1Y1U


Conserved Protein Domain Family
STAT_bind

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pfam02864: STAT_bind 
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STAT protein, DNA binding domain
STAT proteins (Signal Transducers and Activators of Transcription) are a family of transcription factors that are specifically activated to regulate gene transcription when cells encounter cytokines and growth factors. This family represents the DNA binding domain of STAT, which has an ig-like fold. STAT proteins also include an SH2 domain pfam00017.
Statistics
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PSSM-Id: 397134
Aligned: 49 rows
Threshold Bit Score: 115.362
Threshold Setting Gi: 0
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1Y1U_A       209 KQPPQVLKTQTKFAATVRLLVGGKLNVH---MNPPQVKATIISEQQAKSLLK------------NENTRNECSGEI--LN 271 house mouse
XP_001946645 340 TQPPQVLKTNTRFVAEVRLLIGGKLNIH---MTSPVVKVSIVSESQANQIIG------------RNKPDGESCGEI--LN 402 pea aphid
XP_016033862 346 KQPPQVMKTNTRFAASVRWLIGSQLGIH---NNPPTVECIIMSEIQSQRFVTrnt------qmdNSSLSGQSSGEI--QN 414 Drosophila simu...
XP_015789254 178 KQPPQVIRTNKQFQASIRSLIGGLFNSNntlFNSSSVSVSILSESQAILMISq----------eDNSLFSDASGEI--SN 245 two-spotted spi...
XP_015793452 179 KQPPQVLKTNTRFPSTVRSLIGGLLSSNttiHHSPIVRASILNESQARMLMQs----------qDNTLVDLTSGAI--LN 246 two-spotted spi...
Q16V47       328 KQPPQVMKTNTRFAATVRLLIGNTLNIR---MSNPLVRVSIISEAQAQATQQ------------SNKASEQSCGEI--MN 390 yellow fever mo...
Q7QDU4       296 NQPPQVMKMNTRFCATVRLLIDNALIMK---IGNPKVTVSIISETQAQQIQS------------TNAAADFSAGEI--EN 358 African malaria...
EFN82765     338 KQPPQVMKTNTRFTSTVRLLVGGKLNVH---MTPPQVRVYIVSETQANALLK------------SDKMKNDNSGEI--LN 400 Jerdon's jumpin...
EDO42973     361 KHAPQILKIGTKFCATLRHLIGGKLNAH---VHPPEVECFIVPE---KFLQKn-----------KDKIVRSILGKStiLN 423 starlet sea ane...
XP_004994980 341 QQPPQVLKTQSRFQATVRLLVGPSLTLH---LNPPEVSAHIVNERNVREIRQttllqeggqsmqLPLPDPPSSGDI--LN 415 Salpingoeca ros...
1Y1U_A       272 NCCVMEYHQAtGTLSAHFRNMSLKRIKRADR--RGAESVTEEKFTVLFESQFSVGsnELVFQVKTLSLPVVVI 342 house mouse
XP_001946645 403 CTGKMEYQPVqRHLSTNFRSMQLKKIKRTEK--KGTESVMDEKFSILFSSKFFIGn-ELQFEVWNLSLPVVVI 472 pea aphid
XP_016033862 415 ASSTMEYQQNnHVFSASFRNMQLKKIKRAEK--KGTESVMDEKFALFFYTTTTVN--DFQIRVWTLSLPVVVI 483 Drosophila simulans
XP_015789254 246 SESSLEYQSTtGQSIAHFEHLILKKINRTEK--KGTESVTDEKFALLFQATIKLG--ELVFHVKALSSPLVVI 314 two-spotted spider mite
XP_015793452 247 RESNLQWQPTtKQSIANFRTLILKKINRTEK--KGTESVTDEKFALLFQAVIKLAagELVFYVKTLSLPLVVI 317 two-spotted spider mite
Q16V47       391 NTGNLEYNETtKQLSVSFRNMQLKKIKRAEK--KGTESVMDEKFALLFQSSFAVGhgDLVFSVWTISLPVVVI 461 yellow fever mosquito
Q7QDU4       359 NIGNLQYQLSnKFLAN-FSNMRLKKINRGNR--KLNKLVVDEKFALLFQSSFTLEqeELTVTVWTLSLPAVVI 428 African malaria mosquito
EFN82765     401 NTGTMEYHQTtRQLSVSFRNMQLKKIKRAEK--KGTESVMDEKFSLLFQSQFSVGggELVFQVWTLSLPVVVI 471 Jerdon's jumping ant
EDO42973     424 YKKAMEYSQRyNSFSVEFKNLNLTKTDREGG--KKDETVCEKKRSLLFYTELTIG--QDRFPLLATSFPCVVT 492 starlet sea anemone
XP_004994980 416 SRKAMGVQPGnNALQVGFKTLSLRKIKRTDKseKIDHTVTEQKFSICFRVTVTLPggDSVYLLQELSLPVVVV 488 Salpingoeca rosetta
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