2GIY,8V5P


Conserved Protein Domain Family
Herpes_gE
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pfam02480: Herpes_gE (This model is not part of the current CDD release)
Alphaherpesvirus glycoprotein E
Glycoprotein E (gE) of Alphaherpesvirus forms a complex with glycoprotein I (gI) (pfam01688), functioning as an immunoglobulin G (IgG) Fc binding protein. gE is involved in virus spread but is not essential for propagation. This entry represents the Ig-like domain of gE, identified as the Fc-binding domain.
Links
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Statistics
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PSSM-Id: 514956
Aligned: 7 rows
Threshold Bit Score: 252.048
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2GIY_A   9 RGVTVRMETPEAILFSPGETFSTNVSIHAIAHDd-QTYSMDVVWLRFDVPTSCAEMRIYESCLYHPQLPECLSPAD-APC 86  Human alphaherpesviru...
P09259 337 RGAEFHMWNYHSHVFSVGDTFSLAMHLQYKIHE--APFDLLLEWLYVPIDPTCQPMRLYSTCLYHPNAPQCLSHMN-SGC 413 Human herpesvirus 3 s...
P89475 215 RGVTVHMETLEAILFAPGETFGTNVSIHAIAHDd-GPYAMDVVWMRFDVPSSCADMRIYEACLYHPQLPECLSPAD-APC 292 Human herpesvirus 2 s...
P04488 220 RGVTVRMETPEAILFSPGETFSTNVSIHAIAHDd-QTYSMDVVWLRFDVPTSCAEMRIYESCLYHPQLPECLSPAD-APC 297 Human alphaherpesviru...
Q77MP7 182 ADIKLSLKNFKALVYHVGDTINVSTAVILGPSP--EIFTLEFRVLFLRYNPTCKFVTIYEPCIFHPKEPECITTAEqSVC 259 Marek's disease herpe...
Q6UDF4 210 DRDHVFVSMPRMHVAWPHGTTVLHPKMIIAAASwrPEYNFTYEWYAVPYDGYCATMRLFEACLYHPSAPACLDPAGhRGC 289 Psittacid herpesvirus...
8V5P_A  37 RGAEFHMWNYHSHVFSVGDTFSLAMHLQYKIHE--APFDLLLEWLYVPIDPTCQPMRLYSTCLYHPNAPQCLSHMN-SGC 113 Varicella-zoster virus

2GIY_A  87 AAST--WTSRLAVRSYAGCSRTn-PPPRC-SAEAHMEPVPGLAWQ---AASVNLEFRDASPQHSgLYLCVVYVNDHIHAW 159 Human alphaherpesviru...
P09259 414 TFTSphLAQRVASTVYQNCEHAdnYTAYC-LGISHMEPSFGLILH---DGGTTLKFVDTPESLSgLYVFVVYFNGHVEAV 489 Human herpesvirus 3 s...
P89475 293 AVSS--WAYRLAVRSYAGCSRTt-PPPRC-FAEARMEPVPGLAWL---ASTVNLEFQHASPQHAgLYLCVVYVDDHIHAW 365 Human herpesvirus 2 s...
P04488 298 AAST--WTSRLAVRSYAGCSRTn-PPPRC-SAEAHMEPVPGLAWQ---AASVNLEFRDASPQHSgLYLCVVYVNDHIHAW 370 Human alphaherpesviru...
Q77MP7 260 HFASniDILQIAAARSENCST---GYRRC-IYDTAIDESVQARLTfiePGIPSFKMKDVQVDDAgLYVVVALYNGRPSAW 335 Marek's disease herpe...
Q6UDF4 290 VVGTmtHDDLVGRVLMARCRGS--DLRTCePHVIHIKQKPMVSLG---RAVPELRVESAAHIPS-LYILVVKIDDSVAGW 363 Psittacid herpesvirus...
8V5P_A 114 TFTSphLAQRVASTVYQNCEHAdnYTAYC-LGISHMEPSFGLILH---DGGTTLKFVDTPESLSgLYVFVVYFNGHVEAV 189 Varicella-zoster virus

2GIY_A 160 GHITISTAAQYRNAVVEQPL 179 Human alphaherpesvirus 1 strain KOS
P09259 490 AYTVVSTVDHFVNAIEERGF 509 Human herpesvirus 3 strain Dumas
P89475 366 GHMTISTAAQYRNAVVEQHL 385 Human herpesvirus 2 strain HG52
P04488 371 GHITISTAAQYRNAVVEQPL 390 Human alphaherpesvirus 1 strain 17
Q77MP7 336 TYIYLSTVETYLNVYENYHK 355 Marek's disease herpesvirus type 1 strain MD5
Q6UDF4 364 AYTELMAEGSSPRVVIDIHM 383 Psittacid herpesvirus 1 Amazon parrot/1997
8V5P_A 190 AYTVVSTVDHFVNAIEERGF 209 Varicella-zoster virus
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