Conserved Protein Domain Family
LUD_dom
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pfam02589: LUD_dom 
LUD domain
This entry represents a domain found in lactate utilization proteins B (LutB) and C (LutC), as well as several uncharacterized proteins. LutB and LutC are encoded by th conserved LutABC operon in bacteria. They are involved in lactate utilization and is implicated in the oxidative conversion of L-lactate into pyruvate
Links
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Statistics
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PSSM-Id: 396925
Aligned: 125 rows
Threshold Bit Score: 91.5174
Threshold Setting Gi: 158111984
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_011322585       64 IEEVRAAVEANGGEVYVADDAADANDYIETVLEMRDAdrivksksmtteelslnerlaagGFEVTETDL-GEFVIqvade 142 Natronomon...
jgi:Gura_4126      16 CEKAVESLGKNGFTAVYCPTGQEAYDYIVKEAADAAS-----------------------VGFGGSMSV-ADLKV----- 66  Geobacter ...
BAF60825           16 CKRAVEALNRNEFTAIYCSTRQEASDYIIKEAAEAQT-----------------------IGFGGSMSV-AGLKV----- 66  Pelotomacu...
WP_011721711       13 GEKVVKALKENYFDAIYFEKREDAAKYILDNVKDGDS-----------------------VGFGGSVTI-QQLGV----- 63  Clostridiu...
jgi:Dred_0911      12 GEKVVQALKKNQFNAVYFPNKEEAEKYILDFISPGAQ-----------------------VGFGGSMTLtEGMGL----- 63  Desulfotom...
Q6M046             13 GKKLVENLKKNLFDAYYFEDGSEVSKYIMNYVGTGTK-----------------------IGFGGSVTV-QSLNI----- 63  Methanococ...
jgi:Franean1_4815  21 IDRATAALRENGYLVHVVDTAAQARELVAGLLPTDQS-----------------------VFTASSETL-RLAGIt---- 72  Frankia sp...
Q5V6G7             27 IEETVENLEANGFEVIVVNSADDALAELQSLIPAEAS-----------------------VMNGHSTTL-EEIGF----- 77  Haloarcula...
Q9BI24             30 LMETVKNLEAKNHRVSVVENEADALNLLLNEIPKGSE-----------------------VMCASSCTI-DEIGF----- 80  Dictyostel...
Q8T2H5             31 LNETIKSLESKNHKVLLVDNEETALEEIKKMIPDKST-----------------------VMGAGSVTL-DEIGF----- 81  Dictyostel...

WP_011322585      143 spshliGPAMHRSADDIAALFNDRLdpaeplagdphelTAFARDVVGEHIRAADAGITGANfVVSETGTLCLVTNEGNA- 221 Natronomon...
jgi:Gura_4126      67 ------ADRLKEEGKEILNHSLPGL-------------SLEERVAVMRRQLTCDLFLTGTN-AVTLSGFLVNIDATGNRv 126 Geobacter ...
BAF60825           67 ------DEVLKGMGKELLIHGAPGL-------------SPEERLAVRRRQLTSDLFLTGTN-ALTLSGCLVNIDATGNRv 126 Pelotomacu...
WP_011721711       64 ------KEKIKEMNTTILDHGDPNL-------------TAEEKLDVKRAQLTSDLFLCSSN-AITMNGELVNIDGAGNRv 123 Clostridiu...
jgi:Dred_0911      64 ---------VEKVKMKGAEALVHGTpq----------lSAEEKLEIMRKQQICDVFLASTN-AVTLDGFLVNIDGVGNRv 123 Desulfotom...
Q6M046             64 ------AEQAMEKGAVILDHNDASL-------------TQEEKMDIMRQQLTSDIFISSTN-AITASGELVNIDGVGNRv 123 Methanococ...
jgi:Franean1_4815  73 ------ADIDESGKYNSVRAAAPPP--------------SEDVYATIRLGATPDV-VVGSVhAITENGHLVVGSASGSQf 131 Frankia sp...
Q5V6G7             78 ------DEYLSDGDHGWESLPEEIWsi----------dDDAKRQAARRESQTADYFLGGIN-GISQTGELVAADRSGSRi 140 Haloarcula...
Q9BI24             81 ------KKIYFSDDSPFVNVHKKILa-----------lPADKQADARKDALTSQYFLSSVT-AISKTGNVYVADASGTR- 141 Dictyostel...
Q8T2H5             82 ------KSYYFSDNHKWDNLHKKIFae----------tDSGKQIILRKHALACDYFLSSVG-AISKQGDLFVADASGTR- 143 Dictyostel...

WP_011322585      222 RKTAVTPPTHVAVAGVEKLV-PSVSDLQPFVEL--IARTGTG-QDITSYLSLVtp-----pVETPAVDFETDEYVPaDDR 292 Natronomon...
jgi:Gura_4126     127 GSMFFGPKKVIVVAGRNKLVdGDVGAAVKRIKDcaTPPNARRlNYNTPCSKTGfcsdcnspDRICRITTII-DRKP-RLT 204 Geobacter ...
BAF60825          127 GSMMFGPKKVIVVAGRNKLV-SSVDEAIRRIKEyaAPPNARRlDYNTPCAQTGfcsdcrspQRICRIITIL-EKRP-ALT 203 Pelotomacu...
WP_011721711      124 AAMTFGPKKVIVVAGINKIA-TDESSAFERIKVlaAPKNTKRlSKSTPCTKTGvcmnckneDRICRIYSVI-KRKP-MGA 200 Clostridiu...
jgi:Dred_0911     124 AAMTFGPKKVIIVIGTNKIC-KDVDAAFNRLETivAPKNNKRlNYENPCTVNGscvncqtsTRVCRIYSVM-KRKP-MLS 200 Desulfotom...
Q6M046            124 SAIVFGPKKVIIVVGLNKLC-KDVETAFERIKMqaAPKNMKRlGFLNPCIKTGycvncdaeTRACRIYSVI-KRRP-MLT 200 Methanococ...
jgi:Franean1_4815 132 APYASGARRAIWVVGAQKVV-GDLETALRRIRTysLPREHQRlADLYGQSSFI--------GRILILEREA------FPE 196 Frankia sp...
Q5V6G7            141 GAYPFAASNVVIVSGVNKIV-PTLEDALDRLETvaYPLENERaKEAYGVDSAI--------AKQLILRQELEEG------ 205 Haloarcula...
Q9BI24            142 VGGFTAAKNLIIVSGYNKIV-DSDELAVQRTEQfcLPCESVR-------ARWAyk----vpGSMIQNLLGMKHG---APN 206 Dictyostel...
Q8T2H5            144 VGGFTAANNLIVVAGLNKIV-ESESDGVKRATG--FCYQCESvRARKAYPGVA--------GSIVQNFAQIKFGNAmGPK 212 Dictyostel...

WP_011322585      293 -TFHLVLL 299 Natronomonas pharaonis
jgi:Gura_4126     205 -DVRVLVV 211 Geobacter uraniireducens Rf4
BAF60825          204 -DMRVLVV 210 Pelotomaculum thermopropionicum SI
WP_011721711      201 -NMTVIIV 207 Clostridium novyi
jgi:Dred_0911     201 -DMTVVVI 207 Desulfotomaculum reducens MI-1
Q6M046            201 -DMTVLVV 207 Methanococcus maripaludis
jgi:Franean1_4815 197 -RGTIILV 203 Frankia sp. EAN1pec
Q5V6G7            206 -RTTVVLI 212 Haloarcula marismortui
Q9BI24            207 -KHHIILI 213 Dictyostelium discoideum
Q8T2H5            213 rNTTIILI 220 Dictyostelium discoideum
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