1LFP,1MW7,4F3Q


Conserved Protein Domain Family
Transcrip_reg

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pfam01709: Transcrip_reg 
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Transcriptional regulator
This is a family of transcriptional regulators. In mammals, it activates the transcription of mitochondrially-encoded COX1. In bacteria, it negatively regulates the quorum-sensing response regulator by binding to its promoter region.
Statistics
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PSSM-Id: 460302
Aligned: 695 rows
Threshold Bit Score: 118.304
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1LFP_A                5 SHWAQIKHKKAKVDAQRGKLFSKLIREIIVATRlGGpnpefNPRLRTAIEQAKKANXPWENIERAIKKGAGeL-EGe-QF 82  Aquifex ...
WGS:ABKH:PAAG_04610  38 SRWSTIKHDKGKNDAAKSKERVLYARDIINASKlFGpdpslNPRLALVIAKAKRSGMSKSTIEAAIARGQG-VsSTgaAL 116
XP_002847623         38 NRWSTIRHDKGKNDAAKSKERQIFSKDIIQASKlYGpdpksNPRLALVIANAKRSGMPKPTIEAAIARGQG-ItAAgaAL 116
XP_016764071         41 SRWSKIQHDKAKVDMRKNKQRSIFAAQIALASKlNGpdpntNPHLFDLIAQAKREGFAKASIEAAIARGQG-RsLSgaNL 119
EME47538              7 SRWSKIKHEKAKVDAGKNKQRSIFAQELATASRlFGgdpnmNPRLADLVTKAKKEGFAKASIEAAIARGQG-RsVSgaSL 85 
XP_003849092         58 SRWSKIKHDKAKVDASKNRQRSIFAHEIATASKlFGgdpgsNPRLADLITKAKREGFAKASIEAAIARGQG-RsTTgaSL 136
XP_007676450         52 NRWSKIKHDKLKTDAAKNRARSIFAQEIATASKlFGpepnsNARLADLITKAKREGFAKTSIEAAIARGQG-RsTSgaSL 130
XP_007776878         40 SKWATIKHDKGKNDAAKNKQRSVFSHEIANASKfYGpdpntNARLALAISLAKKAGVPKANIESAIARGQG-VsASgaAL 118
EMD59402             51 SKWATIKHDKAKNDAGKSKQRSLMTRDITNAVKlAGpnpdmNPRLALAIATAKKSAVPKASIEAAIARGQG-LsAAgtAL 129
Q0V2T5               48 SKWASIKHDKAKNDAARSKQRVLLTRDITVAVKlSGpdpnmNPRLALALTTAKKSAVPKTAIEAAIARGQG-LsTTgaAL 126 Parastag...
1LFP_A               83 EEVIYEGYAPGGVAVXVLATTDNRNRTTSEVRHVFTKHGGNLgasGCVSYLFERKGYIEVPAKeVSE-EELLEKAIEV-- 159 Aquifex ...
WGS:ABKH:PAAG_04610 117 ESVTIEALLPGSVAVVIECMTDQKARTLQDLRFLIKHHGGTV---TPTSYLFEKKGRIVFEKVeGLNvDDYLEQAIDA-- 191
XP_002847623        117 ESLTIEGMLPHSVAVVVECLTDQKARALQDIRAIIRHSGGSN---TPTSYLFEKKGKIVFEPKpGLDvDSYLELAIDA-- 191
XP_016764071        120 ETVTVEGILPNNVAVIVECETESKLRTLAEVRLAIKSNGGSA---TPTSYLFTKKGVVTFQKKdGVGvDEAFEVALEA-- 194
EME47538             86 ENITVEGILPNNVAIIVECETDSKLRTLAEVKLAIKEAGGSA---TPTGYLFAKKGRIVFEAKdDIGmDEMLEPALDA-- 160
XP_003849092        137 ESVSVEGILPNNIAIIVECETDSKLRTLADVRLAIKDHGGST---TPTSYLFAKRGKITFESKeGIGqDEILEPALEA-- 211
XP_007676450        131 ESVTVEGILRNNVGVIVECETDSKLRTLADVRLIMKENGGSA---TPCSYLFRKKGRIVFEAKeGVGvEEALDAALEA-- 205
XP_007776878        119 EPVTVEAIFPPSVAVVIDCLTDNKLRILADIRHLIKQHQGSV---TPTNYLFEKKGQIIFKPKeGLGaDEVLDTALEAap 195
EMD59402            130 ESLVLEAILPPSIATIIECQTDNKLRALADLRLLVKEAGGTV---STVAFMFEKKGRIILRKKdGVTvDEVLEPALEA-- 204
Q0V2T5              127 ESLVLEAILPPSVATIIECQTDNKLRALADLRLLVKEAGGQV---STVGFMFEKKGRIIMRKKeGIGmDEVLEPALDA-- 201 Parastag...
1LFP_A              160 GAEDVQp----GeevHIIYTVPEELYEVKENL-EKLgvP-IEKAQITWKPISTVQIn-D-EETAQKVIKLLNALEEL-DD 230 Aquifex ...
WGS:ABKH:PAAG_04610 192 GAIDVDtddqgR---LRVFTEHTDTKAVGDKLsVTTg-LkIETSDIIWDPYRDTIVklEsEEDAHKIEEILNAIRED-SS 266
XP_002847623        192 GATDVEgdennR---LIVYTEHTATKSVADKMsATTd-LvTESIDIIWDPNQDTLVkiEsEEALSTVENIINSLRDD-PS 266
XP_016764071        195 GATDVDsdpdgR---IVVSTEPSDLSAVGDTIaRALd-LqIVSSEVIWDPNEDTKVeiPsEEAAGELSDFVDELLQKeQS 270
EME47538            161 GAQDVTkdgdgR---VVVWTEPADTKAVGEAIsKDLn-VqIATSNIVWDPNEDTKVvvPgEEIAGELSHFIDQLQEKeTS 236
XP_003849092        212 GALDVAeddgkR---VVVFAEPTETRAVGDAIsKALd-VqIATSDIIWEANEDTKVdiAsEQAADDIHAFLDKLEEKeAS 287
XP_007676450        206 GAMDVEddgegR---IVVSTEPEDTKSVGEAVaNALs-LqIATSEILWEPNEETKVgvPdEQSAQELSAFLDDLEEReAS 281
XP_007776878        196 GVLDVVegadgR---VVVFTEPADTKGTGETLsGALg-LeVEESEIIWDPNEDTKVeiSdEEAAQALSGFAEKLQDI-SG 270
EMD59402            205 GVLDVDedaegR---VVLYTEPAMTNKTAEKLsKDVg-LeIEESEIIYDPNEDTKVtlDdEGAAKELSNFLDELQEV-QG 279
Q0V2T5              202 GVQDVHedeegR---VLLFTEPAQTKTIAESLaKELd-MeIEESEIIYDPNEDTKVevNdEEAAAKLSNFLDDLQEV-QG 276 Parastag...
1LFP_A              231 VQQVIANF 238 Aquifex aeolicus
WGS:ABKH:PAAG_04610 267 VQDIYTNS 274
XP_002847623        267 VQDIYVNc 274
XP_016764071        271 VQSISLNV 278
EME47538            237 VQSVAMNI 244
XP_003849092        288 LQSVAMNV 295
XP_007676450        282 LQAVAMNV 289
XP_007776878        271 VQAMYMNA 278
EMD59402            280 VQGVYMNW 287
Q0V2T5              277 IQGVYMNW 284 Parastagonospora nodorum SN15
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