1AYE,3GLJ,3DGV


Conserved Protein Domain Family
Propep_M14

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pfam02244: Propep_M14 
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Carboxypeptidase activation peptide
Carboxypeptidases are found in abundance in pancreatic secretions. The pro-segment moiety (activation peptide) accounts for up to a quarter of the total length of the peptidase, and is responsible for modulation of folding and activity of the pro-enzyme.
Statistics
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PSSM-Id: 426674
Aligned: 342 rows
Threshold Bit Score: 39.0999
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1AYE_A         10 LEIVPSNE-EQIKNLLQLEaqEHLq---LDFWK--SPTTPGETAHVRVPF-VNVQAVKVFLESQGIAYSIMIEDVQVLLD 82  human
EFP00953       28 YRLLPKTQ-TDFQAIQRLY--KNAtdhdLNFWK--TGKDKHGFWDVMVEL-NNEKFLMDYLQINDISHVKTIEDVEKLIS 101 Caenorhabditis...
Q6A576         26 YRLLPKSQ-TDFQAIQRLY--KNAtdhdLNFWK--TGKDKHGFWDVMVDM-KNSKYFLDFLQVNDISYIKTIDDVEGLIT 99  Caenorhabditis...
Q9XU75         37 IHVSAHDE-QSLHLIKQLQl-NDFky-dLDFWK--SPSSISDKADIMVKRgKSERMLRQILSFANVTVSMSVPDVEKLIM 111 Caenorhabditis...
XP_015836633   32 YRLTPRSQ-KAVQALRELE--ENG----YDFWTsvR--GVNQPVDVMVPP-HYKHRFNDFIRLNEFDAQIYIPDVQKLID 101 red flour beetle
EFX83249      396 RWVNAKNK-VALEVLTKLY--NERsd-vYDFWT--EPRNINRAVDIMVPP-AFGSTFTSLMQAFDVDYKVRIADVQSTIE 468 common water flea
EFX83250       27 YEVTAKNK-ASFDVLVKLY--NERsd-iYDFWT--EPRNVDFKTDVMVPP-AYTKTFVNLMQVFDMEYHIKIADVQNEIE 99  common water flea
EFX83248       27 FQVTPKDA-ASYDALARL----SDse-iYDFWT--DLRTIGHSTDIMVPP-AYVSLFVDLMYAYSMEYRVKMVDVQTVLD 97  common water flea
EFX83247       27 FQVTPKDQ-SSFEAMVQLY--EQSe--nYDFWI--APRGIDFAMDIMVPP-AYTSVFVDLMHAYSMEYRVEMIDVQTVLD 98  common water flea
27_pfamImport   1 FYVAASSInSTKANLGKLG--IQHr---YVFIS---------CCEYFSKL-DWQHCHLSGVCALSLFFRILMGDVQELIK 65 
1AYE_A         83 KE 84  human
EFP00953      102 KH 103 Caenorhabditis remanei
Q6A576        100 KH 101 Caenorhabditis elegans
Q9XU75        112 RN 113 Caenorhabditis elegans
XP_015836633  102 NE 103 red flour beetle
EFX83249      469 EG 470 common water flea
EFX83250      100 QS 101 common water flea
EFX83248       98 MA 99  common water flea
EFX83247       99 MA 100 common water flea
27_pfamImport  66 KQ 67 
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