6H6P,4JGX,3CNU


Conserved Protein Domain Family
SCP2

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pfam02036: SCP2 
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SCP-2 sterol transfer family
This domain is involved in binding sterols. It is found in the SCP2 protein, as well as the C-terminus of the enzyme estradiol 17 beta-dehydrogenase EC:1.1.1.62. The UNC-24 protein contains an SPFH domain pfam01145.
Statistics
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PSSM-Id: 426574
Aligned: 106 rows
Threshold Bit Score: 53.4051
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6H6P_D             26 LNTFLYRs------pALKTARSRLLGk------VLRVEVKGFST-SLILVFS---ER-QVDV----LGEWA-GDAD--CT 81  Escherichi...
WP_012116416        4 LSSLVEAm------rERSDALSELGY-------KVRFDLTDTGE-AILLDAT---GG-AVEVge-gSG-----EAD--AV 57  Xanthobact...
Q9YAH5             12 AEEFCKTlds---seKYRSAAKGWVH-------PILFKISDGGQ-GFILDLK---DGrCLGV----QWFDDtSRADapVI 73  Aeropyrum ...
WP_011777807       12 araYRDLwnd---saEIRQGAKELSM-------LIEWRVQDANDqVSQLEIT---DG-EAIYg---GVQIQgRKPD--FV 72  Mycoliciba...
jgi:HY04AAS1_0102  10 IKAYKDQwnk---neKLKNDLKNFSA-------KLKYYIISKENeAVELIIK---NGeAISC----GMADG-KDYD--FE 69  Hydrogenob...
O66500             15 IKAYAEEwnk---neKLMNDLKNFSA-------SIKYYVEGKEN--DAVELI---IE-KGKAvs-aGKADPnKRYD--FE 75  Aquifex ae...
WP_012513600       42 LVGMASSss-----eWRGAPVRKLFL--------YRKDCSPRKQiELYIQNM---NG-KAECiyggWAKDGrTGND--FL 102 Hydrogenob...
O66445             26 AKQFCEVwnntpelvEKLGKSESWTEvperklfLYRKDCGPEKQ--IQLTIKnenGR-AVCVyg-gWKKDEkTDND--FL 99  Aquifex ae...
Q2SJ40              7 FQQLKDNf--------nADAASDLDL-------VFQFSIEDAd--NYHLVVK---NG-GCELiq-gDHD----DPS--VT 58  Hahella ch...
3CNU_A              8 IKKMCDLqns---neEIQKEMAGWSG-------VVQYKLDGE---EFYVEYKs--DG-TCEFke-gVHS----SPT--FT 64  Archaeoglo...
6H6P_D             82 VIAYASVLPKLRDRQ-QLTALIRSGELEVQGd-IQVVQNFVALA 123 Escherichia coli K-12
WP_012116416       58 LKLSTDTLDKLITGRmGPLMAFSTGRLKVQGs-QGVALKLAGLL 100 Xanthobacter autotrophicus
Q9YAH5             74 ISGRLSDWLDVINGKvNPLTALLTRRLRIEKgdLSLILRYSAAA 117 Aeropyrum pernix
WP_011777807       73 LTATASVWHRVADGElGVANAIATRKIKFVGp-VKVAMANMAVL 115 Mycolicibacterium vanbaalenii
jgi:HY04AAS1_0102  70 MWATLEDWKSLATGQmGPKAAMLTKKLKFKGs-MITAMKYMGAF 112 Hydrogenobaculum sp. Y04AAS1
O66500             76 LWASLENWKKLATGEmGPRAAMLTKRLKFKGs-MITAMKYMGAF 118 Aquifex aeolicus
WP_012513600      103 MYATTKHWIEMGRGEyGPMHAMMFGELSFSGp-KFVAMANMGPF 145 Hydrogenobaculum sp. Y04AAS1
O66445            100 MYADTKRWLEMGRKEyGPMKAMLFGRLKFEGp-RFVAMKNMGPF 142 Aquifex aeolicus
Q2SJ40             59 LIMNSDTLKGIVSGEtDGMQAFMAGDLRAEGd-MMLAMKLGQLF 101 Hahella chejuensis KCTC 2396
3CNU_A             65 VVAPPDFWLAVLKGQeDPVSGFMMGKYRIEGn-IMEAQRLAGVI 107 Archaeoglobus fulgidus DSM 4304
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