4BTS,5XXU,7XNX


Conserved Protein Domain Family
Ribosomal_S27
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pfam01599: Ribosomal_S27 (This model is not part of the current CDD release)
Ribosomal protein S27a
This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesised as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilisation and is required for efficient ribosome biogenesis. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins.
Links
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Statistics
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PSSM-Id: 514377
Aligned: 55 rows
Threshold Bit Score: 42.5838
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4BTS_D9       97 ALAFYKLENnGKVSLQQKGCPKCGPGIFMAKHYDRHYCGKCHLT 140 Tetrahymena thermophila
A0B8S9         3 VHKYYQLSG-ETIKARKPICPRCGNGVFLAEHEDRMSCGRCGYT 45  Methanothrix thermoacetophila PT
5_pfamImport   1 VSKYYELGG-DTIKSRKSVCPRCGNGVFLADHGDRQSCGKCGYT 43 
WP_014587449   3 ANEFYDLAG-DAIKRKRQICPRCGNGVFLGEHKDRLACGKCGYT 45  Methanothrix harundinacea
4_pfamImport   1 VKEYYKVDG-DNIERTRQFCPRCGEGVFLAEHKDRLTCGKCGYT 43 
Q8TJT1         3 VKDYYKVQG-DSVTRLKQFCPRCGPGVFLADHKNRLACGKCGYT 45  Methanosarcina acetivorans C2A
WP_020448607  17 KKNYYSVNG-DKLERVKRNCPKCGPGVFLAEHKDRVSCGKCGYT 59  Candidatus Methanomassiliicoccus intestinalis
WP_004077067   4 RYKYYNVEG-DRAEVQKKNCPRCGPGVYMAEHGDRVSCGKCGYT 46  Methanoplanus limicola
WP_013328056   5 RYTYYKVED-DKAVTEKKHCPRCGPGVFMAEHKDRVSCGKCGYT 47  Methanolacinia
P54031         9 KYKYYKIEG-DKVIRLKKTCPRCGPGVFMAEHLNRYACGKCGYM 51  Methanocaldococcus jannaschii DSM 2661
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