5HPI,1TF1,1TD5,1YSP,1YSQ


Conserved Protein Domain Family
IclR

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pfam01614: IclR 
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Bacterial transcriptional regulator
This family of bacterial transcriptional regulators includes the glycerol operon regulatory protein and acetate operon repressor both of which are members of the iclR family. These proteins have a Helix-Turn-Helix motif at the N-terminus. However this family covers the C-terminal region that may bind to the regulatory substrate (unpublished observation, Bateman A.).
Statistics
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PSSM-Id: 426346
Aligned: 18 rows
Threshold Bit Score: 72.7003
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5HPI_D  49 RVSPYGxhLGNRLPAHATSTGKVLLSVLd-REVQIEWIEKy--GLKRLTPYTITDEHTFLETLDAVRQSDYCLSTEEHEL 125 Acinetobacter baylyi ...
Q6FDI1 138 gpfTSTisLGTRWPAHATVIGQLLLSNLseTEIRQRYRKFd--EWDTFSELTPKNLKELLLRLNYVKTQPSMVSWGHYNN 215 Acinetobacter baylyi
Q88N41 160 rlISVDlsVGGRLPAYCTSMGRILLAAMd-DTSLREYLERa--DLKARTSRTLNDPESLFACIQQVRAQGWCVVDQELEQ 236 Pseudomonas putida KT...
P44996 134 LKTRAY--IGQYLKLYCSAMGKIFLAYEkkVDYLSHYWQShqrEIKKLTRYTITELDDIKLELETIRQTAYAMDREENEL 211 Haemophilus influenza...
O83046 149 RVNPYGlhLGNRLPAHATSAGKILLAYLd-DHAQQEWLNQy--PLQRLTKYTYTNNIDFLRLLSEIKEQGWCYSSEEHEL 225 Acinetobacter baylyi ...
O06806 130 YRLRAVsaVGLRFPLNGTANGKAALAALd-DADAEAALCR--------LDPMVA--EGLRREIVEIRRTGIAFDRNEHTP 198 Mycobacterium tubercu...
P71977 127 QRLRAVsaVGESFPLYCCANGKALLAALppERQARALPSR----LAPLTANTITDRAALRDELNRIRVDGVAYDREEQTE 202 Mycobacterium tubercu...
P77732 121 ATISVRshEGKSLSLYRSGIGKCLLAWQp-AAVQQSIIEGl--VWEQATPTTITHPQQLHEELARIRRQGWSYDNGEDYA 197 Escherichia coli K-12
P39360 121 SVPTSKswIGKKLELHITALGKALLAWKt-REELDYFLEAl--TLTPHTRNTFTDKKLFLEELQKTRLRGWAIDNEESTY 197 Escherichia coli K-12
1YSQ_A  52 LRTRAY--IGQHMPLYCSAMGKIYMAFGh-PDYVKSYWEShqhEIQPLTRNTITELPAMFDELAHIRESGAAMDREENEL 128 Escherichia coli
5HPI_D 126 GVIAIAVPVLNA-QGLTIAALNCXSQTNRVQPQYLIDq--VLPLLRNTANELRNL 177 Acinetobacter baylyi ADP1
Q6FDI1 216 DMAACAAPIYRQsSKDMVAVLSVSCPITTYDEYTFKHs--VAAQVIETADKISKf 268 Acinetobacter baylyi
Q88N41 237 GLRSIAVPVYDA-SGQVLAALNVSTHVGRVTRSELEQr--FLPILLAASRDLCHq 288 Pseudomonas putida KT2440
P44996 212 GVTCIACPIFDS-FGQVEYAISVSMSIYRLNKFGTDA---FLQEIRKTAEQISLE 262 Haemophilus influenzae Rd KW20
O83046 226 GVHALAVPIYGQ-QSRVVAALNIVSPTMRTTKEYLIQh--ILPLLQETARELRNI 277 Acinetobacter baylyi ADP1
O06806 199 GIS-AAAIARRA-LGDNVIAISVPAPTARFLEKEQRI----IAALRAAADSPDWT 247 Mycobacterium tuberculosis
P71977 203 GICAVGAVLRG--VSVELVAVSVPVPAQRFYGREAELagaLLAWVSKVDAWFNGT 255 Mycobacterium tuberculosis H37Rv
P77732 198 DVRCVAAPVFNA-NNELTAAISVVGTRLQINEEYRDY---LAGKAIACARDISRL 248 Escherichia coli K-12
P39360 198 GAVCLSMPVFNM-YNRVNYAISLSGDPVVYSGNKIDS---YLELLRKCAEQISYG 248 Escherichia coli K-12
1YSQ_A 129 GVSCIAVPVFDI-HGRVPYAVSISLSTSRLKQVGEKN---LLKPLRETAQAISNE 179 Escherichia coli
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