2DF4,3H0M,3AL0,3KFU


Conserved Protein Domain Family
GatC
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pfam02686: GatC (This model is not part of the current CDD release)
Glu-tRNAGln amidotransferase C subunit
This is a family of Glu-tRNAGln amidotransferase C subunits. The Glu-tRNA Gln amidotransferase enzyme itself is an important translational fidelity mechanism replacing incorrectly charged Glu-tRNAGln with the correct Gln-tRANGln via transmidation of the misacylated Glu-tRNAGln. This activity supplements the lack of glutaminyl-tRNA synthetase activity in gram-positive eubacterteria, cyanobacteria, Archaea, and organelles. This entry includes the C subunit of the bacterial/archaeal aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferases and eukaryotic Glu-tRNAGln amidotransferases (GatC).
Links
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Statistics
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PSSM-Id: 515111
Aligned: 629 rows
Threshold Bit Score: 33.6503
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2DF4_C         22 PEETEEMANTLESILDFAKQNDSADTE-GVEPTYHVldlq--nvlrED--K--AikgIPQEL-ALKNAKETEDGQFKV 91  Staphylococcus a...
Q73Q67         26 EQEEARLSGQVNNLVGYFEILDKFA-DsSLDSSMYAkhse--tdlrSSevKegL-----AQSdLKKMTSEYMDNYFRV 95  Treponema denticola
WP_020965010   26 kEESEVLSQQINRLIGYFKILDKFA-DpDTGNSMYAaqde--tslrTDeiKegV-----RQIdLKKMTAEYMDNYFRV 95  Treponema pedis
WP_011994658   21 VSDTEKLKKDLQKIIDYFEILSEVNTE-NIEPMYTPieep--feprIA--N--PttnenINE-IIENFPEKVDRLIKV 90  Fervidobacterium
WP_015869244   23 DEERKKLMEELEKILNYMSTLDEVNVD-DIEEMVSPiens--mtprED--R--ArkfehIDS-LIELFPKKEGRYLKV 92  Kosmotoga
55_pfamImport   1 EDERIELKKDIEEILQYMTLLDGVDp--DAEEMVTPveks--leprEDelVefK-----ESRlIRDLFPETEGSYLKV 69 
Q9WY94         22 EDQRESLMKDFQEILDYVELLNEVDVE-GVEPMYTPveds--aklrKG--D--PrffemRDL-IKKNFPEEKDGHIKV 91  Thermotoga marit...
WP_013932368   22 DEQRKSIQKDMNEILQYMELLNEVDVS-NVEPMYTPvees--atlrED--E--VkpfenLHL-LRSNFPKERSGHIVV 91  Pseudothermotoga...
3AL0_C         23 EDQRESLMKDFQEILDYVELLNEVDVE-GVEPMYTPveds--aklrKG--D--PrffEMRDL-IKKNFPEEKDGHIKV 92  synthetic construct
WP_014295607   23 EEEKEIIKKDLEEILNYMNQIDEVITE-NIEPMFSPvenilknvfhED--K--EkvseyIEN-IIKEYPNKKDNLLKV 94  Marinitoga
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