6PPB,7BSI,6Q1F,8TEP,5ZAP


Conserved Protein Domain Family
Herpes_V23
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pfam01802: Herpes_V23 (This model is not part of the current CDD release)
Herpesvirus VP23 like capsid protein
This family consist of various capsid proteins from members of the herpesviridae. The capsid protein VP23 in herpes simplex virus forms a triplex together with VP19C these fit between and link together adjacent capsomers as formed by VP5 and VP26. VP3 along with the scaffolding proteins helps to form normal capsids by defining the curvature of the shell and size of the particle.
Links
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Statistics
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PSSM-Id: 514515
Aligned: 16 rows
Threshold Bit Score: 265.787
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6PPB_6   6 SIVVNLTSRLFADELAALQSKIGSVLPLGDCHRLQNIQALGLGCVCSRETSPDYIQIMQYLSKCTLAVLEEVRPDSLRLT 85  Human herpesvirus 8 s...
F5HGN8   6 SIVVNFTSRLFADELAALQSKIGSVLPLGDCHRLQNIQALGLGCVCSRETSPDYIQIMQYLSKCTLAVLEEVRPDSLRLT 85  Human herpesvirus 8 s...
Q01008   6 TIIVSLTSRLFADEITKLQKKIGSILPLQDPHKLQSLDTLGLNAVCSRDVFPDYVHMFSYLSKCTLAILEEVNPDNLILT 85  Herpesvirus saimiri (...
Q9QJ27   3 TVYCTFDHKLSLSDISTLCKLMNIVIPIPAHHHLIGSGNLGLYPIVSSN--KDYVHIRNVLRTMVVTILQKVEGNQLVLR 80  Human herpesvirus 6 s...
F5HIN9   7 NIFCTFDHKLSIADVGKLTKLVAAVVPIPQRLHLIKHYQLGLHQFVDHT--RGYVRLRGLLRNMTLTLMRRVEGNQILLH 84  Human herpesvirus 5 s...
Q6UDI3  10 EVKITLPGNLTRDEEDRLRCLTGTILMAPSLRRCLFLHDVDRNSYYVHGSEPDYATSLAAYRRRFPLLVTAVGRQELSAV 89  Psittacid herpesvirus...
Q9E6P9   8 iVEIELPCKLSTCDANLLQRCEGRVLFLPFVRARVLLKDVDYKSFYIAGTEPDTLSLLSTFKTRFAAVITRALPGRMSAV 87  Marek's disease herpe...
P89441   7 EADIAIPSGISRPDAAALQRCEGRVVFLPTIRRQLALADVAHESFVSGGVSPDTLGLLLAYRRRFPAVITRVLPTRIVAC 86  Human herpesvirus 2 s...
6Q1F_6   3 TVYCTFDHKLSLSDISTLCKLMNIVIPIPAHHHLIGSGNLGLYPIVSSN--KDYVHIRNVLRTMVVTILQKVEGNQLVLR 80  Human herpesvirus 6 s...
8TEP_U   7 NIFCTFDHKLSIADVGKLTKLVAAVVPIPQRLHLIKHYQLGLHQFVDHT--RGYVRLRGLLRNMTLTLMRRVEGNQILLH 84  Human herpesvirus 5 s...

6PPB_6  86 RMDPSDN----LQIKNV-YApfFQWDSNTQLAVLPPLF-SRKdSTIVLESNGFDIVFPMVVPQQLGHAILQQLLVYHI-Y 158 Human herpesvirus 8 s...
F5HGN8  86 RMDPSDN----LQIKNVyAPf-FQWDSNTQLAVLPPFF-SRKdSTIVLESNGFDLVFPMVVPQQLGHAILQQLLVYHI-Y 158 Human herpesvirus 8 s...
Q01008  86 RLDPSET----YQIKNVyEPm-FQWDGFSNLTVIPPVF-GRQqATVTLESNGFDLVFPSVVPSDLAQAIIGKLLLYNL-Y 158 Herpesvirus saimiri (...
Q9QJ27  81 KPMTGQQ----YAIKNT-GP--FPWEKGDTLTLIPPL--STHsEEKLLKLGDWELTVPLVVPTAIAAEINIRLLCIGL-I 150 Human herpesvirus 6 s...
F5HIN9  85 VPTHGLL----YTVLNT-GP--VTWEKGDALCVLPPLFhGPLaRENLLTLGQWELVLPWIVPMPLALEINQRLLIMGL-F 156 Human herpesvirus 5 s...
Q6UDI3  90 SLSIGCPk--gLNFRNT-GP--FQLLNGSNVSLIPPIG-GRW--RVELLSCGSVIEPAMTIPTEVGSELLGKILA-GMtY 160 Psittacid herpesvirus...
Q9E6P9  88 VLGMGSIpn-gLALQNT-GP--FDLCNGDTVCLMPPIF-PNVcCRIRLESIDTELLFPVTVPTRLANEILAKTLSRAI-- 160 Marek's disease herpe...
P89441  87 PVDLGLThagtVNLRNT-SP--VDLCNGDPVSLVPPVF-EGQaTDVRLESLDLTLRFPVPLPTPLAREIVARLVARGI-- 160 Human herpesvirus 2 s...
6Q1F_6  81 KPMTGQQ----YAIKNT-GP--FPWEKGDTLTLIPPL--STHsEEKLLKLGDWELTVPLVVPTAIAAEINIRLLCIGL-I 150 Human herpesvirus 6 s...
8TEP_U  85 VPTHGLL----YTVLNT-GP--VTWEKGDALCVLPPLFhGPLaRENLLTLGQWELVLPWIVPMPLALEINQRLLIMGL-F 156 Human herpesvirus 5 s...

6PPB_6 159 SKISAGAPGDVNMAELdlytTNVSFMGRTYRLDVDNTDPRTALR----------VLDDLSMYL--------CILSALVPR 220 Human herpesvirus 8 s...
F5HGN8 159 SKISAGAPDDVNMAELdlytTNVSFMGRTYRLDVDNTDPRTALR----------VLDDLSMYL--------CILSALVPR 220 Human herpesvirus 8 s...
Q01008 159 SRLVESDP-EINIEEVnmytTNVTHMGRHYVLDINHNNPNEALK----------SLDDLAVYT--------CILSALIPR 219 Herpesvirus saimiri (...
Q9QJ27 151 AVHREYN----EMQTIidelCSIQYRDVLIKLP-DIVNDKQSMY----------SMKTACISL--------SMITAMAPD 207 Human herpesvirus 6 s...
F5HIN9 157 SLDRSYE----EVKAAvqqlQTITFRDATFTIP-DPVIDQHLLI----------DMKTACLSM--------SMVANLASE 213 Human herpesvirus 5 s...
Q6UDI3 161 EFCARNQIPADRPAEV-------------YRVACDNKALDLTQAirggdsdlqdTMKTLFASVlfamnegvLQVMTLMPA 227 Psittacid herpesvirus...
Q9E6P9 161 EAIGRGQMPPPTSRES----ETIMYNGRSYTISPTLHSLDAAES----------TVRTLLLNMifainegnMILYTMIPT 226 Marek's disease herpe...
P89441 161 ----RDLNPDPRTPGElpdlNVLYYNGARLSLVADVQQLASVNT----------ELRSLVLNMvysitegtTLILTLIPR 226 Human herpesvirus 2 s...
6Q1F_6 151 AVHREYN----EMQTIidelCSIQYRDVLIKLP-DIVNDKQSMY----------SMKTACISL--------SMITAMAPD 207 Human herpesvirus 6 s...
8TEP_U 157 SLDRSYE----EVKAAvqqlQTITFRDATFTIP-DPVIDQHLLI----------DMKTACLSM--------SMVANLASE 213 Human herpesvirus 5 s...

6PPB_6 221 GCLR-----LLTALVR--------------------HD---RHPLTEVFEGVvpdevtridld---------qlsvpddi 263 Human herpesvirus 8 s...
F5HGN8 221 GCLR-----LLTALVR--------------------HD---RHPLTEVFEGVvpdevtridld---------qlsvpddi 263 Human herpesvirus 8 s...
Q01008 220 ACLR-----VLTILMR--------------------HD---QHELLDVFRGIvprevyeidan---------alsigddi 262 Herpesvirus saimiri (...
Q9QJ27 208 IVRT-----YIDRLTL--------------------ED---HSMLLIKCQELlskrttlstqrcgq----lhatdikdel 255 Human herpesvirus 6 s...
F5HIN9 214 LTMT-----YVRKLAL--------------------ED---SSMLLVKCQELlmrldrersvgeprtparpqhvspddei 265 Human herpesvirus 5 s...
Q6UDI3 228 LLAGgntnpFLNALLQmqsatrlsaq-ifnpptlpvHDptgGARRYNVFDAF---------------------------- 278 Psittacid herpesvirus...
Q9E6P9 227 LLTLgasdgYINALVGletatravgqliripnppplQD---AWRRYPVYEAL---------------------------- 275 Marek's disease herpe...
P89441 227 LLALsaqdgYVNALLQmqsvtreaaqlihpeapmlmQD---GERRLPLYEAL---------------------------- 275 Human herpesvirus 2 s...
6Q1F_6 208 IVRT-----YIDRLTL--------------------ED---HSMLLIKCQELlskrttlstqrcgq----lhatdikdel 255 Human herpesvirus 6 s...
8TEP_U 214 LTMT-----YVRKLAL--------------------ED---SSMLLVKCQELlmrldrersvgeprtparpqhvspddei 265 Human herpesvirus 5 s...

6PPB_6 264 trmRVMFSYLQSLSSIFNLGPRLHVYAYSAETLAASCW 301 Human herpesvirus 8 strain GK18
F5HGN8 264 trmRVMFSYLQSLSSIFNLGPRLHVYAYSAETLAASCW 301 Human herpesvirus 8 strain GK18
Q01008 263 trmTTFITYLQSLSSIFNLGAKLHLSSYASETQTATCW 300 Herpesvirus saimiri (strain 11)
Q9QJ27 256 kkiKSVLTMIDQINSLTNEKTYFVVCDVSADNRMATCI 293 Human herpesvirus 6 strain Z29
F5HIN9 266 arlSALFVMLRQLDDLIREQVVFTVCDVSPDNKSATCI 303 Human herpesvirus 5 strain Merlin
Q6UDI3 279 ---ASWLTMSHRLGELFHMKPALKVVMFYSDVSAIDEG 313 Psittacid herpesvirus 1 Amazon parrot/1997
Q9E6P9 276 ---SAWITMTLNLGNVLSLHPLLKVCTFDGPANIKAGD 310 Marek's disease herpesvirus type 1 strain MD5
P89441 276 ---VAWLAHAGQLGDILALAPAVRVCTFDGAAVVQSGD 310 Human herpesvirus 2 strain HG52
6Q1F_6 256 kkiKSVLTMIDQINSLTNEKTYFVVCDVSADNRMATCI 293 Human herpesvirus 6 strain Z29
8TEP_U 266 arlSALFVMLRQLDDLIREQVVFTVCDVSPDNKSATCI 303 Human herpesvirus 5 strain AD169
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