8I03,8BPA,8BPA,8I03,8I03,8IFG,6XAW,8I03


Conserved Protein Domain Family
PAH
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pfam02671: PAH (This model is not part of the current CDD release)
Paired amphipathic helix repeat
This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions.
Links
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Statistics
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PSSM-Id: 515097
Aligned: 327 rows
Threshold Bit Score: 30.4639
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8I03_A         368 EAYNSFLDILKSYQHD--QRPIQLVYFQVSQLFAEAPDLLEEFKRFL 412  fission yeast
XP_007410013   775 EVWHEFLRVLELYNQT--IIDFKTLVDRVSVYIGDNDELLDDFKGFV 819 
ESK84084       451 EIYEEFLKLLSLYSKE--IIDVKTLLDRTGAFF--DGDLLEEFKELV 493 
XP_001829269   540 EVYEEFLKLLSLFSKD--IIDAKTLIERAKVFL-GDENLMAEFKDLI 583 
XP_003037381   512 EMYEDFLKTLTLFSKD--IFGVKDLIDRAKVFL-GDGDLLAEFKELL 555 
XP_001874054   495 EVYEEFLKLLGLFSKD--IFDVNTLIERTRVFL-GDGELMSEFKDLV 538 
XP_009648152   655 TSYNEFLKVCNLFSQQ--IIDRPTVYQKGSVFLAANPELLSFWKQFL 699 
XP_008089532   650 TAFNEFLKVCNLFSQS--IIDRNTVFHKGSVFFAANPELMGFWKAFL 694 
72_pfamImport    1 EDYHAVLDIMVNFNKIdtV-VTEDIIDEVKRIVGNHPKILEEFNFFL 46  
CCO33630        22 WVFDAFVVVLSEYRKQ--QIDIDDLMTHMRAIFSSHEDLFDLFCRFL 66
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