5HCI_D 7 CIGMAGSGKTTFMQRLNSHLRAEKTPPYVINLDPAVLRVPYGANIDIRDSIKYKKVMENYQLGPNGAIVTSLNLFSTKI- 85 baker's yeast Q9YDX8 7 VTGTAGAGKSSLVGALADRITSLGANVATLNLDPAAEKLPYDPSVDARDYVSVAELMDK-GLGPNGALVAAVDSLINHV- 84 Aeropyrum pernix O58345 9 FVGTAGSGKTSLTGAFGEYLEEN-YKVAYVNLDTGVKELPYKPDIDVREFVTVEEIMKE-GYGPNGAIVESYD----RLm 82 Pyrococcus horikoshii O28074 8 FTGTAGSGKTYMTKALADWFDLKKLDYLTVNLDPGADFLPYSADIDVREWFTLEDIMGRYNVGPNGAQIIGAD-LVSTLi 86 Archaeoglobus fulgidus P46577 35 VLGMAGSGKTTFVQRLTAFLHARKTPPYVINLDPAVSKVPYPVNVDIRDTVKYKEVMKEFGMGPNGAIMTCLNLMCTRF- 113 Caenorhabditis elegans Q9V3R3 28 VLGMAGSGKTTFTQKLIQHAQ-EKFNPYVVNLDPACREVPYAAHVDIRDTVNYREVMKQYQLGPNGGIVTALNMFTTKM- 105 fruit fly Q8W586 46 VVGMAGSGKTSFLHRLVCHTFDSKSHGYVVNLDPAVMSLPFGANIDIRDTVKYKEVMKQYNLGPNGGILTSLNLFATKF- 124 thale cress O42906 13 VVGMAGSGKTTFMQQLNAHLHSKNKPPYILNLDPAVRNLPYEANIDIRDTINYKEVMKQYNLGPNGGIMTSLNLFVTKF- 91 Schizosaccharomyces p... Q9VU67 20 IIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEPVLSVMELITVEDCMEHLKLGPNGALMHCAEYLADHLe 99 fruit fly O01426 6 VIGAPGAGKSTFCAGLTDIFSQTKRPFLTINLDPANDTMAYAPDVNITEMITVNDVMDRLGLGPNGALKYCIETLGANC- 84 Caenorhabditis elegans
5HCI_D 86 DQV---IRLVeQKkDKf-QNCIIDTPGQIECFVWSASGAIITESFAS-SFPTVIAYIVDTPRNSSPTTFMSNMLYACSIL 160 baker's yeast Q9YDX8 85 --Ld-iREEI-DYySP--DYVVVDTPGQLELFAYRVGGPLVLRGIMG-DYNGVNIFLIDSIFIDNAISLVSALLLASSVA 157 Aeropyrum pernix O58345 83 NKFdyyLKEI-LElESkkDYVLIDTPGQMETFLFHEFGVKLMENLPY----PLVVYLSDPEILRKPTDYCFVRFFALLID 157 Pyrococcus horikoshii O28074 87 DDI---RDEI-QLsSS--EYVLIDTPGQLELFTLRESSRVLVNALN--PERSVMVYLFDPVVSKTPSGFLSMLFMASSAV 158 Archaeoglobus fulgidus P46577 114 DKV---IELInKRsSDf-SVCLLDTPGQIEAFTWSASGSIITDSLAS-SHPTVVMYIVDSARATNPTTFMSNMLYACSIL 188 Caenorhabditis elegans Q9V3R3 106 AQF---AELVrRAgERghKWCVIDTPGQIEVFNWSASGSIITEGLAT-MFPTIVVYVMDVERSACPTTFMSNMLYACSIL 181 fruit fly Q8W586 125 DEV---VSVIeKRaDQl-DYVLVDTPGQIEIFTWSASGAIITEAFAS-TFPTVVTYVVDTPRSSSPITFMSNMLYACSIL 199 thale cress O42906 92 DQV---LKILeKRaPTv-DHILIDTPGQIEIFQWSASGSIICDTLAS-SWPTCIAYVVDTPRATSTSTWMSSMLYACSML 166 Schizosaccharomyces p... Q9VU67 100 DWL---LPALrKL-SAtyNYFLFDCPGQVELYTHHNAMARIFERLEReRYSLVTVNLIDSHYCSEPAKFIATLLMALNTM 175 fruit fly O01426 85 NWL---LQKIeAN-HK--KYLIIDCPGQLELYKSEGELWKVIRFLEKsGVRLCALHLADSLYCSDPSKFISVALSTLATM 158 Caenorhabditis elegans
5HCI_D 161 YKTKLPMIVVFNKTDVCK-----ADFAKEWMTDFESFQAAIKedQd--------GYMSSLVNSMSLMLEEFYSQlDVVGV 227 baker's yeast Q9YDX8 158 VRLGLPQVNAVSKADMLLpe--vREEVIPRLGEPGFLEFLLEkdKty------eGAGKALAEELARAIETTGFIgEVLQA 229 Aeropyrum pernix O58345 158 LRLGATTVPALNKVDLLKee--qLEKHRKYFEDLDYLMGRLKfdPsm------qGL---MAYKMCSIMMEVLPPiRVLYL 226 Pyrococcus horikoshii O28074 159 FRLEIPQVLVLSKSDILSer--eLERIVEWSEDPETLYDSLNl------------eRKTLNLELFLLLKEAGLFrPLIPA 224 Archaeoglobus fulgidus P46577 189 YRTKLPFIVVFNKADIVK-----PTFALKWMQDFERFDEALEdaRs--------SYMNDLSRSLSLVLDEFYCGlKTVCV 255 Caenorhabditis elegans Q9V3R3 182 YKTRLPFLVALNKIDLKD-----CGFVMDWMTDFEAFQEAQEeeH---------SFVSNLTRTMSLTLDTFYENlRTCGV 247 fruit fly Q8W586 200 YKTRLPLVLAFNKTDVAD-----HKFALEWMEDFEVFQAAIQsdN---------SYTATLANSLSLSLYEFYRNiRSVGV 265 thale cress O42906 167 YKAKLPLIIVYNKCDVQD-----SEFAKKWMTDFEEFQQAVTkdEgmssegatsGYMGSLVNSMSLMLEEFYRHlDFVSC 241 Schizosaccharomyces p... Q9VU67 176 LRMSLPHVNVLSKADLLKkhetkLHFNVDYYTDVLDLKYLLDklDddp----amRKYRKLNAAICSMVEDYALV-SFQLL 250 fruit fly O01426 159 VTMEMPQVNCLSKADLFSed---gtYDLEFFSHLPDVNRLLDllNevp----glEKYRKLNEAICGVISDFDLV-SFVPL 230 Caenorhabditis elegans
5HCI_D 228 SSFTGDGFDEFMQCVDKKVDE 248 baker's yeast Q9YDX8 230 SVLEPETVTLLAAKAQQILAG 250 Aeropyrum pernix O58345 227 SAKTREGFEDLETLAYEHYCT 247 Pyrococcus horikoshii O28074 225 SALTGYGMEDIYDAIQEIFYG 245 Archaeoglobus fulgidus P46577 256 SSATGEGFEDVMTAIDESVEA 276 Caenorhabditis elegans Q9V3R3 248 SAKTGVGFTQLLTKILESVDE 268 fruit fly Q8W586 266 SAISGAGMDGFFKAIEASAEE 286 thale cress O42906 242 SSVTGEGMDDFLEAVKAKVKE 262 Schizosaccharomyces pombe 972h- Q9VU67 251 DVFSTDSMLRLRNHIDKANGY 271 fruit fly O01426 231 AVENKESMMKVIQMVDAANGF 251 Caenorhabditis elegans
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",