Conserved Protein Domain Family

pfam01599: Ribosomal_S27 
Ribosomal protein S27a
This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesized as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilisation and is required for efficient ribosome biogenesis. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins.
PSSM-Id: 426338
Aligned: 59 rows
Threshold Bit Score: 44.1019
Created: 26-Apr-2021
Updated: 29-Sep-2021
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
5OPT_j                98 LKYFKVtenDDgSFKVERTRDECPNpvCGAGVFMAQHKD---RKYCGKCHLT 146 Trypanosoma cruzi strain CL Brener
A0B8S9                 4 HKYYQL---SG--ETIKARKPICPR--CGNGVFLAEHED---RMSCGRCGYT 45  Methanothrix thermoacetophila PT
WP_013720493          15 SKYYEL---GG--DTIKSRKSVCPR--CGNGVFLADHGD---RQSCGKCGYT 56  Methanothrix soehngenii
CBRAS:FFONT_1334       5 HNYYEY---DYkTKTIKLKNKRCPR--C--GSIMGHYKEpteRWYCGSCGYT 49  Fervidicoccus fontis Kam940
WP_020448607          18 KNYYSV---NG--DKLERVKRNCPK--CGPGVFLAEHKD---RVSCGKCGYT 59  Candidatus Methanomassiliicoccus in...
WP_004077067           5 YKYYNV---EG--DRAEVQKKNCPR--CGPGVYMAEHGD---RVSCGKCGYT 46  Methanoplanus limicola
WP_013328056           6 YTYYKV---ED--DKAVTEKKHCPR--CGPGVFMAEHKD---RVSCGKCGYT 47  Methanolacinia
jgi:Maeo_0284         11 HNYYKV---EG--DKVEKLKKECPR--CKGGVFMAEHLN---RFACGKCGYT 52  Methanococcus aeolicus Nankai-3
P54031                10 YKYYKI---EG--DKVIRLKKTCPR--CGPGVFMAEHLN---RYACGKCGYM 51  Methanocaldococcus jannaschii DSM 2661
goetting:Ngar_c26980  15 YKFYKV---SG--DKVTRSRRDCPR--CGKGTFMAEHKD---RFTCGKCGFT 56  Candidatus Nitrososphaera gargensis...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap