2PW9


Conserved Protein Domain Family
FdhD-NarQ
?
pfam02634: FdhD-NarQ (This model is not part of the current CDD release)
FdhD/NarQ family
A pan-bacterial lineage of proteins. Nitrate assimilation protein, NarQ, and FdhD are required for formate dehydrogenase activity. Structurally, they possess a deaminase fold with a characteristic binding pocket, suggesting that they might bind a nucleotide or related molecule allosterically to regulate the formate dehydrogenase catalytic subunit.
Links
?
Statistics
?
PSSM-Id: 515073
Aligned: 103 rows
Threshold Bit Score: 184.682
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
2PW9_A         32 AIETPYAIALNDr----VIGSSMVLPVDLEEFGAGFLFGQGYIK-KAEEI--REILVC---------------------- 82  Desulfotalea p...
WP_015480713   24 VVEAPLQININNe----PYTVVMRTPDDDFELIRGLLFAEDIYKqKAPLA--MNILKQ---------------------- 75  Polaribacter s...
ABS04803       31 AVEEPLQLEVDGe----QLTVTMRTPGDDVDLALGFLHAEGLLT-AAEDV--VSAVHCtd-------------------- 83 
Q5Z057         27 AVEEPLEIRIGGq----SLTVTMRTPGSDIDLVHGFLLSENMIG-AAEDV--VSARYCag-------------------- 79  Nocardia farci...
Q0RN01         18 VGEEPLEIRVGGr----ALAVTMRTPGDDMDLALGFLLGEGMIA-GAADV--ASMRYCvgrseasgrseasgrgeasgrg 90  Frankia alni A...
WP_012097859   40 ALEEPLEIRIAGe----TVGVLMRTPGDDHRLALGYLFSEGIVS-SASEF--SAVYHC---------------------- 90  Anaeromyxobact...
Q53WG5         25 AAEAPLEIRLRYrdevaSLGVVLRTPGQDAELAAGLLYTEGLLQ-DPKEV--LAIAPC---------------------- 79  Thermus thermo...
WP_011696910   24 AVEELLEIYVDDs----PYAITMRLPGDDINLAAGFCFTEGIIR-SYDDI--ASIEHC---------------------- 74  Syntrophobacte...
Q30VI7         24 IIEAPMEIVVNGv----PWAALMRTPGDDEALALGYCHTEGLLQ-QGEPYsmNRCTAA---------------------- 76  Desulfovibrio ...
jgi:Dole_1537  17 IVEEPLSIRIEGa----SYAVVMRTPGEEKEHVAGFCLAEGLVE-GPGDI--VTIGFC---------------------- 67 

2PW9_A         83 ---------------PQ---GriS---------VYADV------ENE--E-PRevIITSGCggtgkipkem--------- 117 Desulfotalea p...
WP_015480713   76 ---------------ED---Ni-P---------KIVDVsiskdhLGKgyLnKRtlLSVSSCgicgkkelnd--------- 118 Polaribacter s...
ABS04803       84 --------------lGP------DgeptynllrIAARPgsr-laGER--V-ARpfTTTSACgvcgsasvedv-------l 132
Q5Z057         80 --------------tDE------QgrntynvldVELRRpvp--------vrTRhvLTTGACglcgktaldev-------r 124 Nocardia farci...
Q0RN01         91 easgkgeaaggdgavDA------DgrptynvldVALAPgva-ppEVD--V-TRnfYTTSSCglcgkasidav-------r 153 Frankia alni A...
WP_012097859   91 ---------------GR---P--GeeaygsaieLAPASgar-idWERieGtRRasASSSACgvcgrravedl-------- 141 Anaeromyxobact...
Q53WG5         80 ---------------AD---G--SlppearegvIQVFLrh--plPPPp---RRhlALTAACgacgrealpd--------- 125 Thermus thermo...
WP_011696910   75 ---------------EAipgEr-R---------VMVHLsrdrkrAKSvrKeRAeyLSKSSCglcgkreaeei-------- 121 Syntrophobacte...
Q30VI7         77 ---------------DG---Tm-R---------MLLEIqggprrVQEmmRgRGv-RMGFSCcgnrnavsaqelvrtlppv 127 Desulfovibrio ...
jgi:Dole_1537  68 ---------------TE---Ag-Tnv-----atVTLTdtr-rqqVAEllErKGf-VSQTSCgicgkavvddi-------- 113

2PW9_A        118 -legefaplaDYCLPFAEIKSFIREALHSSPLGPQTHCVHGCGLWN-NGR--LQVYHEDVGRHNAVDKVLGSILL-GRA- 191 Desulfotalea p...
WP_015480713  119 ikvtgnnlenRYQLTANQLHKMYEVMHTLQKTYNKSGGSHAAALYSkDNN--LLTLKEDIGRHNAVDKAIGNLLInENL- 195 Polaribacter s...
ABS04803      133 arvpaplhadPVRVGTDVLAGLPDTLRAAQSAFERTGGLHAAGLFDaTGA--LRCLREDVGRHNAVDKVVGWGLReGLLp 210
Q5Z057        125 avtrfplpahGVTLAADVLADLPATLRAGQSVFQATGGLHAAGLFTvDGT--PLAVREDIGRHNAVDKVIGWALReNRVp 202 Nocardia farci...
Q0RN01        154 lrsrftvaddPLLLDAATVTGLPDALRAGQRLFATTGGLHAAALAGvDGV--LRAVREDVGRHNAVDKVIGAAVRdGLVp 231 Frankia alni A...
WP_012097859  142 -vaglvppepiAPVPAALLAEKVEALRDHQPVFAATGGAHVAALWAqDGS--LVAAHEDVGRHNAVDKVVGALLLaRAEa 218 Anaeromyxobact...
Q53WG5        126 pgrlglspppPLAVDPDLLLALPERLGEAQRLFRATGGLHAAALFDrEGR--LVALREDVGRHNALDKLIGWAFLqGKLp 203 Thermus thermo...
WP_011696910  122 -fddippvetcRHIELEEILRLKDVFEGRQAIFPRTGSTHSAAAFDdRAN--LLAFAEDIGRHNAFDKVIGALLKtREL- 197 Syntrophobacte...
Q30VI7        128 pssgpadnkeAFRVAPETLNALLREAEGYQALFSRTGGTHFCALY--DGQltMLAFAEDTGRHNALDKAAGQALMqGTA- 204 Desulfovibrio ...
jgi:Dole_1537 114 -rqvvvpiavtARFPAARLMALVDDLPRRQSLNRETRGAHAAMILDaREA--LLSLAEDVGRHNALDKAIGRVMMeGRL- 189

2PW9_A        192 ------SNNSAVYTTGRLTSDMVLKCARIGIPIIMSRTSPSSLGLALAKRSGATLVAYSRPERINVFNAPERIL 259 Desulfotalea psychro...
WP_015480713  196 ------KKAHYLLVSGRVSYEIVTKAFIAKIPVIVAVSACSSLAVDFAKEFGICLIGFTRENKLTIYSNTNAIN 263 Polaribacter sp. MED152
ABS04803      211 ------LRGSVLVVSGRASFELVQKAAMAGVPVLAAVSAPSSLAVSLAREVGMTLLGFVRPPRANAYSREDRLV 278
Q5Z057        203 ------AHELVLIVSGRASFELVQKAVMAGIPILGAVSAPSSLAVDLAEEAGLTLVGFLRGETMNVYSGAHRLR 270 Nocardia farcinica I...
Q0RN01        232 ------LSGHALVVSGRASFELVQKAWMAGVPMLVAVSAPSTLAVDLAEEAGMTLAGFVRGDSMNIYTGAHRVA 299 Frankia alni ACN14a
WP_012097859  219 aagapeLRPALLTVSSRAGFEIVQKAARARVPIVATVSAPTSLAVELARAAGLTLAGFVRPGRMNVYAGAERLI 292 Anaeromyxobacter sp....
Q53WG5        204 ------LHDHILLVSGRAGYELLVKAVAAGIPVFCAVSAPTSLAVALAQAYGLTLVGFLRPGRMNVYAGRERVg 271 Thermus thermophilus...
WP_011696910  198 ------GKVFLGVVSSRLSFEMVQKAGVAGFEVFAGLSAATSLAVAMADRLNMTLIGFLREKSMSIYTHPERVL 265 Syntrophobacter fuma...
Q30VI7        205 ------ADVHLVLLSSRLSFEMVQKSLALKARVVAGLSAVTSMGTELAEASGITLVGFLRSGRMNIYTHAQRMV 272 Desulfovibrio alaske...
jgi:Dole_1537 190 ------SDAALGIVSSRLSYEMVQKAARAGLQVLVGLSRPTALAVDLARSVGITLVCVQSG-RLMVFGEASRVF 256
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap