLPWTEVHATSEYIEQALIAHMfPQINvtyelsgsllyqlvnistdpyyNNTFIqy 336  Thermoplasma acidop...
O83182   12 AFAAKLTEACV--------------------------------------------------------------QSLHA-- 27   Treponema pallidum
P09961    8 SLGIHNHQPVGN-------------FDFVIERAY---------------------------------------EMSYK-- 33   Dictyoglomus thermo...
O32450    7 IFGIHNHQPLGN-------------FGWVMESAY---------------------------------------ERSYR-- 32   Thermococcus kodaka...
Q9KD04    7 SLVLHAHLPYVRHQEe-----dRLEERWLFEAMSETYIPLLWALEKlPVKHavtisftppv---memlsdplvQTRYL-- 76   Bacillus halodurans
Q8TZQ1   35 IIVWHQHQPYYYDPVq-----gIYTRPWVRLHAANNYWKMAHYLTEfPDIHvtidlsgsli--aqladymngaKDIYQii 107  Pyrococcus furiosus
O66934    7 VFWWHMHQPLYREPYt-----gEYLLPWTFFHAVKDYYDMPAYLKDfE-IKlnfnltpvlid-qiqeyaqgkaKDVFLea 79   Aquifex aeolicus
Q55545    8 AFVWHQHQPCYQSYGmvgnghgYYQLPWVRLHGTRDYGGLIKLWARyPSLHqtvsftpclla-qledyaqglaIDRHLal 86   Synechocystis sp. P...
5WU7_A   79 ------------------------------------KYMERKLKSMEEDLERFKDEKlre-------------------- 102  Pyrococcus horikosh...
Q8ZT36   96 ekiargepltieekyamlavpggffdinwqnilnkhPRYAVLLGVRNDAFNKCPPGNmtcvvsrfsd------------- 162  Pyrobaculum aerophilum
Q9HLU6  337 afipyselnttqnqsllanitadyfsipsyvykldePASNEYLELH-NIWASGGKLSkaqfed----------------- 398  Thermoplasma acidop...
O83182   28 ------------------------------------EHDPSQYQAFFSGLCRHEQLP----------------------- 48   Treponema pallidum
P09961   34 ------------------------------------PLINFFFKHP--------DFP----------------------- 46   Dictyoglomus thermo...
O32450   33 ------------------------------------PFMETLEEYP--------NMK----------------------- 45   Thermococcus kodaka...
Q9KD04   77 ------------------------------------NHLENTEQLLKKEEKRTNDQRt---------------------- 98   Bacillus halodurans
Q8TZQ1  108 sekiangepltydekwf-mlqapggffdhtipwngePVTDENGNPIRDFWDRYTELKdkmlaakqkyanlpleeqkvavt 186  Pyrococcus furiosus
O66934   80 irkdpddl-------------------ekeevekliEFTKLNYEKPIYRFERIRELMnkeklnre--------------- 125  Aquifex aeolicus
Q55545   87 tlspveklsleqkvei---lttffeanprtqifpqhRYQQLYEQRQRQGIDWCISHWqpqdfs----------------- 146  Synechocystis sp. P...
5WU7_A  103 -----------ainFMIGYFKDVYS------------------------------YWKSI-DGNILGKFRE--LQ---DE 135  Pyrococcus horikosh...
Q8ZT36  163 -----qdfidlatlFNLLWIDPYIArqnpeiwalrnk------tnytredlkkvlQIHLElIKQVLPVYKK--LA---EQ 226  Pyrobaculum aerophilum
Q9HLU6  399 ---------akvlwFLYDISTPLVEgqlgstwmnstiwamhnqtsfsqrdlteilHYSKWlTGQVIPAFRNdmLGndlGS 469  Thermoplasma acidop...
O83182   49 --------------LTVHMTGSFFQ------------------------------FIQKK-NSPYPYLINN--LL---GS 78   Treponema pallidum
P09961   47 --------------INVHFSGFLLL------------------------------WLEKN-HPEYFEKLKI--MA---ER 76   Dictyoglomus thermo...
O32450   46 --------------VAVHYSGPLLE------------------------------WIRDN-KPEHLDLLRS--LV---KR 75   Thermococcus kodaka...
Q9KD04   99 -------------qNLVQFYKQRYEkl--------------------------kaTFLQW-DRNLLIGFRS--LM---EN 133  Bacillus halodurans
Q8TZQ1  187 nefteqdyidlavlFNLAWIDYNYIistpelkalydkvd---eggytredlktvlYHQMWlLNNTFKEHEK--INlllGN 261  Pyrococcus furiosus
O66934  126 ------elldlqtlNLLAWCGRTLRkdlkdllnkgr--------nytqeekeyvlNKYFEiIKKTLSIYRE--IK---EE 186  Aquifex aeolicus
Q55545  147 ---------dllawHNLIWFDALTIaedrdvrdwyfrq-----ksftlgdrqriiSKQRQiIQGIIPLHRQ--LQ---ES 207  Synechocystis sp. P...
5WU7_A  136 GYVEVITSAATHGYLPLL---------------GR-----DEAIEAQLLNGIKVYEKYFG---RKPRGIWLPECAYRPDg 192  Pyrococcus horikosh...
Q8ZT36  227 GRIELVPVPYSHPLMPLL---------------ADmg--aIYDLKLHVNLSNSLFKRYLG---VTPTGVWPPEQAVNDE- 285  Pyrobaculum aerophilum
Q9HLU6  470 DNVELFTSPFYHPLTPLLlannisgpdgtiqkaSY-----YSDVLAQMNISRGQFHELFG---QWPSGMYAPEFTVSYQ- 540  Thermoplasma acidop...
O83182   79 KRLELLSGGFYQPYLPLL---------------PQ------ADVISQIELLTSTLREHVI---KRPRGCFLEASAWSAA- 133  Treponema pallidum
P09961   77 GQIEFVSGGFYEPILPII---------------PD------KDKVQQIKKLNKYIYDKFG---QTPKGMWLAERVWEPH- 131  Dictyoglomus thermo...
O32450   76 GQLEIVVAGFYEPVLASI---------------PK------EDRIVQIEKLKEFARN-LG---YEARGVWLTERVWQPE- 129  Thermococcus kodaka...
Q9KD04  134 EQCTLMTSAATHAFFPYL---------------KT-----KEAIRAQVRHGIACFEQHFG---KKPLGFWLPECAFSPG- 189  Bacillus halodurans
Q8TZQ1  262 GNVEVTVVPYAHPIGPIL---------------NDfg--wSEDFDAHVKKAHELYKKYLGggvATPRGGWAAESALNDK- 323  Pyrococcus furiosus
O66934  187 GKGSVSTSPYYHPLIPILlnpncvyettpnvkiPDfavsfREDASKHVELAKEKYFEIFG---EHPVYMWPPEASVSNE- 262  Aquifex aeolicus
Q55545  208 GQLEIITSPYGHPILPLLadtniartiqaalalPDprfcwSEDGIRQLQQGKQYYRSTFG---RESRGLWPPGLAVSPA- 283  Synechocystis sp. P...
5WU7_A  193 lwkspstgevkwrkgIEHFLKK--------------------FGIEYFFVEShlidkgpvslrYGNILPAKtk---rSTL 249  Pyrococcus horikosh...
Q8ZT36  286 ---------------VLRLFAN--------------------AGYIWTVTDEd---------vLKATAPGA------SHF 315  Pyrobaculum aerophilum
Q9HLU6  541 ---------------MMQAINEsgaiwsnsaeatlrasginaLGYDFGNGGN-----------VSQMMNLY------TPY 588  Thermoplasma acidop...
O83182  134 ---------------LIPSLVK--------------------AGMEYCLLDYrlfeasdmpatKPAVLEDSskclvaLPY 178  Treponema pallidum
P09961  132 ---------------LVKYIAE--------------------AGIEYVVVDD-----------AHFFSVGLke---eDLF 162  Dictyoglomus thermo...
O32450  130 ---------------LVKSLRA--------------------AGIDYVIVDD-----------YHFMSAGLsk---dELF 160  Thermococcus kodaka...
Q9KD04  190 ---------------VDRILFE--------------------EGIRYTFVDE-----------HAVLTADPtp--hkGSS 221  Bacillus halodurans
Q8TZQ1  324 ---------------TLEILAE--------------------NGWQWVMTDQm---------vLERMGIPYsi---eNYY 356  Pyrococcus furiosus
O66934  263 ---------------ALELYYE--------------------KGINMLATDEv---------iLKNSVERA------SPY 292  Aquifex aeolicus
Q55545  284 ---------------MLQTVAQ--------------------LRFEWLCADEsvlaq--slstSAERSVWL------NSV 320  Synechocystis sp. P...
5WU7_A  250 RPYFLKNG-----IAVFARNRETgiqvwSAKVGYPGD----------------PWYR----------------EFHKRAE 292  Pyrococcus horikosh...
Q8ZT36  316 KLYFVQYGdr--kLYVFFRDKTL-----SDNIGFRYSslspea----aladfvNYLKrvpre------kcsvvVIALDGE 378  Pyrobaculum aerophilum
Q9HLU6  589 IALGPNNTs----VYMFFRDGYI-----SNNWAFNYGnlptwt----avdniiNYLKgvysaipaqyhqrtlvTIGIDGE 655  Thermoplasma acidop...
O83182  179 RELTIDTPaetfyAQLVARYGDTpgtvlIFMLPLDCYqklfft-----hdnasTWFKtfiqyvq---kpnspfRLTHTGE 250  Treponema pallidum
P09961  163 GYYLMEEQgy--kLAVFPISMKL-----RYLIPFAdpe------------etiTYLDkfased-----kskiaLLFDDGE 218  Dictyoglomus thermo...
O32450  161 WPYYTEDGge--vITVFPIDEKL-----RYLIPFRpvd------------ktlEYLHslddgd-----eskvaVFHDDGE 216  Thermococcus kodaka...
Q9KD04  222 APIYSPHG-----IALFPRHTELsakvwSSTLGYPGDvdyrefyrdiaydrewDYIKphvhk------dgiriDTGLKYH 290  Bacillus halodurans
Q8TZQ1  357 RPWVAEFNgk--kIYLFPRNHDL-----SDRVGFRYSgmnqye----avedfiNELLkiqkyny---dgslvyVITLDGE 422  Pyrococcus furiosus
O66934  293 LRYYFREL-----ISVFFRDKTL-----SDLIGFSYHawnaed----avrdfiGRLKkihesv----dfqpvvFVVLDGE 354  Aquifex aeolicus
Q55545  321 YRVPTEDGe----LAMVFRDQQL-----SDLISFHYGryspaq----aaedlmARLLarrpqae--ngqprlvTIALEGD 385  Synechocystis sp. P...
5WU7_A  293 K-SGg-qYWRVTGTKdlgakepYEPeKAME---RVNEHAkhfIGLVLSILESFEs------TEGEKGI------------ 349  Pyrococcus horikosh...
Q8ZT36  379 NpWE---NYPNFGDD-------FLR-VFFQglaQLEKNG---TVKIWKPSDFIKacgneaaELPQREFkyf-------dl 437  Pyrobaculum aerophilum
Q9HLU6  656 N-WMfmsPFAEDGVp-------FLE-DLYT---ALEQNSt--YIHTVTPEQFIN-------QIKNEG------------- 701  Thermoplasma acidop...
O83182  251 I-YK---EPPVCFg--------YIAsNMVRndvLLHKTA----KQLIICSTHAR-------LLYAKMMyv---------h 298  Treponema pallidum
P09961  219 K-FG---LWPDTYRTv------YEEgWLET---FVSKIKe--NFLLVTPVNLYTym----qRVKPKGR------------ 267  Dictyoglomus thermo...
O32450  217 K-FG---VWPGTYEWv------YEKgWLRE---FFDRVSsdeRINLMLYSEYLQ-------RFRPRGL------------ 264  Thermococcus kodaka...
Q9KD04  291 RiTG---HTEEKDL--------YVReWAEK---RVQEHAnhfIGAIHHEIDQHGg------QNFPPYV------------ 338  Bacillus halodurans
Q8TZQ1  423 NpWE---HYPYDGKL-------FLE-TLYKrlsELQEAG---LIRTLTPTEYIQlygdkanKLTPQMMerldftteerve 488  Pyrococcus furiosus
O66934  355 NcWE---YYEENGIP-------FLE-KLYS---TLEKEE---WIETLTLEEAMRk-----eDVKTEVI------------ 400  Aquifex aeolicus
Q55545  386 RtWN---GYENNGFG-------FLQ-QFYQ---QCEQLGrqgLLQLVTVSKFID-------QFPPTQVlaq-------qn 437  Synechocystis sp. P...
5WU7_A  350 -VVAP 353  Pyrococcus horikoshii OT3
Q8ZT36  438 hLDLS 442  Pyrobaculum aerophilum
Q9HLU6  702 -IKLP 705  Thermoplasma acidophilum
O83182  299 nIAMQ 303  Treponema pallidum
P09961  268 -IYLP 271  Dictyoglomus thermophilum H-6-12
O32450  265 -VYLP 268  Thermococcus kodakarensis KOD1
Q9KD04  339 -MVTP 342  Bacillus halodurans
Q8TZQ1  489 aLKVA 493  Pyrococcus furiosus
O66934  401 -ESVK 404  Aquifex aeolicus
Q55545  438 gIPIP 442  Synechocystis sp. PCC 6803
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