Conserved Protein Domain Family
BPD_transp_2

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pfam02653: BPD_transp_2 
Branched-chain amino acid transport system / permease component
This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.
Statistics
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PSSM-Id: 396977
Aligned: 29 rows
Threshold Bit Score: 96.173
Threshold Setting Gi: 121727915
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P73350   7 GIFNGLSTSSVLLIAALGLAIVFgLMGVINLAHGELMMLG-AYSTFVVQNLFQSLgdpw--fdlyIFAALPVAFLVAAIA 83  Synechocystis sp. PCC...
Q9I6Z5  59 GLGELLVKAMPILLCALGLALAY-QARVWNIGAEGQLLVGaLAGSAVAIQLLDWQsr------waLAWVLLAGTAAGALW 131 Pseudomonas aeruginosa
Q9HR22  99 RVASLLRSTTLLVFTGLAVAVSF-RAGMFNIGVQGQLLLGaLAAALATVYAAPLVpggvvgtlvlVPVGIVAGALAGGVW 177 Halobacterium salinarum
Q98PV1  73 NT--FLLMVVVFIIASLGIALTF-KAGVFNIGISGQMMMG-GSVGMYLIYSQGQInh------gnVFGAFIISILLGGLW 142 Mycoplasma pulmonis
P75515  73 NIENFARQIAIYTLAALAFSFCM-SVGVFNIGISGQMMAGaNFGFMMILKVFPESfrpa---fggQIITILLMILGSVTV 148 Mycoplasma pneumoniae...
Q9PRD1  65 SPDIYLTKVAILGIAALSFIFAF-KAGLFNIGISGQMLGSgLIMLLVVKNMQIANinmp--nvlgQFFLLIIAMLAGAMF 141 Ureaplasma parvum
Q9YG34   1 MISAVLTTLIPLSLAALGEAVLE-RTGRVNLGVDGLMAVG-AAVGALAGVETGS-----------LLAGLAAGALAGGVG 67  Aeropyrum pernix
O83343   7 MVALTLVFSTPILITALGGLFSE-RSGVINIALEGLMMFG-AFSTATVTVLCEPYti------aaPWIALGVGMAVAASV 78  Treponema pallidum
O30015   8 IAVFGAVVGGIWGLVASGFSLIFgVSRILNFAHGAAFVSS-AFLAYALISEGYN-----------LYLAILAGLLLSALI 75  Archaeoglobus fulgidus
P0AEX7  11 QMFNGVTLGSTYALIAIGYTMVYgIIGMINFAHGEVYMIG-SYVSFMIIAALMMMgi------dtGWLLVAAGFVGAIVI 83  Escherichia coli K-12
P73350  84 GLVLERQVIRYLYGRP---------LETLLatwgvslilqqfvrsvnwIMVLVVGIFLLLYFGGTWLIKRQA-----GGK 149 Synechocystis sp. PCC...
Q9I6Z5 132 AGFAAWLRTRFNANEI---------LTTIM------------------LNYIALNLLLYGVHGPLKDPDGFN-----FPQ 179 Pseudomonas aeruginosa
Q9HR22 178 GAIPGALKAYADANEV---------ITTIM------------------LNFVAANLAYVAVSTWFTPADSSL-----VQT 225 Halobacterium salinarum
Q98PV1 143 ALIAGIAKSFFKVHEV---------VSTIL------------------LNWIATYVIKQIYEGTSFINRQNP-----EST 190 Mycoplasma pulmonis
P75515 149 AMVVAALKVFFKVNEV---------VSAIM------------------LNWVIVLVSAYLVGTYIKPEKTDT-----SQF 196 Mycoplasma pneumoniae...
Q9PRD1 142 AVFIGILKVFLKINEV---------VSSIL------------------LNWIMFYITRYVVFTAQSKMYNPT-----PDQ 189 Ureaplasma parvum
Q9YG34  68 SLSYIILTDRLGVNMI---------VAGLL------------------VFFAGIGLGD------LVGSKIAG-----RPG 109 Aeropyrum pernix
O83343  79 ALFYAYLSVRLCSDQI---------IAGTA------------------INLCATGMTVFFAQVIFGQQGTQA-----YSR 126 Treponema pallidum
O30015  76 GLAVYALTKPVRDREV---------MVIILt-----------------LAFALLVQQVLLVLYGDRGVSIEP-----FVS 124 Archaeoglobus fulgidus
P0AEX7  84 ASAYGWSIERVAYRPVrnskrlialISAIG------------------MSIFLQNYVS--LTEGSRDVALPSlfngqWVV 143 Escherichia coli K-12
P73350 150 PWLGKAQVILFFLSAAISgisgfvvaqansplwnrawfgarnvnvsaptwlrgglaigtfqvpytrifiiFLTLLCLLAV 229 Synechocystis sp. PCC...
Q9I6Z5 180 SALFGEASRLPALFEDSRvhl-----------------------------------------------gaLFGLLALAAV 212 Pseudomonas aeruginosa
Q9HR22 226 ATIPAAARIPNVPFGFQPrdnfs-------------------------------------------llglLFAVALVVGV 262 Halobacterium salinarum
Q98PV1 191 IRFDTTSLNIENAAQFRNffqsnt----------------------------------------liysmlALAIFLAIIF 230 Mycoplasma pulmonis
P75515 197 YSIELPDAFALYNFSDVQqkygw-------------------------------------------ltslVIAIAAAIFI 233 Mycoplasma pneumoniae...
Q9PRD1 190 VGSRSIPFADNYSLFHLAsgygy-------------------------------------------lfalLIFISLSIII 226 Ureaplasma parvum
Q9YG34 110 PVLTSLYTTAATIG------------------------------------------------------------IAAVAL 129 Aeropyrum pernix
O83343 127 GLVKTSYGFFSRIPVLGPmvfth------------------------------------------typtvYLGFVLVALA 164 Treponema pallidum
O30015 125 GFAEIGGVKVTYMRILSF----------------------------------------------------VLAVLCLTAL 152 Archaeoglobus fulgidus
P0AEX7 144 GHSENFSASITTMQAVIW----------------------------------------------------IVTFLAMLAL 171 Escherichia coli K-12
P73350 230 YLIFYRSNWGLRIRAVTQNRGMSACLGIPTGQVDALTFALGSGLAGIAGCAISFLGAVGP-------NIGQN----YIIN 298 Synechocystis sp. PCC...
Q9I6Z5 213 WVLAQRSFLGFQVRVLGLDRRAAGFVGFREKRLVWFVLLFSGALAGLAGVCEVAGPIGQLv-----pQVSPG----YGYA 283 Pseudomonas aeruginosa
Q9HR22 263 AYLLARTSFGYDLRTSGSQPEAAAYGGVKEKRTMVTSMGISGALGGISGAMLVLMVQGRWl------SNLPQ----LGFD 332 Halobacterium salinarum
Q98PV1 231 WIIFSKTTIGYKIKMIGLNPNASDYSGTNKNVLNMSVFFVSGMFAGLAGIIMFLMRDRFVpv----nSFPLP----AGFD 302 Mycoplasma pulmonis
P75515 234 AVLMKFTVFGHKLKSTGLSVTGSQAAGYSVKKYQFLSFVISGILSGLLAAVVYTASFEKQltfsdvgDFGITsvpiTGFD 313 Mycoplasma pneumoniae...
Q9PRD1 227 WVILKYTVFGHKVLSVGKSFDAAKYAGYRTKIISLATFAISGALAGALAMVNYTSTTTNAivisqaaDALPT----QGYD 302 Ureaplasma parvum
Q9YG34 130 HLILYNTVTGTALRVVGENPAAAKERGVPVWRLRLSAALVQGLSAGLAGYIMVAGLSYGKwy----sGVTAG----LGWV 201 Aeropyrum pernix
O83343 165 WYVLYRTPFGVHVRATGDQPYAVDGAGLSVFRLRSAAVVISGLCAGLGGGVLILT------------QDIQY----TVYS 228 Treponema pallidum
O30015 153 EVFVTRTKLGKKVIATAQDSRAAMMVGIDIEKIFLLVMVLSSVLAGFAGILYAQIFAVSP-------EVSLR----ALIY 221 Archaeoglobus fulgidus
P0AEX7 172 TIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAVAGVLLGQFYGVINp------YIGFM----AGMK 241 Escherichia coli K-12
P73350 299 TFMVVVVGGVg------NLLGTIIASLAIGVSSDlIGSGTLIrlfppegalqPlyefftffatTSMARVLVFALIILFL 371 Synechocystis sp. PCC ...
Q9I6Z5 284 AITVAFLGRL-------NPFGILCASLLMALLYL-GGEAAQMsl------nlP----------LALSGLFQGMMLFFLL 338 Pseudomonas aeruginosa
Q9HR22 333 GITVSILAGN-------NPLGVGFAALLFGVLKS-GSAAIGFgt------nvP----------PALVDVLRGLIILFVA 387 Halobacterium salinarum
Q98PV1 303 TIVISLIAYN-------SPIGIVFSSLFYALFDT-GLNKIPSf---------P----------REFYLIFIGVMMFIIS 354 Mycoplasma pulmonis
P75515 314 GIAIGLIALN-------SPARIVIVSTIISFVTIgAKPAGLN---------------------AATASLVLGIMMYFAA 364 Mycoplasma pneumoniae ...
Q9PRD1 303 GIAMGLISLA-------HPLATIPVSFLMGLLQQsADNLGGSf-------------------pQDLSGIIISFVMLGAA 355 Ureaplasma parvum
Q9YG34 202 ALGIVILGYW-------TPIGVLIASTAVSTVFS-MRTQIAAat------giP-----------PLADAIPY---ILVL 252 Aeropyrum pernix
O83343 229 THGTGFIALAalisgrwHPFGVLVTSVLFGFSQIlNVYATSVell----khlP----------IELFSALPYALTVVVL 293 Treponema pallidum
O30015 222 AFAIVILGGLg------SLRGSVVASFIVGYILVtTITFLGA----------------------RWSEFVMLLTIVAIL 272 Archaeoglobus fulgidus
P0AEX7 242 AFTAAVLGGIg------SIPGAMIGGLILGIAEAlSSAYL------------S----------TEYKDVVSFALLILVL 292 Escherichia coli K-12
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