6JZB,6PSI


Conserved Protein Domain Family
DnaJ_C

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pfam01556: DnaJ_C 
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DnaJ C terminal domain
This family consists of the C terminal region of the DnaJ protein. It is always found associated with pfam00226 and pfam00684. DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress. The two C-terminal domains CTDI and CTDII, both incorporated in this family are necessary for maintaining the J-domains in their specific relative positions. Structural analysis of PDB:1nlt shows that PF00684 is nested within this DnaJ C-terminal region.
Statistics
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PSSM-Id: 460251
Aligned: 960 rows
Threshold Bit Score: 72.2871
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6JZB_A       128 LQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGTSPVTCGRCHGAGVInvdtQTP----LGMMRRQVTCDVCHG 203
O85213       121 FIVNLKLSFKEAVFGCKKNIDFTYKCSCKTCNGTGAKDGKLQTCPKCQGRGQVG----VSQ----GFITFAQTCPDCQGI 192 Campylobacter j...
WP_013553430 121 LEVELELSFQEAVFGCEKEIDLQYKAPCDACRGTGAKDGQLQTCSTCGGQGQIV----MRQ----GFMTFAQECPHCQGR 192 Nitratifractor ...
XP_004365460 274 VRIGLEVSFMDAIDGTTKTIDFPTVTACTPCNGTGSSTGKTTRCPSCRGTGMET----VST----GMFAMQTTCRKCSGA 345
EQB65956     135 IRRIARNERIE--------VYYFREMKCEECDGTGSATKKLLTCPTCRGRGYVE----RSSnqgfILFRTTEVCRTCNGR 202
EQB72821     129 LLTNLRISLEDAYYGAKKTIKYRRNAECQTCHGTGSKDGKLVTCKDCNGTGQQR----VVQgqgfFRMVTVTTCKTCGGR 204
Q6L0S6       118 IYLRVNISLEDAYYGASKNVKYRRNAMCEHCSGTGAENKVLITCPTCHGSGQER----ITRgqgfFRMVTVTECRTCHGR 193 Picrophilus tor...
Q9HJ83       125 LYTNLDITLEDAYYGTEKRIKYRRNAMCPDCNGTGAKNGKLITCPTCNGTGQQR----IVRgqgfFRMVTVTTCQTCGGR 200 Thermoplasma ac...
EQB67206     122 LLTEISISMSEAYHGTVKSIKYRRTVPCEVCNGTGSKDGKVTTCPTCNGTGQQR----VVQgqgfFRMVSVTTCRTCNGK 197
THU48866     192 QVELNLSFSEAAKGCIKQVSFSAQVLCSSCHGRGHPVNAKPSRCPTCNGVGTVT----V--------FPFTSTCSSCRGL 259
6JZB_A       204 RGKEIKYPCTTCHGTGHEKQaH-SVHVKIPAGVETGQQIRLAGQGEagFNGGPYGDLYVVVSVeASDK-FEREGTTIFYN 281
O85213       193 GEKASEKCSDCKGLGYNESK-D-SVELNIPEGVDTGMKLRVNAKGNilKN-GTRGDMYVKIIAaEDDT-FIRDDDDIYIE 268 Campylobacter j...
WP_013553430 193 GQVVKEPCPECQGRSYQLKH-E-TVLLSIPAGVDTGNRLRIPAKGNedRN-GRRGDLYVLFYVeEDEH-FVREGNNLYIE 268 Nitratifractor ...
XP_004365460 346 GQVVQDPCKSCHGQGSVESH-R-KLDIKIPPGSDHNQSIRVPGAGEagTKGGATGDLWVVLQVgSH-PsLERQGPHIISQ 422
EQB65956     203 GKVPEKVCHVCSGSGFVRKK-D-KIEITPPAGINEDEIYILRGKGNf-RP-GGSGDLRIKFDI-DYME-FRREGDNLEKD 276
EQB72821     205 GKVPSVVCPDCHGTGSVPVT-E-NLEITVPKGAPDRLRLRIKGKGQshFG--RTGDLYVVLNVeETPG-MKRINDDIYIV 279
Q6L0S6       194 GKIPQKPCTVCHGTGTVSKN-E-DISVNIPKGADTNLKLRLKNMGNsyGG--VTGDLYIVLIVnNPPG-IRRSGQDIYVE 268 Picrophilus tor...
Q9HJ83       201 GRIPEEKCPRCNGTGTVVVN-E-DISVKIPKGATDNLRLRVQGKGQsyNG--RTGDLYVVLRVrNDRN-VQRINDDLMID 275 Thermoplasma ac...
EQB67206     198 GTVAKEACKACHGTGNKSIV-E-NIDVSIPKGAYDGLRLRVKGKGQthNN--RTGDLYVSIQVhSAPN-FRRSEDNLVTD 272
THU48866     260 GKIIKDHCSACRGLGVVDGV-KnVNVTIPAGVDSGDTISVPNVGNQggNGVHPGNLYIKLQVDkDPVF-LRDGSDVYVDT 337
6JZB_A       282 lnLNFVQ---AALGDTVDIptvhgdvELVIpegTQTGKKFRLRSKGAPSLR-GGAVGDQYVTVNVVTP 345
O85213       269 fpVFFTQ---AILGESIKVptirgeaTLNLpkgAKDGQRFVLEKEGVKDVH-SSRMGNQIVQISIKFP 332 Campylobacter jejuni subsp....
WP_013553430 269 vpVFFTQ---CVMGGEITIpsldgelELDLkpgTRDRAQFVFRGKGVPDVH-GGRTGDLIAQIKMILP 332 Nitratifractor salsuginis
XP_004365460 423 veIGLSQ---ALLGGTVPIqglrskfTLTIppkIADGTMLRMRRLGVKTE---DGQGDHLVSVRLKLP 484
EQB65956     277 idVDFID---AIIGGKVKVsllrgekEIDIpsgTQPGERIVLKGEGIQKKS-GKGNADVILRARVQLP 340
EQB72821     280 eeIGFPE---AALGVEKEIklfretlTFKIpagTQPGEVLRIKGAGFQHMN-GRGSGDVLVEIKVAVP 343
Q6L0S6       269 htIDFPE---AALGGEEEIklfresyNLKIpagTQPGEILKIKGAGMPRIN-GHGSGDLNVIIKIEVP 332 Picrophilus torridus DSM 9790
Q9HJ83       276 qkINFAQ---AALGDTIEVnlfrekySLKIpegTQPGEVLRIKGAGMPHLN-GHGSGDLLVRVNVEVP 339 Thermoplasma acidophilum DS...
EQB67206     273 meISFPD---AALGVENEIdvfgkkvTVKVpagTQPMDLVRVKGEGFQNVN-SGRNGDLVIRIRIAVP 336
THU48866     338 hiSFTQAmtaILGGDVEVPtlsgktkVKIPkgvQPGQLSILRGRGLPKQIGlVDHGDQYVRFRVHFPS 405
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