1QYA,1YM5


Conserved Protein Domain Family
PhzC-PhzF

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pfam02567: PhzC-PhzF 
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Phenazine biosynthesis-like protein
PhzC/PhzF is involved in dimerization of two 2,3-dihydro-3-oxo-anthranilic acid molecules to create PCA by P. fluorescens. This family also contains uncharacterized Mycobacterial proteins, though there is no significant sequence similarity to pfam00303 members. This family appears to be distantly related to pfam01678, including containing a weak internal duplication. However members of this family do not contain the conserved cysteines that are hypothesized to be active site residues (Bateman A pers obs).
Statistics
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PSSM-Id: 396907
Aligned: 11 rows
Threshold Bit Score: 275.403
Threshold Setting Gi: 81550217
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1QYA_B     18 VDAFTSQPFRGNSAGVVFPAD-----NLSEAQMQLIARELGHSETAFLLHSd---------dSDVRIRYFTPTVEVPICG 83  Escherichia coli
Q9RUQ2     21 VAAFTTVPGQGNRAGVVLDAG-----ELTGEQMQRLAAFLEAPETVFVTRLs---------dGLGRVRYFTPTQEVDFCG 86  Deinococcus radiod...
Q9RJQ0     11 YSAFTDDPAGGNPAGVVLDAS-----GLDDPAMLAIAAEVGYSETAFVTGGda-------erRRFRVRYFSPLAEVAFCG 78  Streptomyces coeli...
O31570      9 YEAFTSSPGKGNPAGVVLQGD-----DYTEDEMQIIAERAGYSETSFIRKse---------sADLELRYFTPGHEMNLCG 74  Bacillus subtilis ...
P73125      8 LDVFTDQLFGGNPLAVFPDAE-----GLTDGQMQKIAAEINYSETVFVLPPvt-------etGNFRLRIFTPKRELDFAG 75  Synechocystis sp. ...
Q9SDD7     11 VDAFAAEPFKGNPAAVCLLEGedaaaAADERWMQSVAAEFNLSETAFLIRDpsssaaaadaaPRFRLRWFTPVAEVNLCG 90  Japanese rice
Q66GM9     14 VDAFTESAFKGNQAAVCFLEEd---hERDDVWLQSMASEFDLPLTCFLIPIpgs------epPRFLLRWFTAVAEMDICG 84  thale cress
Q9ZVS2     12 VDAFAESAFKGNPAAVCFLEDd---nERDDAWLQSLATEFNISETCFLTPIig-------dlPRFRLRWFTPVAEVDLCG 81  thale cress
NP_192195  31 VDAFTDSAFKGNPAAVCFLNDd---nERDDTWLQSLAAEFNISETCFLIPItg-------fqARFSLRWFTPLAEVDLCG 100 thale cress
O69754      7 IDAFASEPLQGNPVAVFFDCD-----DLSGERMQRMAREMNLSESTFVLRPqq--------dGDARIRIFTPVNELPFAG 73  Pseudomonas aerugi...
1YM5_A     10 VDVFTEKPFMGNPVAVINFLEid-enEVSQEELQAIANWTNLSETTFLFKPsd-------kkYDYKLRIFTPRSELPFAG 81  baker's yeast
1QYA_B     84 HATVAAHYVRAKVLGL-----GNCTIWQTSLAGKHRVt----------IEKHNDDYRISLEQGTPGFEPPLEGETRAAII 148 Escherichia coli
Q9RUQ2     87 HATVALGRVLAQAGRW-----RGEALELETLAGRIPLr----------LVLDAGGGECRVWMHQPAFGTRAVGRGWHREL 151 Deinococcus radiod...
Q9RJQ0     79 HATVALAVALAERLG-------PGEVVLDTPAGEIPVs----------TAVDGTGAVRATLTSVPTRSRPALPAERDAAL 141 Streptomyces coeli...
O31570     75 HATVASLYALCEKGMLe----SGKTYSIQTKAGILPVk----------ISEKDGRIHITLEQASPQFKPFTGDRKKLADA 140 Bacillus subtilis ...
P73125     76 HPTIGTTYLLGLLQPPsp--lVTTTWQLEEPVGLVPVtl--------hYKQGQLVQTELTVAQLPQTKDSAPSCEDLALL 145 Synechocystis sp. ...
Q9SDD7     91 HATLASAHFLFTTVLAkqqhaAAAMVEFVTRSGILTAkkvpappppanDGGVPGEEKLFIELDFPMIDLVEYDSAETLSI 170 Japanese rice
Q66GM9     85 HATLASAHSIFSNSLVg----SSDTVEFSTNSGILTAk---------rLSDCDSKRSFLIEMNFPVITTCEYSSKDVSIF 151 thale cress
Q9ZVS2     82 HATLASAHVLFSTGLV-----GSETVEFDTLSGILTAk---------hLKNDDDGEESSIELDFPVVPTYEVNYIDDDLS 147 thale cress
NP_192195 101 HATLASAHCLFSNGLV-----DSDMVEFVTRSGILTAkrvsd--tselSDGEVKGGTFLIELNFPVVTTCDVNLSDVSSS 173 thale cress
O69754     74 HPLLGTAIALGAET-------DKDRLFLETRMGTVPf-----------ALERQDGKVVACSMQQPIPTWEHFSRPAELLA 135 Pseudomonas aerugi...
1YM5_A     82 HPTIGSCKAFLEFTKNt----TATSLVQECKIGAVPI----------------TINEGLISFKAPMADYESISSEMIADY 141 baker's yeast
1QYA_B    149 NALHLTEDd-----------iLPGLPIQVATTGHSKVMIPLKPEVDIDALSPDLna----lTAISKKIGCNGFFPFQIRP 213 Escherichia coli
Q9RUQ2    152 AEALGLSDrl----------lHRGLPLAAASTGLWSVFLPLLDASLLEGLEPDL-------PRIAELSRELGVVSVYAYA 214 Deinococcus radiod...
Q9RJQ0    142 GALGWTAAd-----------lDPALPAHVAFGGNDHLVLAAASRARLADLDYDF-------DALAEVMRRYGWTTVDLVW 203 Streptomyces coeli...
O31570    141 LGITDEDF-------------HEDLPIVFGSTGIWTAIVPLKSLEASKKMVPDNkq----fPEVLVDLPKASVHPFTFET 203 Bacillus subtilis ...
P73125    146 LGLSIDQLq------------QGEYEPQAYSCGLPFLFIPLINEEALNRISFNPsvwqnllAGQWADCVYCLAPGDPSLG 213 Synechocystis sp. ...
Q9SDD7    171 PETLNGA----------------RVVSVWKSSTAGDLIVELSSGKEVADIIPNI--------NEIKKCDGRGVIVTGPAP 226 Japanese rice
Q66GM9    152 SKALNGATivdvretktdrliFKPLIGAFKTTSTDQIIVVLSSWESVIEFQPRV--------DDIVKCPGKVMIVTAAAP 223 thale cress
Q9ZVS2    148 LFSKALN---------------GATILDVKAT-KKDLLVVLSSWEAVIDLKPRL--------DEISKCPCEGMMVTAAAS 203 thale cress
NP_192195 174 MITKALN---------------GATIVDIKATATNNILVVLPSKESVTELQPRM--------DDILKCPCDGIIVTAAGS 230 thale cress
O69754    136 ALGLKGS----------------TFPIEVYRNGPRHVFVGLESVAALSALHPDH--------RALCDFPDLAV----NCF 187 Pseudomonas aerugi...
1YM5_A    142 EKAIGLK--------------F-IKPPALLHTGPEWIVALVEDAETCFNANPNFam---laHQTKQNDHVGIILAGPKKE 203 baker's yeast
1QYA_B    214 GKNETD--GRMFS-PAIGIVEDPVTGNANGPMGAWLVHHNVLphdGNVLRVKGHQGRALGRDGMIEVTVtirdnqpEKVT 290 Escherichia coli
Q9RUQ2    215 PVGVNRfaARDFA-PLVGIPEDPVTGSAGGALLALLASEGRLplrGNRASGLIYQGHALGTPGEIEVEVevrgtrvEAVQ 293 Deinococcus radiod...
Q9RJQ0    204 RESAGLyhARNPF-PVGGVVEDPATGAAAAAFGGYLRELGLV---TGPATIAVRQGEDMGRTSELLievg---prdPRTR 276 Streptomyces coeli...
O31570    204 VHPDSDlhGRHFSsPYSGTIEDPVTGTASGVMGAYMKHYGNA----EQHKFIIEQGQEIGKDGKVEIEMneag-ghvKVN 278 Bacillus subtilis ...
P73125    214 LSDNKLihGRMFA-PGLGIAEDPATGSGVAALGGYLDDRLDT---PGSHHWQIEQGKALGRPSQLQLTVvkdgqgiRAVK 289 Synechocystis sp. ...
Q9SDD7    227 AGSDYDffSRFFC-PKFGIDEDPVCGSAHCVLAPYWGGKLGK--------QKLTAFQASPRSGTLYLELdge---nrRVR 294 Japanese rice
Q66GM9    224 QGSPFDfcSRLFA-PKLGLNEDSVCGSAHCSLAHYWSLKMNK--------CDFVAFAASQRSGTLKvhyd---kekQRVL 291 thale cress
Q9ZVS2    204 DGSTYDfcSRYFA-PRFGINEDPVTGSAHCALAHYWSLRMNK--------CDFFAYQASSRGGTLKvhld---kekQRVL 271 thale cress
NP_192195 231 TGSSYDfySRYFA-PKFGVDEDPVCGSAHCALAHYWSIKMNK--------FDFLAYQASSRSGTIRihld---kekQRVL 298 thale cress
O69754    188 AGAGRHwrSRMFS-PAYGVVEDAATGSAAGPLAIHLARHRQI---PYGQQIEILQGVEIGRPSRMYARAegagervSAVE 263 Pseudomonas aerugi...
1YM5_A    204 AAIKNSyeMRAFA-PVINVYEDPVCGSGSVALARYLQEVYKF---EKTTDITISEGGRLKRNGLMLASIkkeadnsTSYY 279 baker's yeast
1QYA_B    291 ISGTAVILFHA 301 Escherichia coli
Q9RUQ2    294 VGGCAAVEREG 304 Deinococcus radiodurans R1
Q9RJQ0    277 VTGQAVPV-SG 286 Streptomyces coelicolor
O31570    279 MTGTAVYSETR 289 Bacillus subtilis subsp. subtilis str. 168
P73125    290 VAGRSVLVSEG 300 Synechocystis sp. PCC 6803 substr. Kazusa
Q9SDD7    295 IQGEAVTVMAG 305 Japanese rice
Q66GM9    292 LTGKAVTVMKG 302 thale cress
Q9ZVS2    272 LRGKAVTVMEG 282 thale cress
NP_192195 299 LRGKAVTVMEG 309 thale cress
O69754    264 VSGNGAAFAEG 274 Pseudomonas aeruginosa PAO1
1YM5_A    280 IAGHATTVIDG 290 baker's yeast
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