1JEE,2GKS,1V47,4MAF,3CR8


Conserved Protein Domain Family
ATP-sulfurylase
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pfam01747: ATP-sulfurylase (This model is not part of the current CDD release)
ATP-sulfurylase
This domain is the catalytic domain of ATP-sulfurylase or sulfate adenylyltransferase EC:2.7.7.4 some of which are part of a bifunctional polypeptide chain associated with adenosyl phosphosulphate (APS) kinase pfam01583. Both enzymes are required for PAPS (phosphoadenosine-phosphosulfate) synthesis from inorganic sulphate. ATP sulfurylase catalyzes the synthesis of adenosine-phosphosulfate APS from ATP and inorganic sulphate.
Links
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Statistics
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PSSM-Id: 514470
Aligned: 148 rows
Threshold Bit Score: 63.3631
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1JEE_A       169 PGLRKTPAQLRLEFqsRQWD-R----VVAFQT-RNPMHRAHRELTVRAAR--EANAk------VLIHPVVGLTKPGDIDH 234 brewer's yeast
WP_012174441 172 RQLRKSPAEVRELYrkLSWH-R----VIGFHT-RQPVHRLQFEMTIRAMRtaRAN--------LLCLPSVGTIDPDDVDH 237 Desulfosudis ol...
WP_014956369 165 KQIRNTPAEVQKTFakLGWK-R----IVGFQT-RQPIHRPQFEMTIQAMQkaRAN--------LLLLPIAGVTKPGDFDH 230 Desulfobacula t...
WP_004071574 166 KQIRNTPSEVRQQFckLGWK-R----IVGFQT-RQPIHRPQFELTIQAMKkaKAN--------LLMLPIAGIPRPGDFDH 231 Desulfobacter p...
WP_354891770 132 RELRVTPAEVRa---qRELDpTahqpLLAVVT-DRPLH--HRALHQIRAEadALGRdggraevLVII---------DAPL 196 Nocardiopsis alba
Q0P819       130 sqiekikENFQQIKnnLNAQ-K----ITAIVSsFDPLHRAHERMFRWTID--KAD--------LVVIFLVESFDVNGFEF 194 Campylobacter j...
WP_013554602 141 plIRDTVNRIRQMIrrTGAQ-K----ISAMMLaANPLNRAHERIIRQILT--RAD--------LVVLFLRKPFTDEGLRY 205 Nitratifractor ...
WP_012081970 141 EDVKKAKEEIAKRKkeLKAK-E----VSAIMLaAKPLHRAHERLIRSTLE--HSD--------LVVLFLLKPYVNDQFSY 205 Nitratiruptor s...
WP_012857474 142 ddikqiKTNIQEAKkeLDAK-N----VAAIMInANPFHRAHERVIRMTLE--KYD--------LLVIFLLKPYKQDILSY 206 Sulfurospirillu...
Q7M820       141 eDVKEVKRKIKEAQeaIGAK-H----TAALMLsAKPLHRGHERIIRLTLD--ETD--------LLVLFLLKPYRTDIMDY 205 Wolinella succi...

1JEE_A       235 HTRVRVYQEIIKR-Y-PNG-IAFLSLLPLAMRM-SGD-------REAVWHAIIRKNYGASHFIV---GRDHAGPGknskg 300 brewer's yeast
WP_012174441 238 YTRVRCYKRVAERy--PPD-SFLLNLVPMAMRM-AGP-------REALLHLIVARNFGCSGFII---GPDHASPP----- 298 Desulfosudis ol...
WP_014956369 231 FTRMRCYQKVAAHy--PPD-TYVLNLLPLAMRM-AGP-------REAILHMIIGKNFGCTHFVI---GHDHASPG----- 291 Desulfobacula t...
WP_004071574 232 YTRMRCYQKVAAYy--PPD-TYMLNLLPLSTRL-AGP-------RDAVLHMIIGKNFGCTHFVI---GHNHATPG----- 292 Desulfobacter p...
WP_354891770 197 EDEGAASAVLAAEpLlPPRsVFVVATLPRSSRRgSGPfggewteRDAALAAHVAAAYGATHMLLetgGRGPE-------- 268 Nocardiopsis alba
Q0P819       195 ELKEAYLKKFIQN-YlPPD-RIFIFPLKNINIF-HAH-------LNPGLESIIAKSLGCTKLVV---GQNHTGLG----- 256 Campylobacter j...
WP_013554602 206 DIRHNAVQLFIDN-FlPRN-KVLVVPFENTYIF-AGY-------NELVLDALLARNAGCNELVI---GKNHAGLG----- 267 Nitratifractor ...
WP_012081970 206 ELRYKTVDYFVKN-YlPKN-RVITVPLENTYIF-AGF-------NELILDAIVAQNFGCTRLVV---GKNHAGLG----- 267 Nitratiruptor s...
WP_012857474 207 DLRLKSLQYFVDN-YlPKN-RVVIVPFENTYLF-SSY-------KNAILDSICASNYGCNKLIL---GQHHSGIG----- 268 Sulfurospirillu...
Q7M820       206 SLRHKTLEYLVEN-YlPKS-RVLIVPLEDTYLF-AGG-------NEMILDAIVAQNLGCDKLVT---GANHAGLS----- 267 Wolinella succi...

1JEE_A       301 vD------FYGPYDAQELVE-SYKHELDIEVVPFRMVTYLPDED------RYAPidqidTTKTRTLNISGTELRRRLRVG 367 brewer's yeast
WP_012174441 299 -HpdngvaFYEKDRACRLLE-THAGELGMEVIVFNEIVYLPFEDefvpvdQV-------ADGTQYVSMPGSLIRRRMRAG 369 Desulfosudis ol...
WP_014956369 292 -NdsgntpFYKYDEAIELTR-EITRELNVETVTFKEMVYLPFEDeykiagQV-------PKNTDTISFNGTDIQKRIRNG 362 Desulfobacula t...
WP_004071574 293 -SdscgnpFYDTPQVRALAE-QAGEEIGIEPVFFEEMVYLPFEDefklasEV-------TDGQETLSFTNDHIRDRVRKG 363 Desulfobacter p...
WP_354891770 269 --------------IERVMAlR----PPLTVLDPEPWRYDSGEElwkp-------ftgvDPRRARREPSDGEVENELAHG 323 Nocardiopsis alba
Q0P819       257 -M------FYDDNQPKTILD-DFSKDYGIEVIVLPEFVFCDQCR------MIVStrscpHGCHHHLHYNSQSLKDLLRAG 322 Campylobacter j...
WP_013554602 268 -L------YYDQNRLNTIFD-TLSG-LDLEITTVDEYVYCDTCR------TLVStetcpHGQHHHIHYHSESIMTLIQNG 332 Nitratifractor ...
WP_012081970 268 -L------YYDKNSLKSVFD-NLKG-INIQIEMVNEFVYCDKCK------TLVStetcpHGSHHHISYHADSILELLKLG 332 Nitratiruptor s...
WP_012857474 269 -A------YYDKNEMKSVVN-QYND-LDIEIEIIAEFVYCDECK------TLVStstcpHGAHHHIKYHAKSLLEILKLG 333 Sulfurospirillu...
Q7M820       268 -M------YYDRNQMRSIFD-TLKG-IDIDIKIMSEFVYCNMCR------TLVStktcpHGHHHHITYHSDSIFEFFRLG 332 Wolinella succi...

1JEE_A       368 GEIPEWFSYPEVVKILRES 386 brewer's yeast
WP_012174441 370 KTVPDWATFPEVLEELERa 388 Desulfosudis oleivorans
WP_014956369 363 KRVPDWATFPEVIQELQKS 381 Desulfobacula toluolica
WP_004071574 364 KHIPEWASFPDVIKELRRS 382 Desulfobacter postgatei
WP_354891770 324 RELPSWFTPARVGAELARl 342 Nocardiopsis alba
Q0P819       323 IIPPAIFIRKEVSSVILTs 341 Campylobacter jejuni
WP_013554602 333 ILPPPILVRKEISANILas 351 Nitratifractor salsuginis
WP_012081970 333 LLPPAVLVRKEISAILLSE 351 Nitratiruptor sp. SB155-2
WP_012857474 334 MLPPAIFMRKDISAMLLSE 352 Sulfurospirillum deleyianum
Q7M820       333 LLPPAVLVRKEISAIILSE 351 Wolinella succinogenes
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