7YQD,7DR6,7DR6,6DFK


Conserved Protein Domain Family
PA28_C
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pfam02252: PA28_C (This model is not part of the current CDD release)
Proteasome activator PA28, C-terminal
Proteasome activator 28 (PA28), also known as 11s regulator of REG, binds to the 20S proteasome and simulates peptidase activity in an ATP-independent manner. This entry represents a the C-terminal domain found in PA28 subunits, including PA28alpha/beta/gamma (also known as Proteasome activator complex subunit 1-3).
Links
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Statistics
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PSSM-Id: 514812
Aligned: 54 rows
Threshold Bit Score: 185.028
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7YQD_A       108 MLKSNQQLV-DIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITR 186 human
XP_007389597 113 QMVANQHIQ-KVHGILKKECEELADSIDKVKLWINLSMPKIEDGDNFGVQIQEEVLNELHRSQESAYNLRDAARQSHFNR 191
EPT01604     126 LVTANQYVD-KVHAIVKKECEQLADSCDKVKLWVNLSMPKIEDGDNFGVQIQEEVLTELHRSQESAYNIRDAGRQDHLHR 204
9_pfamImport   1 LVHANAHII-KLNADIKKECTQLADLCEKVKLWVNLTMPKSNFRHFLGVQIQEEVLTELHRSQESAYNLRDGIRQDYLAR 79 
ESK98084      98 LVKSNFHAK-SLHDVVKKECEEIATLIDHIKLWVTLRMPRIEDGDNFGVQVQEEALAELHRAQESAYNIRDVPRQDYLSR 176
XP_003038805  98 SVAANQRLL-GLHDVIKRECEQLGTLVEQVKLWITLTMPKIEDGDNFGVEIQTEVLNELDRVHQSAYNLRDLARQHHLER 176
XP_001883313  45 LVYDNPRIQ-KIHEVISKQVEEMMLLSEQVEVWIILTIPQIEDGDNFGVQVQEKVLDQILIADKSATIFRSAALDHHLDH 123
XP_011386502 117 VVHTPAFLM-RAFDELRIEWDQLIETMDSLKIYINLQMPQIEDGDTFGVSIQEEALNEIIRTQESAYTLISTPFTYHSTR 195
XP_001829111 109 HVKANDHMTnKIYNFVKKECEELADLTDQVRLWVTLTLPKIEDGDNFGVHVQEEVLGELQRAQESALAIRDLPRQDHLTR 188
XP_047809862 112 HVSSNPRVN-AHYIFLRTHWEELIDITNAIKIHINLLVPKIEDGDTFGVQVQEECLSELSRAQDSGYNLLEAQLKHNMSR 190 Puccinia striif...

7YQD_A       187 AKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAET 252 human
XP_007389597 192 AKLCSKILKYPHIEDYLLALKEHDEKQLYVAKQNLYDIRNVYAILTDILHKNIGKLRTPKGNNATG 257
EPT01604     205 AKICSKIVKYPHLEDYALALKEHDEKQIYVARQNLFDLRNVYAILTDILHKNIAKIRSPKGNNLSG 270
9_pfamImport  80 AKICSKVIKYPHVEDYTLALKEQDEKQLYLARQHIVDIRNVYAILTDIIHKNINKICSPKGNNGVG 145
ESK98084     177 AKICSKLIKYPHVEDYTLALQEHDSKQIYYARQRLYDIRNLYAALTDVLHKNIAKIRAPKANNRTG 242
XP_003038805 177 AKICSKLIKYPNIEDYTMALREHDEKHVRVARENLTDVRDLYAVMTDLIHKNITKIRAPKANNNSG 242
XP_001883313 124 ARICSKLCKYPNVKDYARALEEHDKRQIYIARERLREIRNEYAILVDVIQKNISKIRVPKANHGGD 189
XP_011386502 196 GDLAAKLVKFPGVQDYEKAILEHDRKTVYRLKMYLTDIRNMYAVVFDIVKKNIGKISKPKSGNQMG 261
XP_001829111 189 AKICSKLIKYPNIEDYALALRDHDEKQFYFARQHLYDIRNVYASITDMMQKNISKIRTPKSNNRAA 254
XP_047809862 191 AKLASKLIKYPNVEDYQIALQEHDRKSIFLCRQHLLDLRNIYALLTDLLHKNIVKITKPKGANSDG 256 Puccinia striiformis f. sp. t...
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