Conserved Protein Domain Family
Transp_cyt_pur

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pfam02133: Transp_cyt_pur 
Permease for cytosine/purines, uracil, thiamine, allantoin
Statistics
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PSSM-Id: 251109
Aligned: 14 rows
Threshold Bit Score: 253.465
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P05316 103 PVEKERRVWSWYNYCYFWLAECFNINTWQIAATGl-QLgLNWWQCWITIWIGYGFVGAFVVLASRVGSAYHLSFPISSRA 181 Saccharomyces cerevis...
P0AA82  11 PVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG--TG-LSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARF 87  Escherichia coli K-12
O14035  55 PVPKSQRVWGPWNYVAFWLADSVNVNTWMIAGTAv-ESgLSWWEAWITVWVGYTIAAFILTIAGRAGAVYHISFPVLSRS 133 Schizosaccharomyces p...
Q10279  48 PVPPSKRLWGPWNFISFWLADAVNINTWMISATAi-ELgLNWWEAWICVWVGYLICGILVATTGRPGAVYHISFPVLSRS 126 Schizosaccharomyces p...
O69811  47 PVPVEGRTWTTYNFSALWVGMAHNTASWTLASGLi-AVgMDWKQAVFTIALANLIVLAPMLLTGHAGPKYGIPFPVFARA 125 Streptomyces coelicolor
P94575  20 PLGQEKRTWKAMNFASIWMGCIHNIPTYATVGGLi-AIgLSPWQVLAIIITASLILFGALALNGHAGTKYGLPFPVIIRA 98  Bacillus subtilis sub...
P75712  19 PKTQSQRTWKTFNYFTLWMGSVHNVPNYVMVGGFf-ILgLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRA 97  Escherichia coli K-12
Q9ZBQ0  18 QVPDHERTARTRELFPTWVGANISVLLLTMGASLvvAYrLNFWQALVVAGAAPVVSYGLVGLIGIAGKRGGAPGMALSRA 97  Streptomyces coelicolor
O86506  10 TIPEAERTSGPRDLVSILLGSNLCLGVIVFGWLPp-SFgLGWWASVSSVVAGTVVGTVFTAPLALISLRTGTNLSTSSGA 88  Streptomyces coelicolor
P94369  10 YIPNEERHGKAKDLFPVWFGANMHITTLVTGTIPv-AMgLNLFWSVAAIICGTLIGAIFMASHSAQGPQLGIPQMIQSRA 88  Bacillus subtilis sub...
P05316 182 SFGIFFSLWPVINRV-VMAIVWYSvqayIAATPVSLMLKSIfgkdlqdkipdhfgspnATTYEFMCFFIFWAASLPFLLV 260 Saccharomyces cerevis...
P0AA82  88 SFGVKGSWLPSLLLG-GTQVGWFG----VGVAMFAIPVGKA-----------------TGLDINLLIAVSGLLMTVTVFF 145 Escherichia coli K-12
O14035 134 SFGIWGSLWPILNRA-VMACVWYGvqawIGGECVTLMIRSIwpsfship--ntmaksgTETYQWVGFFIFWLISNVAIWF 210 Schizosaccharomyces p...
Q10279 127 SFGTWGSLWPILNRS-VLACVWYGvqawIGGECVVLMIRSIwpsfship--ntmaksgTETYQWVGFFIFWLLSNIAIWF 203 Schizosaccharomyces p...
O69811 126 SFGIRGANLPAVVRA-LVACGWFGiqtwIGGEAIYFLAGKLigdgwtn----agtfggHAWTMWLSFAIFWALQVAIIYR 200 Streptomyces coelicolor
P94575  99 SYGIYGANIPALLRA-FTAIMWLGiqtfAGSTALNILLLNMwpgwgeig--gewnilgIHLSGLLSFVFFWAIHLLVLHH 175 Bacillus subtilis sub...
P75712  98 SYGVRGALFPGLLRGgIAAIMWFGlqcyAGSLACLILIGKIwpgfltlg--gdftllgLSLPGLITFLIFWLVNVGIGFG 175 Escherichia coli K-12
Q9ZBQ0  98 VFGQRGNLLPGSLIW-VARWGWETinavTGAYALLTVLDIVfgi------------raNSVLDMVTLLAFVVATFAISGL 164 Streptomyces coelicolor
O86506  89 QFGVRGRLVGSVVGL-LLALGYTAltvwIGGDVMAGVLGRLfglpqg------gatyaVVYGLLAAATVAGAVYGYRVLL 161 Streptomyces coelicolor
P94369  89 QFGVIGAILPLFLVM-FIYLGFFAsstiLAAGTLSSFVPIPgsws---------iiglSAVCFLLTIFGHDLIHKMQKIL 158 Bacillus subtilis sub...
P05316 261 PPHKIRHLFTVKAVLVPFASfGFLIWAIRRAHGrialGSLTD--VQPH-GSAfs-waFLRSLMGCMANFSTMVINAPDFS 336 Saccharomyces cerevis...
P0AA82 146 GISALTVLSVIAVPAIACLG-GYSVWLAVNGMG----GLDALkaVVPAqPLD-----FNVALALVVGSFISAGTLTADFV 215 Escherichia coli K-12
O14035 211 PVYQIRHLFTAKSFLAPPAAiAFLIWALVKAHGa---GDAIHakTQLS-TWNhg-waVTAGIISCLDNFATLIVNNPDFT 285 Schizosaccharomyces p...
Q10279 204 PVHQIRHLFTFKAIVAPPAAiAFLIWALVKAHGa---GPVIHepTKLG-QYEha-wvVINGIVTCIDGFATLIVNNPDFA 278 Schizosaccharomyces p...
O69811 201 GMETIRRFENWAAPFVLVGAfVMLWWMADKAGGf---GPLFDqpSRLG-WGGdfwklFWPSLMGMIGFWSTLSLNIPDFT 276 Streptomyces coelicolor
P94575 176 GMESIKRFEVWAGPLVYLVFgGMVWWAVDIAGGl---GPIYSqpGKFHtFSEtf-wpFAAGVTGIIGIWATLILNIPDFT 251 Bacillus subtilis sub...
P75712 176 GGKVLNKFTAILNPCIYIVFgGMAIWAISLVGI----GPIFDyiPSGIqKAEnggflFLVVINAVVAVWAAPAVSASDFT 251 Escherichia coli K-12
Q9ZBQ0 165 GINAVQKCNKYAAYLFGAFSvLVLGYLVVDTDW----SAVFDrsAGSVaA-------MITGVGLIAAGGVSWIPSAPDFT 233 Streptomyces coelicolor
O86506 162 AMSRVLAYGMTALLVLGVIAyAPDFTTAALPEA----GGYLLggFWPTw--------LLAAVAAGLSGPIAFITLLGDYT 229 Streptomyces coelicolor
P94369 159 SWTSFAVFFAATILIFQLPi-PAGSWIPGAIDL-----PIFLv--------------aVSAVATWQLAYAPYVA---DYS 215 Bacillus subtilis sub...
P05316 337 RFSKNPNSALWSQLVCIPFLFSITCLIGILVTAAGYEI-YGINYWSPLdvlekflQTtynkgtragvFLISFVFAVAQLG 415 Saccharomyces cerevis...
P0AA82 216 RFGRNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMA-DISDVMIAQ-------GL----------LLPAIVVLGLNIW 277 Escherichia coli K-12
O14035 286 RFATTPNAPIFPQLITIPMGFGITTLIGVLVGSASKSI-YGENIWNPLdllksflDHsnhhgvragvFFISTGLCLAQLG 364 Schizosaccharomyces p...
Q10279 279 RFATTPGAVHWPQIITVPLAFGVTSLIGVLVSSASKAI-YGTTLWDPTqllasflDHsnahgvragvFFIAFGLCIAQLG 357 Schizosaccharomyces p...
O69811 277 RYGKSQRAQTRGQALGLPTTMTLFAFLSVMVTSGSQAV-YGEPIWDPVqlaaktdNVvg-------lLFALVTVLVATLS 348 Streptomyces coelicolor
P94575 252 RFAETQKEQIKGQFYGLPGTFALFAFASITVTSGSQVA-FGEPIWDVVdilarfdNPyv-------iVLSVITLCIATIS 323 Bacillus subtilis sub...
P75712 252 QNAHSFREQALGQTLGLVVAYILFAVAGVCIIAGASIH-YGADTWNVLdivqrwdSLfa-------sFFAVLVILMTTIS 323 Escherichia coli K-12
Q9ZBQ0 234 RYLPRTASSKGIVGVTVGGAGIVVLPMVLMGAVMAVSTpDLASAADPVsflgeilPTw--------iAVPYLLIALIGML 305 Streptomyces coelicolor
O86506 230 RYISPARHSSRRVLRATWLGLTLGLLVPQLFGTFTAYAaGAALDYAGPlvd--asPTw--------yLVPLLLAASAGSV 299 Streptomyces coelicolor
P94369 216 RYLPVKTPASKTFWYSYAGTSVSSIWMMLLGALLTTSL-PDFTANSGSqivqlfgPFs---------FIMLIIVLFGQMA 285 Bacillus subtilis sub...
P05316 416 TNISANSLSCGTDMSAIFPk---fINIKRGSLFCAAMALCICPWnLMATSSKf---TmaLSAYAIFLSSIAGVVCSDYFV 489 Saccharomyces cerevis...
P0AA82 278 TTNDNALYASGLGFANITG-----MSSKTLSVINGIIGTVCALW-LYNNFVG----W--LTFLSAAIPPVGGVIIADYLM 345 Escherichia coli K-12
O14035 365 VNIAANTVSAGNDTSALCPm---fINIRRGGYIASIIGICMCPWnLLSSSNSf---AnsLSAYAVFLSSFAGILIADYFV 438 Schizosaccharomyces p...
Q10279 358 VNIAANSVSAGNDLSALLPt---vINVRRGGYIASIIALCMCPWnLLSSNNNf---TtyLSSYSVFLSSFAGVIIADYYF 431 Schizosaccharomyces p...
O69811 349 VNIAANLVSPAFDFSNVAPr---rVSFRAGALITSVLAVLIFPWkLYSDPQGy--iFtwLGLVGGLLGTVAGILIADYWI 423 Streptomyces coelicolor
P94575 324 VNVAANIVSPAYDIANALPk---yINFKRGSFITALLALFTVPWkLMESATSv---YafLGLIGGMLGPVAGVMMADYFI 397 Bacillus subtilis sub...
P75712 324 TNATGNIIPAGYQIAAIAPt---kLTYKNGVLIASIISLLICPWkLMENQDSi---YlfLDIIGGMLGPVIGVMMAHYFV 397 Escherichia coli K-12
Q9ZBQ0 306 LINSMSMYSAGFTAQTLGFk----VPRHWAVSVNAVISLVFGGVlMLVATSFmgsfIafLSLLAVAFSAWVGVFGADMLR 381 Streptomyces coelicolor
O86506 300 GNAGLMLYSMGLDLDAILPr----ASRARATCAVAVVATACVFAgHYAWQAQsa-mTsfVLLLTAIGTPWAVITMIGSVR 374 Streptomyces coelicolor
P94369 286 INVFNLYGAFMSTTTTLEPflklkVTPKVRIIMILGVTLVGTVLsLLGQSNFmelfLnfIFFISYFLIPWTAINLVDYYF 365 Bacillus subtilis sub...
P05316 490 VRRGYIKLTHIYShqkgsfymygnrFGINWRALAAYLCGVAPCLPGFIaevg-apaiKVSDGAMKLYYLSYWVG 562 Saccharomyces cerevisiae S288C
P0AA82 346 NRRRYEHFATTRM------------MSVNWVAILAVALGIAAGHWLPG---------IVPVNAVLGGALSYLIL 398 Escherichia coli K-12
O14035 439 IRKGYLKVDALYTinpne--pywftYGINLRAFASYICGLLINVVGLAgav----gdKVPKAALTMNNIAYLLG 506 Schizosaccharomyces pombe 9...
Q10279 432 VRKGLIRVAPLYSsssss--pyyfwKGINFRAFASYICGMLINIVGMAgst----gqKVPKVANTMFNLNYFLG 499 Schizosaccharomyces pombe 9...
O69811 424 LRRARLHLVDLYRrggr----ywyeGGWNWRAVLAFVVGGVLAVGGADfhpl--vdgRPVPFLEPLADYGWAVG 491 Streptomyces coelicolor
P94575 398 IRKRELSVDDLYSetgr----yvywKGYNYRAFAATMLGALISLIG-----------MYVPVLKSLYDISWFVG 456 Bacillus subtilis subsp. su...
P75712 398 VMRGQINLDELYTapgdy---kyydNGFNLTAFSVTLVAVILSLGG-----------KFIHFMEPLSRVSWFVG 457 Escherichia coli K-12
Q9ZBQ0 382 GREYDGEALADTGrtsa----ywyrGGFSPAAVVAWAVGLAAGLMFTTsd------wFTGPLATDNFVGEYGLG 445 Streptomyces coelicolor
O86506 375 CGGVYDADALQVFnrrarggiywyrSGWNVPATAAWAVGALVGVLAVSlpsyegpllSLTGGVDCSFLLSGLVG 448 Streptomyces coelicolor
P94369 366 VRHGKYQVKAMFDvng-------pygKVNWITTIAFVLSILLEIPFINtsf----yiGPLAKMFGGGDIAWIIG 428 Bacillus subtilis subsp. su...
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