7M30


Conserved Protein Domain Family
Cytomega_gL
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pfam01801: Cytomega_gL (This model is not part of the current CDD release)
Cytomegalovirus glycoprotein L
Glycoprotein L from cytomegalovirus serves a chaperone for the correct folding and surface expression of glycoprotein H (gH). Glycoprotein L is a member of the heterotrimeric gCIII complex of glycoprotein which also includes gH and gO and has an essential role in viral fusion.
Links
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Statistics
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PSSM-Id: 514514
Aligned: 4 rows
Threshold Bit Score: 289.875
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7M30_B  15 A-ECPELTRRCLLGEVFQgdkyeswlrPLVNvtrrDGPL-------SQL--IRYRPVTPEAANS-VLLDDAFLDTLALLY 83  Human betaherpesvirus 5
F5HCH8  45 A-ECPELTRRCLLGEVFEgdkyeswlrPLVNvtgrDGPL-------SQL--IRYRPVTPEAANS-VLLDEAFLDTLALLY 113 Human herpesvirus 5 s...
P52508  33 D-DCIAAVINCTKSEV-----------PLL-----LEPIyqppaynEDVmsILLQPPTKKKPFSrIMVTDEFLSDFLLLQ 95  Human herpesvirus 6 (...
P52514  52 EhKCREALASCYNGSEFQ---------PLHD----DGPIrpdpyrfSTM--IRFKRSYGELPLP-IELNDEFLEQLSLLH 115 Murine cytomegaloviru...

7M30_B  84 NNPDQLRALLTLLSSDTAPR-WMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVPPSlFNV- 161 Human betaherpesvirus 5
F5HCH8 114 NNPDQLRALLTLLSSDTAPR-WMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVPPSlFNV- 191 Human herpesvirus 5 s...
P52508  96 DNPEQLRTLFALIRDPESRDnWLNFFNGFQTC-SPSVGITTCIRDNCRKYSPEKITYVNNFFVDNIAGLE------FNIs 168 Human herpesvirus 6 (...
P52514 116 NNTDQLRVLLTLMRTSRASD-WMSFLGGYTQCDAPKSVVFTCVESVCYEHDLMRLNYTTDLFTENVLGLDVSPPV-LSV- 192 Murine cytomegaloviru...

7M30_B 162 ------------VVAIRNEATRTNRAVRLPVSTaaapegITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELK- 228 Human betaherpesvirus 5
F5HCH8 192 ------------VVAIRNEATRTNRAVRLPVSTaaapegITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELK- 258 Human herpesvirus 5 s...
P52508 169 entdsfysnigfLLYLENPAKGVTKIIRFPFNS------LTLFDTILNCLKYFHLKTGVELDLLKHMETYNSKLP--FR- 239 Human herpesvirus 6 (...
P52514 193 ------------LVLLRNNHTKAESVVRVPTSS------MSLLDGTYNLLRTILGHMSLDTDLIGVLRSYRDRFPAVFSv 254 Murine cytomegaloviru...

7M30_B 229 QTRVNLPAHS 238 Human betaherpesvirus 5
F5HCH8 259 QTRVNLPAHS 268 Human herpesvirus 5 strain Merlin
P52508 240 SSRPTILIRN 249 Human herpesvirus 6 (strain Uganda-1102)
P52514 255 SDQIKITRQH 264 Murine cytomegalovirus (strain Smith)
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