6JIB,3NGL


Conserved Protein Domain Family
THF_DHG_CYH_C

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pfam02882: THF_DHG_CYH_C 
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Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
Statistics
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PSSM-Id: 397150
Aligned: 82 rows
Threshold Bit Score: 159.937
Threshold Setting Gi: 81551574
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6JIB_B 143 HVINVGRMCLD--QY----SMLPATPWGVWEIIKR-TGIPTLGKNVVVAGRSKNVGMPIAMLLHTDgaherpggDATVTI 215 human
Q6ADF1 123 HPTNLGRLVLN--VNrpitTPLPCTPRGVIELMLR-HGIDLAGKDVVVVGRGVTVGRSIGALLTRRe------vNATVTL 193 Leifsonia xyli subsp....
Q8G5L6 123 HPYNLGELVLH--VRgdisTPLPCTPRGVLELLDA-YDIDLNGKEVCVLGRGITIGRTIGLMLTRNa------vNATVTL 193 Bifidobacterium longu...
O51057 128 SFVNLGKMILGdkKG-----FIPCTALAVLKILRD-EGIKTLGKTVVVVGRSPLVGRPISILLSSKp------yDATVIV 195 Borreliella burgdorfe...
Q9RW02 134 SPANLALIAAGrePE----ALLPPTPRSVRFLLRHaLGDDLRGLRVAVIGPGRTVGRPLLFMLNNK--------GATVTL 201 Deinococcus radiodura...
Q6L046 118 TSYNLGNLYLK--NE----FIAPATARAVVDILDY---INIKSGNVAIINRSPVVGRPLSMMLLNR--------DFTVTV 180 Picrophilus torridus ...
3NGL_C 117 SPYNQGLIALN--RE----FLVPATPRAVIDIMDY-YG--YHENTVTIVNRSPVVGRPLSMMLLNR--------NYTVSV 179 Thermoplasma acidophilum
Q9X288 113 NPANLGLLLYD--EE----IFPPCTAEAAVRILE--RETNLSGKRVTVVGRSVTVGKPLALMLLKKg------rDATVTV 178 Thermotoga maritima MSB8
Q98QV3 116 NPENEKAFYEN--RE----CIIPATARAIWTFLKF-HKISVENKKVFVVGQSRLVGKPISQFLKNN--------NAIVRV 180 Mycoplasma pulmonis U...
Q6KID0 116 SEKNSKNLYSG--KS----CIQPATARGIIDLIKE-YNFTIKDKKVYVIGESNLVGKPIKELFKQA--------GAIVKS 180 Mycoplasma mobile 163K
6JIB_B 216 SHRYTpkEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVhdpvtAKPK-LVGDVDFEGVRQK-AGYITPV 293 human
Q6ADF1 194 THTGT--KSLDEHLRSADVIVAAAGVPGLVSAENVKPGAIVLDVGVSRVedpetGKSR-VAGDVA-ADVAGV-ASWISPN 268 Leifsonia xyli subsp....
Q8G5L6 194 CHTGT--RDVADHMRRADVIVAAMGSAGFVTPDKIKDGAVLVDVGVSRVydeeaGRYR-IKGDVD-KACYDK-ASAYTPN 268 Bifidobacterium longu...
O51057 196 CHSKS--IYLDVYLRQADIVISAVGKPRLIDKSMLCGKPYVIDIGISEIe---tDNGKiLSGDTDFDNIKEC-VKFITPV 269 Borreliella burgdorfe...
Q9RW02 202 CNEHT--RDLAAVLAAQDAVVVAVGKAGLLRPEQVQPEHVVIDAGINVQ----------ESGDMVGDALPELpVRAQTPV 269 Deinococcus radiodura...
Q6L046 181 CHSRT--VNINEITRSSDIVVVAVGKPNFLDRSYVSDKNIIIDVGINYL------NGK-TCGDADYENIKDY-VNAITPV 250 Picrophilus torridus ...
3NGL_C 180 CHSKT--KDIGSMTRSSKIVVVAVGRPGFLNREMVTPGSVVIDVGINYV------NDK-VVGDANFEDLSEY-VEAITPV 249 Thermoplasma acidophilum
Q9X288 179 CHSRT--VNLEEITKNSDIVVVAVGRAHFLKKNMVKEGAIVIDVGINYV------DGK-LQGDVD-PSVEEI--ARVTPV 246 Thermotoga maritima MSB8
Q98QV3 181 FDKST----GLKGTEEADILIVATGVAQLIKAENIKENSILIDVGFSKI------NNK-IYGDLDIESIKEK-ALKYTPP 248 Mycoplasma pulmonis U...
Q6KID0 181 FNINT----GIKGSEEADILIVAAGHPNLVKPENVKNNSIVIDVGINSIg---eNDKMiVTGDVDFSNVKTK-VKAISPV 252 Mycoplasma mobile 163K
6JIB_B 294 PGGVGPMTVAMLMKNTIIAAKKVL 317 human
Q6ADF1 269 PGGVGPMTRALLLQNVVESAERAL 292 Leifsonia xyli subsp. xyli str. CTCB07
Q8G5L6 269 PGGVGPMTRAMLLANVVEMAERHA 292 Bifidobacterium longum NCC2705
O51057 270 KGGIGPVTVLMLMFNTIKAHLINN 293 Borreliella burgdorferi B31
Q9RW02 270 PGGVGPLTSALMYQNLVRGVKLQR 293 Deinococcus radiodurans R1
Q6L046 251 PGGVGPVTATDIFENFINGLKYQI 274 Picrophilus torridus DSM 9790
3NGL_C 250 PGGVGPITATNILENVVKAAEFQK 273 Thermoplasma acidophilum
Q9X288 247 PGGVGQVTTALLFEHVVRAAERQR 270 Thermotoga maritima MSB8
Q98QV3 249 IGAIGPVTVLSLFENLYEIILKKK 272 Mycoplasma pulmonis UAB CTIP
Q6KID0 253 PGGVGPMTVISLFKNLIEIFEKYL 276 Mycoplasma mobile 163K
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