3MCU,1QZU,6M8T,6M8V,2EJB


Conserved Protein Domain Family
Flavoprotein

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pfam02441: Flavoprotein 
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Flavoprotein
This family contains diverse flavoprotein enzymes. This family includes epidermin biosynthesis protein, EpiD, which has been shown to be a flavoprotein that binds FMN. This enzyme catalyzes the removal of two reducing equivalents from the cysteine residue of the C-terminal meso-lanthionine of epidermin to form a --C==C-- double bond. This family also includes the B chain of dipicolinate synthase a small polar molecule that accumulates to high concentrations in bacterial endospores, and is thought to play a role in spore heat resistance, or the maintenance of heat resistance. dipicolinate synthase catalyzes the formation of dipicolinic acid from dihydroxydipicolinic acid. This family also includes phenyl-acrylic acid decarboxylase (EC:4.1.1.-).
Statistics
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PSSM-Id: 426775
Aligned: 89 rows
Threshold Bit Score: 78.5695
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3MCU_D         6 KRIGFGFTGSHCTYEEvXPHLEKLIA--E--GAEVRPVVSYTVQSTNTRFgegaewikkieeitgfkainsivgaeplgp 81  Bacillus cereus...
Q1IRZ9         1 MILTIATTGASGSIFL-RETLRRVEA--DqrVERVNFIASDSGLRVIAEElglsgrnglvqqllgssst----------- 66  Candidatus Kori...
Q0BU40        22 PRWGWALTGSGHYFTEcLDLIRSLDH--------VDLFVSKAAAEVVRmyhkd-----------------------lklp 70  Granulibacter b...
Q58140         2 LKIAWGITGCGDKLPEvVEIMKKLKNk-Y--NLDVDIYLSKNAKIVVKwyklwqvledefydlrv--------------- 63  Methanocaldococ...
O28754        10 KRVAWGITGSGDRLPEtVDVMLEVKKefP--DVEIAVYLSKAGAQVVKyyklmdtlkenfgavrv--------------- 72  Archaeoglobus f...
WP_012108775   1 MKILVCATGASFCKIA-VSLIKYLEQ-----NHEIYAIFSKNAKLVLNKEnnitelnfkkakil---------------- 58  Campylobacter h...
Q9PPF1         1 MKVLLGISGSSSVNLG-LKLLKNLEN-----QCELYCILTQGAKLNFKTEnqanleeicqenfkyth------------- 61  Campylobacter j...
WP_012012690   1 MKITVAISGASGVSLA-LNFIKQIPK-----DFEVFVVFSKSSKRALKLEnnistkelfkdeknit-------------- 60  Aliarcobacter b...
Q7VGG1         5 KKLVVAIGGASGVHLG-LKFIECVPD-----SIELFVVVSEGAKDVAKHEldynfkeqlfalkhkref------------ 66  Helicobacter he...
O26011         1 MKLVLGISGASGIPLA-LRFLEKLPK-----EIEVFVVASKNAHVVALEEsninlknamkdlrpsgt------------- 61  Helicobacter py...
3MCU_D        82 KI--------------------PLDCXVIAPLTGNSXSKFANAXTDSPVlxaakatlrngkpvvlavstndalglngvnL 141 Bacillus cereus...
Q1IRZ9        67 ---kiqqlnnddiganvasgsyPTDAMLVIPCSMGTLAKIANGIADQLIeraadvclkeqrklvlcvretplnkihirnM 143 Candidatus Kori...
Q0BU40        71 DNvrifrdttasaapvgnfyfgVYHTLVVAPATSNTVAKCVVGISDNLAtnvfaqagkcrvp--------------tivf 136 Granulibacter b...
Q58140        64 ------evnanapflvgklqtgKYDLFLVAPATANTTAKIAYGIADTLItnsvaqamkakvp-------------vyifp 124 Methanocaldococ...
O28754        73 ------eidantpflagqiqvgRYEFLLIAPATSNTVAKIAMGIADSLLanaaimglkayvp-------------lyimp 133 Archaeoglobus f...
WP_012108775  59 --------ndddlaqsvasgsfGIEKTIIAPCSSNTLAKIANGISDTLItraaaislkekkplilaprempfstislrqM 130 Campylobacter h...
Q9PPF1        62 ------flddknlslsvasgsfGIEKTIIAPCSISSLAKIHAGFADTLLmraaavalkerkklilgvrempfstlnlehM 135 Campylobacter j...
WP_012012690  61 ------ifkdsdigasiasgsfKVDKMIILPCSQNTLAKCAVGIADSLItraftvmlkekreiviaprempfntislknM 134 Aliarcobacter b...
Q7VGG1        67 -----ciynenemdspiasgsfGIDAMAVVPTSMNLLAKIANGLCDELIsrcasvmlkerrklllapremplspialeqM 141 Helicobacter he...
O26011        62 ------ffneqdihasiasgsyGIHKMAIIPASMDMVAKIAHGFGGDLIsrsasvmlkekrplliapremplsaimlenL 135 Helicobacter py...
3MCU_D       142 XRLxATKNIYFVP-------FGQDAPEKKPNSXvarxell---edtvleaLQGKQLQPV 190 Bacillus cereus ATCC 14579
Q1IRZ9       144 GLA-ADAGATIFPvip--afYDQPQSPDQMASQ-----------------FVCRVLQHL 182 Candidatus Koribacter versatilis Ell...
Q0BU40       137 acdtapemDTEAPsgm-vkvYPRRIDLQNTERLrdfeattvvetyedlqaAIDGRRSAF 194 Granulibacter bethesdensis CGDNIH1
Q58140       125 pdnkkgtvETILPgnkkltlYMRDVDVENVERLrrmegievldkpediekVILKHIEVK 183 Methanocaldococcus jannaschii DSM 2661
O28754       134 sdykegevITKLPdgrdlrlRVRKEDVEHVRKLaqmdgvtilekpedipkVFRKHFGKS 192 Archaeoglobus fulgidus
WP_012108775 131 SEL-SALGVIIAPpva--adYFSPENLDDLEKF-----------------FIGKWLDLL 169 Campylobacter hominis
Q9PPF1       136 LKL-SQMGVIIAPpii--asYSKANNLEQMENF-----------------IAGKWLDLL 174 Campylobacter jejuni subsp. jejuni N...
WP_012012690 135 LIL-SKLGVTIAPpil--gyYSNQQSLEDMENF-----------------LVGKWFDLL 173 Aliarcobacter butzleri
Q7VGG1       142 SKL-SLLGVIIAPpsv--gyYAKPNDLESMERF-----------------FIGKWFDAL 180 Helicobacter hepaticus
O26011       136 LKL-SHSNAIIAPpmm--tyYTQSKTLEAMQDF-----------------LVGKWFDSL 174 Helicobacter pylori 26695
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