Conserved Protein Domain Family
HYR
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pfam02494: HYR 
HYR domain
This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Links
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Statistics
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PSSM-Id: 485768
Aligned: 13 rows
Threshold Bit Score: 78.1971
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O76536     882 VDTMMPMFtSCPNN-IVQSVELGVPGTVISWTTPTANDAAG---IASIVSNLQPGSFFTVGeSATVTYVATDNSGLTDnS 957  purple sea urchin
O76536     798 VDTTPPTV-NCANN-IAQTIELGSTSAVVNYAEPSATDISGt--AFLVSRSSSPGDSFPIG-STTVTYIFSDQSGNEApP 872  purple sea urchin
O76536     630 VDTTPPSV-NCPNN-VFQEVELGTSSAPVFFTEPTAFDISGq--ANLVTRTAAPGDSFPVG-TTSVSYIFSDNSGNEAeP 704  purple sea urchin
O76536     714 VDTTPPTV-NCINN-VAQTVQLGTGSTQVFFTEPTAFDISGq--TSLVTRTSAPGDSFPVG-TTSVTYIFTDASGNNAqP 788  purple sea urchin
O76536     967 VDTTPPSV-VCTNN-VFQTVELGTNPVQVFYTEPTASDISGq--ANLVSRTNVPGDSFPVG-TSTVTYVFADNSGNTAdA 1041 purple sea urchin
P90891    2293 KDRLPPTVlRCPKN-IRKGTTEDFTKVEWPDEDVAFFDNIG---VIRIEVNYHNGQQFGVG-ITTVRYVGFDAAGNSA-E 2366 Caenorhabditis e...
P78539     175 VDMEPPRI-KCPSV-KERIAEPNKLTVRVSWETPEGRDTADgilTDVILKGLPPGSNFPEG-DHKIQYTVYDRAENKG-T 250  human
O60687     177 VDIDPPKI-RCPHS-REKMAEPEKLTARVYWDPPLVKDSADgtiTRVTLRGPEPGSHFPEG-EHVIRYTAYDRAYNRA-S 252  human
O76536      40 TDTTPPVV-TVSSStITRQVEVGTPGVNVFFTEPTATDNSGq--AILISRTNQPGDFFSVG-QTIVTYTFQDPSGNPA-S 114  purple sea urchin
O76536     546 VDTTPPTV-TVSGGnIVRTVELGQSRLSVIYTEPTATDNSGe--ANLVSRTAQPGDLFPVG-TTTVEYVYQDPAGNEG-R 620  purple sea urchin
O76536     461 VDTTPPQV-FVTTGeVVRTAPFGSSGVNVFFTEPVAIDNSGt--ADLVSQTAQPGDFFPIG-STVVTYRYRDASGNEA-T 535  purple sea urchin
O76536    1051 QDTTPPTV-NCITN-IVRTVELGTSSVQVFYNEPTASDL-Gq--ASLVSRTAQPGDNFPVG-VNPVTYVFGDNSGNQAdP 1124 purple sea urchin
NP_500454 1540 PDTQPPVM-KCPDS---YTIPVGNSTKHVIFDMTTVDMVLHdtsNVSDVTFTPSEATLKIGeFEEVTAQAEDENGNRN-S 1614 Caenorhabditis e...

O76536     958 CSFTVTV 964  purple sea urchin
O76536     873 CVFTVTI 879  purple sea urchin
O76536     705 CTFTVTI 711  purple sea urchin
O76536     789 CTFNVVI 795  purple sea urchin
O76536    1042 CSFTITV 1048 purple sea urchin
P90891    2367 CTFDVTI 2373 Caenorhabditis elegans
P78539     251 CKFRVKV 257  human
O60687     253 CKFIVKV 259  human
O76536     115 GTVTINV 121  purple sea urchin
O76536     621 GQFTVTV 627  purple sea urchin
O76536     536 GTFTVTV 542  purple sea urchin
O76536    1125 CTFTITV 1131 purple sea urchin
NP_500454 1615 CKFQVAY 1621 Caenorhabditis elegans
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