1XUQ,6EX4,4L2C,3TQJ,3H1S,1MY6,1UES,4YET,3JS4,1MA1,1P7G,3AK3,4FFK,1B06,4C7U,3DC6,1KKC,4F6E,3TJT,3MDS


Conserved Protein Domain Family
Sod_Fe_C

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pfam02777: Sod_Fe_C 
Click on image for an interactive view with Cn3D
Iron/manganese superoxide dismutases, C-terminal domain
superoxide dismutases (SODs) catalyze the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the Mn/Fe-binding family is one. In humans, there is a cytoplasmic Cu/Zn SOD, and a mitochondrial Mn/Fe SOD. C-terminal domain is a mixed alpha/beta fold.
Statistics
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PSSM-Id: 397070
Aligned: 870 rows
Threshold Bit Score: 82.4694
Threshold Setting Gi: 189184923
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XUQ_A       107 PVGELATAIEAKFGSFDAFKEEFAKAGATRFGSGWAWLVVN-N-GELEVTSTPNQDSplte-gktPVIGLDVWEHAYYLN 183 Bacillus anthracis
O84296        96 PRHELLKLIEKFWGSFDNFLKNFITSSAAVQGSGWGWLAFCpQkQELMVQTTANQDPleattgmiPLLGVDVWEHAYYLQ 175 Chlamydia trach...
XP_001845445 107 PSKALEASLKHNFYSMEDFKALVRGAALNVQGSGWVWLGWDkDrKLLRIAACANQDPleattglmPLLGIDVWEHAYYLQ 186 southern house ...
Q17B12       106 PSKALESGLKQNFYSKEDFKQLMRDTALSVQGSGWVWLGWHkPsKTMKIAACCNQDPleattgllPLLGIDVWEHAYYIQ 185 yellow fever mo...
XP_015795062 116 PEGLLLDSIKSSFGSFDNLKSLMNAAAVGVQGSGWAWLGYNpVnKNLQVASCPNQDPlqattgliPLLGIDVWEHAYYLQ 195 two-spotted spi...
Q17BT9       111 PSAELKKLLERDFHGLENFKKEMKAAAVAVQGSGWAWLGYNqKtKALQVAACPNQDPlqattglvPLLGIDVWEHAYYLQ 190 yellow fever mo...
XP_002403511 114 PTGDLLEAIKKDFGSFEALKAQMSARAVGVQGSGWAWLGYNpKtQRLQVATTGNQDSlwdteglvPLFTIDVWEHAYYLQ 193 black-legged tick
XP_002427902 111 PSNELSCAINASFGSLDKMKDLMSQMAVAVQGSGWAWLGYSpItKSLQLAVAKDQDSlfamtgliPLLPIDVWEHAYYIQ 190 human body louse
9_pfamImport   1 PSDELTKAICTTFGSFDEMKKQMMTMTNAIQGSGWGWLGLNpLtKKLQLATTGNQDLlrdttgliPLLGIDVWEHAYYLQ 80 
BAH70786     113 PSDDLNKALIQNFGSCDEFKKQLATASIAVQGSGWGWLGFNpQtKKLAVISCANQDPlfpttgliPLFGIDVWEHAYYLQ 192 pea aphid
1XUQ_A       184 YQNRRPDYIGAFWNVVDWNAAEKR 207 Bacillus anthracis
O84296       176 YKNARMDYLKSFPSIINWDYIENR 199 Chlamydia trachomatis D/UW-3/CX
XP_001845445 187 YKNDRAQYFDALWEIINWKEVSKR 210 southern house mosquito
Q17B12       186 YKNDRAKYFDALWEIIDWKVVSNR 209 yellow fever mosquito
XP_015795062 196 YKNVRPDYVKAIWNVINWRDVGDR 219 two-spotted spider mite
Q17BT9       191 YKNLRPNYVDAIWDVVNWKDVSER 214 yellow fever mosquito
XP_002403511 194 YRNVRPDYVKAIWDIANWNNVAER 217 black-legged tick
XP_002427902 191 YRNVRAEYVKSFWNIVNWNKVSER 214 human body louse
9_pfamImport  81 YKNVRADYTKKIFDIVNWHDVNNR 104
BAH70786     193 YKNVRADYVNAIFEVVDWDAVSKR 216 pea aphid
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