Conserved Protein Domain Family
SPAN
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pfam02510: SPAN (This model is not part of the current CDD release)
Surface presentation of antigen domain
Surface presentation of antigens protein (SPAN), also know as invasion protein invJ, is a Salmonella secretory pathway protein involved in presentation of determinants required for mammalian host cell invasion. This entry represents a C-terminal domain found in these proteins. This domain is composed of a 4-stranded beta sheet followed by an alpha helix.
Links
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Statistics
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PSSM-Id: 514976
Aligned: 33 rows
Threshold Bit Score: 57.0193
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_094564569 259 GVTQDGWVYQFRSWGTQHAVRVSQTPGMNSASSssfaalALHPTSALVEQRLNAHGDTTGrSDQWLL--QEHGEEGRQQQ 336 Herbaspirillum ...
1_pfamImport   1 AVPAPGMRYAFQQWGDGHFVQIRAAEIDGQPGF------VLGASDPTVQRRLSAMWSAASdAGACVA--GSGVAVHAIEP 72 
WP_150696178 236 QGKGRDMHYPLSSWGTGHFVRVEFQGTGAGAGF------VLHPSSDAVQQRMQMHWQAAA-GEPWQL--AHEHSGNPQQR 306 Pandoraea terrae
WP_234054928 348 GQLQRGLNYKFTSWNDGSSVRVELAKAQEI---------HATTSSDTVQQVLNDSQHLLEtERTLVIdeHRDDEERKQRY 418 Yersinia ruckeri
Q8X6E8       102 NVRENELTYQFQRWGQNHTVRILESSEGI----------RLKPSDTLVSDRLHEAQHNDVtAQRWVL--TEQDERQGQRH 169 Escherichia col...
WP_108439726 399 VLKGSEMTFRFSKWGDGHTVKVQTKSSGYASQL------TLQPSDALVAHRLSEHLSISApPDHWTL--LKDDEEHGHRQ 470 Glaciimonas sp....
WP_026822623 262 SLPEAELRYTFTQWQGTHHVDIYRITNHHL---------QLMASNSHVMSILQRHLNERAsPSAVSL-----FDTLNITL 327 son-killer infe...
WP_290607903 164 PSPEAELRYTFTQWQGTHHVDIYRIADHNL---------QLMASNNYVMSILQRHLNEKVsARSVFL-----SDTLNITL 229 Arsenophonus sp...
WP_189535728 234 VQPDGSLTYTFKSWEGNRFVTVRDIRGDADAARw-----RLEPSDAMVGQRLASQMPHTV-AGEWQLgdGNSGGHARHDQ 307 Paludibacterium...
WP_024486137 243 PIGSGKLTYNFGRWGEGHQVDVTLLNQEQDTHF------QFEPSDSLVEQRMTEQWEQTDiPPYWSL--LEDAGGEHQGH 314 Serratia fonticola

WP_094564569 337 QGSRqqq-----qeEDES 349 Herbaspirillum sp. meg3
1_pfamImport  73 VGADpqsggeggegSEGG 90 
WP_150696178 307 NGGDpdddd-pqanDTER 323 Pandoraea terrae
WP_234054928 419 QQPDh---------EEEG 427 Yersinia ruckeri
Q8X6E8       170 QPHEeqenegkfenDQKD 187 Escherichia coli O157:H7
WP_108439726 471 QPGQp--------hDEGE 480 Glaciimonas sp. PCH181
WP_026822623 328 NNSDe---------SGDE 336 son-killer infecting Nasonia vitripennis
WP_290607903 230 NEVLdns-----deSGEP 242 Arsenophonus sp. ENCA
WP_189535728 308 DQHSagq----hdsHDEE 321 Paludibacterium paludis
WP_024486137 315 QQKGqd------eiDDEV 326 Serratia fonticola
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