Conserved Protein Domain Family
WH2
?
pfam02205: WH2 (This model is not part of the current CDD release)
WH2 motif
The WH2 motif (for Wiskott Aldrich syndrome homology region 2) has been shown in WASP and Scar1 (mammalian homologue) to be the region that interacts with actin.
Links
?
Statistics
?
PSSM-Id: 514779
Aligned: 41 rows
Threshold Bit Score: 31.6167
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
O75128 1106 DTSLHSALMEAIHSAGGkdrLRKTAEHTGEG 1136 human
Q95107  402 PAGSKAALLDQIREGAQ---LKKVEQNSRPV 429  domestic cattle
P70315  445 PGGGRGALLDQIRQGIQ---LNKTPGALENS 472  house mouse
Q95107  430 SCSGRDALLDQIRQGIQ---LKSVTDAPEST 457  domestic cattle
Q17795  530 GGDARGDVMAQIRQGAQ---LKHVDAAAEQE 557  Caenorhabditis elegans
Q9Y6W5  433 VSDARSDLLSAIRQGFQ---LRRVEEQREQE 460  human
Q92558  494 ISDARSVLLEAIRKGIQ---LRKVEEQREQE 521  human
Q12446  544 GDAGRDALLASIRGAGGigaLRKVDKSQLDK 574  Saccharomyces cerevisiae S288C
P29536  571 EKNSRDQLLAAIRSSNLk-qLKKVEVPKLLQ 600  human
Q8BVA4  566 EKNSRDQLLAAIRSSNLk-qLKKVEVPKLLQ 595  house mouse
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap