5FFO,3V4P,5E6S,3V4P,4WK0,5FFO,5E6S


Conserved Protein Domain Family
FG-GAP

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pfam01839: FG-GAP 
FG-GAP repeat
This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats.
Statistics
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PSSM-Id: 460357
Aligned: 174 rows
Threshold Bit Score: 28.6303
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5FFO_A  276 FGFSVAATDINGDDYADVFIGAPLFmdrgsDGKLQEV 312  human
Q7NKM7  269 NPKSVALGDVDGDGDLDIATANGGSfp-dyPGSVTVL 304  Gloeobacter violaceus
Q7NKM7  119 SPSSAVLGDVDGDGDLDIATANSGSvy-qvTGSVTVL 154  Gloeobacter violaceus
Q7NKM6   49 RPTSVALGDIDGDGDLDIATASGDYa---dPGNVSVL 82   Gloeobacter violaceus
Q7NN22  145 PLSSVALGDLDGDGDLDIVTTAPGFyg-lnNADVPVL 180  Gloeobacter violaceus
Q7NM76  214 GLNAVTVGDLDGDGDLDVAITSSGFg---dNGYVVVF 247  Gloeobacter violaceus
Q7NLX4  105 SVEALALGDVDGDGDLDIVTNNTFT-----SFAVSVL 136  Gloeobacter violaceus
Q7NLX5  473 APIGVAVGDVNGDGNLDIVTASSLS-----QENISVL 504  Gloeobacter violaceus
Q9KTH2  309 ARYSPAVGDLDGDGIVEIVTTNn------rDQFITIL 339  Vibrio cholerae
Q7NFS7  462 YSSSAALGDIDGDGDLDLVTASSRDf----DQGIGIF 494  Gloeobacter violaceus
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