pfam02132: RecR_ZnF (This model is not part of the current CDD release)
RecR, Cys4-zinc finger domain
The bacterial protein RecR is an important regulator in the RecFOR homologous recombination pathway during DNA repair. It acts with RecF and RecO forming a complex that facilitates the loading of RecA onto ssDNA. RecR is a zinc metalloprotein consisting of a N-terminal helix-hairpin-helix (HhH) motif, a middle region containing a zinc finger motif and a Toprim domain (pfam13662) and a C-terminal domain comprising a Walker B motif and a C-terminal helix. This is the zinc finger motif, which consists of four strictly conserved cysteine residues which coordinate a zinc ion. This motif is the most conserved domain in RecR proteins and plays a structural role stabilizing the 3D structure of the protein.
Jiyao W et al.(2023). "The conserved domain database in 2023.",