2GVI,3D00


Conserved Protein Domain Family
FmdE

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pfam02663: FmdE 
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FmdE, Molybdenum formylmethanofuran dehydrogenase operon
This entry represents the FmdE protein that is encode by the molybdenum formylmethanofuran dehydrogenase operon. FmdE does not co-purify with the molybdenum isozyme that is formed by FmdC and FmdB. The domain is typically found as a single copy, but is repeated in some sequence two to three times. It is also common place to find this domain co-occurs with a zinc-beta ribbon domain, suggesting that is may bind nucleic acid and be involved in transcription regulation.
Statistics
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PSSM-Id: 396986
Aligned: 167 rows
Threshold Bit Score: 49.1037
Threshold Setting Gi: 509084745
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2GVI_A            16 FHGHKCPYXPXGYRAGSYALKIA------GlekekDHRTYLLSEXSpedxnGCFNDGAQAATGCTYGK------------ 77   Thermoplas...
O26770           667 FHDHACPGVSPGYLITEYIFNNYpl--------keDENYIYLGNTI-----YCKDDAIVYRLGVSPGQ------------ 721  Methanothe...
WP_023991716     287 YHGHVCLGTISGQAMVSLLLKYFppgvygD-----DGELEATSYRAigvpgNSDDDAFGYSLDLTPGKrsyvgyfteeds 361  Methanobac...
O27400           275 FHGHMCLGTISGYAMSKTIYMYYppiqdwSt----GSPIEITSYVTigvpgGSDDDALILALDNTPGKrsylgfdttgag 350  Methanothe...
O26770           287 FHGHMCLGTISGYAMSLTLLKYYppvmdfTn---pGSPGEITSYVTvgvpgDSDDDSLLMFLDTTPGKggsysgfnttat 363  Methanothe...
Q2FQA8           193 FHDHLCPGVTSGYMIIKYIQKNLp-----------iTNQSAETYIDigcpnWCKEDAFQMIWDSTPGK------------ 249  Methanospi...
CAZ98579         269 FHGHLCDGLVVGHLALQEALGELyqdgpiD-----RTNTRIVSQPS-----PCLTDAAIYDTGARYQF------------ 326  Zobellia g...
jgi:TOPB45_0891   72 FHGHLCDGLVIAYIEIKEVLKLLfpdgivD-----KTDLIAVSKNG-----PCWVDAVSYLTGARINF------------ 129  Thermodesu...
BAF72368          70 AHGHLCDGLVLAYVELSNTLPKLfadgviD-----RTDLRVVAKNS-----PCLVDTSGLMSGARINH------------ 127  Sulfurovum...
NZAGRC:Abm4_1108 301 FHGHICEGTLGGYTITKALLQYYppiqetGvg--nQSPGDITSYKIlgvpgDSANDAVLFFLDATSGKrsyigfnttstg 378  Methanobre...
2GVI_A            78 ------------------GLFSLLG-------------YGKLAL--ILYRP-----GRK-AIRVHVRnsfxdelstrasd 118  Thermoplas...
O26770           722 ------------------GTYFNLRvpgtendpeneyaYGGNIE--GILVIwdnknKVGrAVVIDFKwpqfdtsdcatnd 781  Methanothe...
WP_023991716     362 v-----vgfirwcastnlGTLIIMK-------------FNEDVVtqLFKQEtgitaYSGiAAELLFNswli--------- 414  Methanobac...
O27400           351 aed-smvgfirwnsrtntGTLVVMK-------------FDQQALidTYKREtgvsmV----QELKFNawlv--------- 403  Methanothe...
O26770           364 gadtnlvgfirwnpntlkGDLIVMK-------------FDKEALrrQFQQQtg------knTELEFNawli--------- 415  Methanothe...
Q2FQA8           250 ------------------NSMFVMAlspdde-aalkakYGTRPA--GIIIRwndaaKKGkGVALGFDfdtiseevgvanw 308  Methanospi...
CAZ98579         327 ------------------NTFYVSK-------------DIDGLF--TVQRI-----DTQkAVTVRMNqgvkpgeidklga 368  Zobellia g...
jgi:TOPB45_0891  130 ------------------KTLRIDN-------------SIGDGF--IIQRI-----STGeTYQVHLKpgvfpeemsklea 171  Thermodesu...
BAF72368         128 ------------------RTLSLDN-------------SLGGSF--IVQKI-----STGeTYKVELAdtgfikalknkek 169  Sulfurovum...
NZAGRC:Abm4_1108 379 aks-nmiafirwndktnnGTIVVME-------------YNSKKNkaLFEKEtg-ikGNGsLEQLKYNtwwi--------- 434  Methanobre...
2GVI_A           119 ffryrkq-----gyepseipagaidpvlewiSSLEDE 150  Thermoplasma acidophilum
O26770           782 akre----------kqiagfislykgeipsyMTAPPV 808  Methanothermobacter thermautotrophicus str. Delta H
WP_023991716     415 ----------------------------dklENDPDS 423  Methanobacterium sp. MB1
O27400           404 ----------------------------kkvTENPAS 412  Methanothermobacter thermautotrophicus str. Delta H
O26770           416 ----------------------------aklKQDPTS 424  Methanothermobacter thermautotrophicus str. Delta H
Q2FQA8           309 tgp-------------swapklvqdigmmdyIDKPES 332  Methanospirillum hungatei JF-1
CAZ98579         369 lavkgel-----ppceldklrkmeddftetlLSTDPK 400  Zobellia galactanivorans
jgi:TOPB45_0891  172 kikklrfegksvdpedidrlekmaedlikklLNTPPT 208  Thermodesulfobacterium geofontis OPF15
BAF72368         170 -------------------eirtkqkkgekiTPKDID 187  Sulfurovum sp. NBC37-1
NZAGRC:Abm4_1108 435 ----------------------------nriYKNPAS 443  Methanobrevibacter sp. AbM4
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