5CLW,1CLV,1G94,1CGT,1TCM,1CYG,1QHO,4LPC


Conserved Protein Domain Family
Alpha-amylase_C

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pfam02806: Alpha-amylase_C 
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Alpha amylase, C-terminal all-beta domain
Alpha amylase is classified as family 13 of the glycosyl hydrolases. The structure is an 8 stranded alpha/beta barrel containing the active site, interrupted by a ~70 a.a. calcium-binding domain protruding between beta strand 3 and alpha helix 3, and a carboxyl-terminal Greek key beta-barrel domain.
Statistics
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PSSM-Id: 397096
Aligned: 242 rows
Threshold Bit Score: 31.9231
Threshold Setting Gi: 251764781
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5CLW_A       571 YVSekhegNKIIAF------ER-AG-----------------LLFIFNFHPsKSYTDYRV-GT-AL-PGK--FKIVL-DS 620  human
WP_012369718 891 YLTfkdvpEQVVAY------QL-SDdapq---------qktdLYVVHN----AKRQAVKM-TL-PK--GT--WSVIV-DG 943  Exiguobacteriu...
O33840       762 HLEflpggRRIVAF------ML-KDhaggd--------pwkdIVVIYNGN--LEKTTYKL----PE--GK--WNVVV-NS 815  Thermotoga mar...
Q6MC69       581 WENd----NKFIAFslniphEG-PD-----------------LYVAFN----ASHVVLTV-TIpPArQGMh-WVWLV-NT 631  Candidatus Pro...
P73608       615 WSAd----SRVLAFmlcgrhAK-GGrvk-----------dnqIYVAMNMHYeSLWFELPA----PPvGTT--WHVFA-NT 671  Synechocystis ...
Q84YG5       683 YNEe----SRFLAF------ML-HDgng------------gdIYLAFNAHHfSIKTAIPS----PPrNRS--WYRVV-DT 732  potato
Q9M0S5       680 WDNs---eSKFLAF------TL-HDgig-----------grdIYVAFN------AHDYFVkALiPQpPPGkqWFRVA-DT 731  thale cress
AAK42273     628 WSSp----TQLVIF------VL-EGsvmdeinmygeriaddsFLIILNANPnNV--KVKF----P--KGK--WELVI-SS 685  Saccharolobus ...
WP_001288328 414 FAT-----KNVLAF------SR-GDsvnin-------hsphdGLVIINKGNeEVEGTWPN----KLqPGI--YKNMGsNS 468  Enterobacteria...
Q47RP6       483 WADa---pQNVLAF------RRePG-----------------FTCAVNFGAdPV-------TL-PF-EGE----VVL-SS 522  Thermobifida f...
5CLW_A       621 DAAeygghqrldhstdFFSEAFehngrpySLLVYIPSRVALILQNV 666  human
WP_012369718 944 KTAg------------MKTLKKvs------gSVTVDPLSSYVLKK- 970  Exiguobacterium sibiricum
O33840       816 QKAg-----------tEVIETVe-------gTIELDPLSAYVLYRE 843  Thermotoga maritima MSB8
Q6MC69       632 HNVap---------gdFFEESCrkr--vnSNTLKIPSYTSIALKAE 666  Candidatus Protochlamydia amoebophila UWE25
P73608       672 GAQppe--------diHPPGQEppl--ssQSSLLIGDRSVVILLAK 707  Synechocystis sp. PCC 6803
Q84YG5       733 NLKsp---------ddFVTEGVsg----iSKTYDVAPYSAILLEAK 765  potato
Q9M0S5       732 NLEsp---------ddFVREGVag----vADTYNVAPFSSILLQSK 764  thale cress
AAK42273     686 YLReik--------peERIIEG-------EKELEIEGRTALVYRRI 716  Saccharolobus solfataricus P2
WP_001288328 469 VNIiinntrkiippgkVFTLRGg------TLNINIPGRSALLLGKT 508  Enterobacteriaceae
Q47RP6       523 GPVeqd-----------------------gtHLVLPGDTAVWLRQ- 544  Thermobifida fusca YX
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