Conserved Protein Domain Family
MOSP_N
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pfam02707: MOSP_N 
Major Outer Sheath Protein N-terminal region
This is a family of spirochete major outer sheath protein N-terminal regions. These proteins are present on the bacterial cell surface. In T. denticola the major outer sheath protein (Msp) binds immobilised laminin and fibronectin supporting the hypothesis that Msp mediates the extracellular matrix binding activity of T. denticola.
Links
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Statistics
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PSSM-Id: 280810
Aligned: 5 rows
Threshold Bit Score: 313.283
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O83619       181 LWTEISIKDLEVNFQTK-----------------KPGEPFTLVTEETAIEATLHCFGAYMTIGTAPLFRANFAQLWKPFL 243 Treponema pallidum
O83994         1 MWAELRLKDLTVDFESP-----------------RPGQAFTLKKPKASFEATLHCYNAYLTIGKDPNCFINFAQLWDPFV 63  Treponema pallidum
O83629        84 VWAQLQLKDLAVELASS-----------------KSSTALSFTKXTASFQATLHCYGAYLTVGTSPSCVVNFAQLWKPFV 146 Treponema pallidum
1_pfamImport   1 LYAELKVADLQADLSQG-----------------KAGFAV---KRKGKVEATLHCYGAYLTIGKNPTFLTNFARLWKPWV 60 
O83055        97 IWVELSLKGLKVDFESAlgsgtadpsmttrspflKSG------RSDFSLEATLHLYDVSFSVGKDPVFPSNFAQLWTPFI 170 Treponema pallidum

O83619       244 ADLYKEEEVRFAPGFDGIGGRLGYRAQNVGSSGVSLDICFLSFASNGSWDAPAPapappgg------aaeealHSKYGFG 317 Treponema pallidum
O83994        64 TSDYKQEDVRYAPGFGGYGGKLGYRAQDIGGSGIGLDVGLLSFASNGMWDSGTA-------------------HSKYGFG 124 Treponema pallidum
O83629       147 TRAYSEKDTRYAPGFSGSGAKLGYQAHNVGNSGVDVDIGFLSFLSNGAWDSTDTt------------------HSKYGFG 208 Treponema pallidum
1_pfamImport  61 TAQYQEDAVQYAPGFGGLGGKVGYRAQDIGGSGVSLDVGFLSFASNGAWDSTDPt------------------HSKYGFG 122
O83055       171 TTSYESRSVKYAPGFGGVGGKIAYQARNISNSGITFNCA-LSFSSNGIWKSAPSvtskvkgkgtnsrrmpadpHSKYGLG 249 Treponema pallidum

O83619       318 ADATLSYAPWKRELVRAEVAASATLGKGYKRVSHKQKRHYRQNDVLWNAGARITLTPLSDFKVVLALDMGN 388 Treponema pallidum
O83994       125 ADATLTYTHHRAERIKMELAGNATLEPQYTTGTEQGKNNEQKNRLLWSAGGRLTLTPGYGFRLVLALDVGN 195 Treponema pallidum
O83629       209 ADATLSYGVDRQRLLTLELAGNATLEQHYRKGTED-STNENKTALLWGVGGRLTLEPGAGFRFSFALDAGN 278 Treponema pallidum
1_pfamImport 123 ADLKLMYARAGHPLCTVELASNVTLEDGYLIGAQKDANNQNKDKLLWNVGGRLTLEPGAGFRFSFALDAGN 193
O83055       250 TEFTLVYARKGREQVRLEAASCATLSAGYRTGPDQ-THHQNKDTVLWNVGARLTLSPGAGFKIVCAFDAGT 319 Treponema pallidum
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