3BIC_A          52 HTPEGISI----KPLYSKRDT---MDlPEe------LPGVKPFTRGPYPTmYTFRPWTIRQYAGFSTVEESNKFYKDNIK 118  human
WP_013611774    41 RTNEGFNV----QPMYRLENM-------QdlknldcLPGEFPFVRGNK---KDNNDWYVRQDIVVEDLAEANKKALDVLN 106  Odoribacter ...
16_pfamImport    1 RTNEGFDV----QPMYRLENM-------KdlknldcFPGEFPFVRGNK---KDNNDWYVRQDIKVDNIVEANKKALDVLN 66  
15_pfamImport    1 RTNEGFSA----EPFYRKEDL-------EgmaqtdaLPGEFPYLRGNK---KDNNRWYVRQNIRVTDPKEANEKALDLLN 66  
9_pfamImport     1 RTNEGFNV----QPFYRREDL-------AnlktpdaLPGEFPFVRGNK---KDSNEWYVRQNIEAADPKAANAKALDILN 66  
CCX67544        40 RTNEGFDV----PPFYRREDV-------LklntpdsLPGEFPYVRGNK---KSCNCWYVRQDIMADDAKAANAKALDVIG 105 
WP_022317285    40 RTNEGFNV----QPFYLKEDL-------EnlktpdsLPGEFPFVRGNK---KGDNAWYVRQRIMADDAAAANEKALDILN 105  Prevotella
WP_012499402    44 QTLEGFNI----QPFYTAEDT-------NgldylqtPPGEFPYVRSAK---QQGNDWQIREDVEISDIGDAARQIAEALA 109  Chloroherpet...
Q8EXE0          38 ETAEGFKI----QPVYTKEDIgdkQWlt------snLPGTFPFARSTR---KLVSDWSIRQDLDSNSISEANQLAKEAAS 104  Leptospira i...
Q0KEZ0         547 tTLSGTKVrkvvLPRFEDDGE------VLkwlmrenVPGSFPYTAGVFAF-KRENEDPTRMFAGEGDAFRTNRRFK-LVS 618  Cupriavidus ...

3BIC_A         119 AGQQG--LSVAFDLATHRGYDSDNPRVRG-DVGMAGVAIDTVEDTKILFDGIPLEK--MSVSM-TMNGAVIPVLANFIVT 192  human
WP_013611774   107 RGVNS--LGFVLNGCQ----------------------EFTKADMEVLLKDICLEC--VEINF-VAGCKKGSILDAFKAV 159  Odoribacter ...
16_pfamImport   67 RGVNS--LGFIFTGCR----------------------EFSKADMEALLKDICLEC--VEINF-VCECKKCSVVDAFKAV 119 
15_pfamImport   67 KGVTS--LGFKVPAK-----------------------ELNATFISTLLEGIKADA--VELNFsTCQGHTVELARLLTAY 119 
9_pfamImport    67 KGIDS--LGFHIPGK-----------------------LVSMDTIETLLDGIYCEC--VEVNFsTCQRHSLELAEILKTY 119 
CCX67544       106 RGVDS--VGFRIPGD-----------------------SVSAGFVETLLAGIDCEA--VEVNFnTCKRHTLELAQILAAY 158 
WP_022317285   106 RGVDS--LSFKIPGK-----------------------NISKDFVETLLKGIECEA--VELNFnTCKRHTLELAKILDWY 158  Prevotella
WP_012499402   110 KDAAA--VGLLFKQPM----------------------ALTQSDFSRLIEAVDFEK--HNIHL-LAEKDSPLLFELLTAE 162  Chloroherpet...
Q8EXE0         105 NGVTA--IGFIIENKT--------------SP-QKGIPVNSSKDLETLIQGLPFDQ--VTLHF-IAEERSPEIFSWLP-- 162  Leptospira i...
Q0KEZ0         619 EGMDAkrLSTAFDSVTLYGEDPHVRPDIYgKVGNSGVSIATLDDMKVLYDGFDLTSpsTSVSM-TINGPAPTILAMFMNT 697  Cupriavidus ...

3BIC_A         193 GEEQGVP----------------------KEKLTGTIQNDILKEFMVRNTY-IFPPEPSMKIIADIFEY-TAKHMPKFNS 248  human
WP_013611774   160 VEERGIA----------------------PEKIQGGINVDPLTALTRKGKNcC---DKPFENVKVNLEK-MAA-YKNFKT 212  Odoribacter ...
16_pfamImport  120 VAERGIA----------------------PEKIHGGINIDPLTNLTLKGKIcC---ENPFGAPKENTEK-MLD-FKNFKT 172 
15_pfamImport  120 YDGKGYD----------------------RTALVGSIDFDPMQKILTKGKDt----TALLNKLAELVNI-LAP-FPKMRC 171 
9_pfamImport   120 WTKKGYD----------------------KEKIVGSIEWDPMKKIVMTGKDv----TPVLAFGPKLAES-LKE-YPNFRS 171 
CCX67544       159 FDKKGYD----------------------KAKVNGSLDWDPMEKIVMKGHDv----TPILELAPQIIEA-LKD-YPRFRC 210 
WP_022317285   159 FTAKGYD----------------------KTKIVGSFNWDPMEKIVVKGLDt----VALLAQAPQIVEA-MKE-YPNFRT 210  Prevotella
WP_012499402   163 AASRSAS----------------------FQSLKGSLGYDPLGSFALTGRFaQDEKSAML-TAAKLIGA-LKE-NPNFKA 217  Chloroherpet...
Q8EXE0         163 ------K----------------------DKVLVGGLGYDPFRILLKHGRSgK----HSIPVLKEILET-FASSWPHYRG 209  Leptospira i...
Q0KEZ0         698 AIDQQLDkfradnqreptadeeakirawvLQNVRGTVQADILKEDQGQNTC-IFSTEFSLKVMGDIQEYfVHHQVRNFYS 776  Cupriavidus ...

3BIC_A         249 ISISGYHMQEAGADAILELAYTLADGLEYSRTGL-QAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEkMF 327  human
WP_013611774   213 IEVGGYVFNNSGSSIVQELGFSLAAGVEYLDKLT-DAGMKIDEVAPKIRFHFATGSKYFMEIAKLRAARYLWAHIVKaY- 290  Odoribacter ...
16_pfamImport  173 IEVGGYVFNNSGASIVQELGFSLAAGVEYLDKLT-DAGMSINDVAPHIRFHFATGSKYFMEIAKLRAARYLWAHIVKaY- 250 
15_pfamImport  172 ICINADTLCNAGAYIYQELGYALAWGNEYLNLMV-EAGIPAALAAKKIKFNFGISGVYFMEIAKFRAARMMWAQIVKqY- 249 
9_pfamImport   172 IIVHSDALNNAGAYIVQELGYALAWGNEYLQQLT-DAGVDVDLAAKSIKFNMGVSENYFMEIAKFRAARLLWAQIVKqY- 249 
CCX67544       211 ITVNAVALNNAGAYIVQELGYAMAWGNEYMEILT-EAGVDVDLAASKITFNMGISENFFMEIAKFRAARLLWAEIVKkY- 288 
WP_022317285   211 ICVNAVALNNNGAYIVQELGYALAWGNEYMNQLV-EAGTDADEAAKNIKFNLGISENFFMEMAKFRAARMLWAEIVKqY- 288  Prevotella
WP_012499402   218 ITVSGEVYHESGATTVQELAFTLAAGNEYLAKLT-ELGLSADEVLSHIQFTFAIGSSYFKEIAKLRAARLLWAQLAEaY- 295  Chloroherpet...
Q8EXE0         210 LSVYSSTFRDAGSTISEELAFTLAAAAEYVQQLKtA-GMDVDTIASQLMFEFSIGPDYFLEIAKFRSARILWAEILKeF- 287  Leptospira i...
Q0KEZ0         777 VSISGYHIAEAGANPISQLAFTLSNGFTYVEAYL-ARGMHIDDFAPNLSFFFSNGMDPEYSVLG-RVARRIWAVTMRdKY 854  Cupriavidus ...

3BIC_A         328 QPKNS--------------KSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALG-LPTVKSA 392  human
WP_013611774   291 NPSCD--------------CKCKMNIHAETSEWNKTVYDPNVNMLRTQTETMSAVLGGVDSFTVHPFDDTFEcHPSDVAE 356  Odoribacter ...
16_pfamImport  251 NPSCD--------------CVCKMNIHSETSEWNKTVYDPNVNMLRTQTEAMSAILGGVDSYLVHPYDYIYEcEPSELGE 316 
15_pfamImport  250 NPVCPredctntgedkscnCACKMYVNATTSTYNMTVFDSYVNMLRTQTEAMSAALANVDAIVVTPFDAPYE-VPTDFAE 328 
9_pfamImport   250 EPKCD--------------CACKMIINATTSTYNQTLFDSYVNLLRSQTEAMSAALGSVHSMVVTPFDAPYE-EATDFSE 314 
CCX67544       289 EPKAD--------------ASCMMCVNAITSKYNMTLFDSYVNLLRSQTESMSAALAGVHSIVVTPFDAVYE-TPNDFSE 353 
WP_022317285   289 APKDD--------------ASCMMCVNAATSKYNMTMFDSYVNMLRSQTEAMSAALAGVHSIEVLPFDAVYE-TPNEFSE 353  Prevotella
WP_012499402   296 APAAK--------------ESAKMKIHAVTSAWNMTIYDPHVNMLRATTEAMSAAIGGCDSLTVRPFDSIYK-TPDGFSN 360  Chloroherpet...
Q8EXE0         288 SPKVE--------------SSLHAFLSAHTCRYNYSAYDPNVNMLRATTEAMSAAIGGCEVINVSPYDSILK-TSDSFSL 352  Leptospira i...
Q0KEZ0         855 GANER---------------SQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDEAIT-TPTGESV 918  Cupriavidus ...

3BIC_A         393 RIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSG 472  human
WP_013611774   357 RVARNQQLLLKEESHFAKIVDVAGGSYYIEELTQNIAEAAWKLFLETQEQGGYIEALKKGFVQAAVKATAQARNLAIAQR 436  Odoribacter ...
16_pfamImport  317 RVARNQQLLLKEESHFAKIADVPGGSYYIEELTENIAEAAWKLFLQVQEEGGYVEAFKKGFVQAAIKATAQARDLAIAQR 396 
15_pfamImport  329 RIARNQQLLLQEESHFDKIVDVAGGSYFIETLTRSLAEGAWKLFLAVEEEGGFLAAAKAGSIQKAVNDTNAKRHANAGKR 408 
9_pfamImport   315 RIARNQQLLIKEESHFDRIVDPSAGSYYIEHLTDALATEAWKIFLKVEDEGGFLAAVKAGTVQDDINATNVKRHGDAAKR 394 
CCX67544       354 RLARNQQLLLKEESHFDKVVDPAAGSYFVEELTTSLANEGWKIFLNVENNGGFLEAAKKGLVQDDVNATNAKRHEAAAKR 433 
WP_022317285   354 RIARNQQLLLKEESHFDKVVDPGAGSYFIEELTTSLANEAWKIFLNVEDNGGFLEAAKKGIVQDDINATNAKRHDAAAKR 433  Prevotella
WP_012499402   361 RIARNLQHLLKCESYLDKIIDPASGSYYIESLTDSLASAAWKRFQEIEKEGGLSASLRAGTIQKDIAAVQAERNKRIEHR 440  Chloroherpet...
Q8EXE0         353 RIARNIQLLMKHESYIDKVVDPAAGSYYLESLTDSITKKAWEIFCEIESIGGFLEGIQKGIIQKKVADSRKKKEENLANR 432  Leptospira i...
Q0KEZ0         919 RRALAIQLIINREWGVARCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDG 998  Cupriavidus ...

3BIC_A         473 SEVIVGVNKYQ----LEKe----------------------dTVEVLAIDntsvRNRQIEKLKKIKSS------RDQALA 520  human
WP_013611774   437 KENFVGVNQFp----NFNekidrqlcac----ifepedetaeGAEIETLK----PYRGPAAFEAMRLQtda-fsAKNGRP 503  Odoribacter ...
16_pfamImport  397 KENFVGTNQFp----NFNekiekaicsc----vlepedhtaeGAMVETLK----PYRGAQAFEALRLKtdm-yaAKNGRP 463 
15_pfamImport  409 KEFLLGTNQFp----NFNeksegkaplaa--tccchshgdscEKPFAKLE----TSRLAADFEALRLQt----eQAEKQP 474 
9_pfamImport   395 KEFLLGTNQFp----NFTeksenkraykhhcgcggvhhhgeeTVAFKGIE----STRLAADFENLRIHt----eET-KVP 461 
CCX67544       434 KEFILGTNQFp----NFTeksedkrplgc---tcscggghkhEAEFKAIE----TTRLAADYEDLRLKv----eESAKVP 498 
WP_022317285   434 KEFILGTNQFp----NFTeksegkrakna---ccgcadkgahEEAFKAIK----TTRLAADFEDLRISv----eESEKTP 498  Prevotella
WP_012499402   441 RQVFIGVTQYp----NPAervsdslkr-------ldvepetdGAEIAPLK----PVRGAKAFEACRLAtefhaeKHGHRP 505  Chloroherpet...
Q8EXE0         433 KEILLGTNQYp----NGEdrvpelnqnk----tlgeidsvtgETTCERIF----EFRAGADIEEIRLKtetfakKSGKTP 500  Leptospira i...
Q0KEZ0         999 TLPIIGVNTFRnpdgDPTp----------------------qKLELARSS----EAEKQSQLDRLHAFq----qAHAAEA 1048 Cupriavidus ...

3BIC_A         521 ERCLAALTEcAASgdgNILALAVDASRARCTVG-EITDALKKVF 563  human
WP_013611774   504 VVYMFPMGNlAMR-----KARAQFACNFFACAGfEvkdnngfkt 542  Odoribacter splanchnicus
16_pfamImport  464 VVYMFPMGNlAMR-----KARAQFACNFFACAGfQV-------- 494 
15_pfamImport  475 VAFMLTIGNlAMR-----QARAQFSCNFLACAGyKV-------- 505 
9_pfamImport   462 TAFMLTIGNlAMR-----QARAQFSCNFLACAGyKV-------- 492 
CCX67544       499 VAFMLTIGNlAMR-----QARAQFSCNFLACAGyKVvdnlgfkt 537 
WP_022317285   499 TAFMLTIGNlAMR-----QARAQFSCNFLACAGyKVmdnlgfkt 537  Prevotella
WP_012499402   506 KVFLLPIGDlAMR-----IARATFSYNFFGCAGfEilsnngfkt 544  Chloroherpeton thalassium
Q8EXE0         501 TVLLLPMGDlKMK-----KARAIFSQNFLACAGyKVvdpgsytt 539  Leptospira interrogans
Q0KEZ0        1049 PAMLAQLRQaVIDn-qNVFAVLMDAVRV-CSLG-QITHALFEVG 1089 Cupriavidus necator H16