6U2A,2GU1,4RNY,8HD0,7QRL,5J1L,5KQB,2B13,3UZ0,6SMK,5B0H


Conserved Protein Domain Family
Peptidase_M23
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pfam01551: Peptidase_M23 (This model is not part of the current CDD release)
Peptidase family M23
Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.
Links
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Statistics
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PSSM-Id: 514345
Aligned: 237 rows
Threshold Bit Score: 42.5317
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6U2A_A 262 PHNGTDFAMPiGT--------PVYTSGDGVV--VMTR----Nh---------pYA-GNYVVIQH---GNT-YMTRYLHLS 313 Vibrio cholerae
O69910  86 GHRGVDLAAGgGA--------PVRAVAAGRV--SFAG----P-----------VGgRGVVSVELtgtGEPpLRTTFAP-- 138 Streptomyces coelicolor
Q82JX6 108 GHRGVDLAAApGT--------PVRSVAAGRV--SFAG----R-----------VAgRGVVSVELtgtGEPpLRTTYEP-- 160 Streptomyces avermitilis
Q8FP69  82 GHRGVDLPLAiGA--------DVLSAGDGVV--VFAG----M-----------VAgTPTISIDH---ADG-VRTTYQPVH 132 Corynebacterium effic...
Q8NP00  62 GHRGVDLPLNiGE--------TVLASGSGTV--AFAG----I-----------VVgTPTISIDH---ADG-VRTTYQPVH 112 Corynebacterium gluta...
Q8PD91 248 PHGGTDFNYEgGQqgrnlqhpTVHSPVSGTV--TFAG----G-----------NY-GTVKIHDA---QGN--SHEILHLD 304 Xanthomonas campestri...
Q21241  58 IIDGVDVRCHlGE--------PIYAPIEGEM--YFWR----Pyggk----rekSCaDQGVRIEG---TGQ-WQGYAVHIS 115 Caenorhabditis elegans
O14960  52 PHQGVDILCSaGS--------TVYAPFTGMI--VGQE----Kpyq------nkNAiNNGVRIS----GRG-FCVKMFYIK 106 human
Q81F05 149 SSKLEDYGIY-GA--------KVMAPASGTVvsINNN----EqdlvprsenfqSMaGNHIYLRVd--ETG-TFLILAHLK 212 Bacillus cereus ATCC ...
5B0H_B  36 PHQGVDVLCSaGS--------TVYAPFTGMI--VGQEkpyqNk---------nAI-NNGVRIS----GRG-FCVKMFYIK 90  human

6U2A_A 314 KIL--VK-KGQKVSRGQRIGLSG-NTGr---VT-------GPHLHYel-ivRGRPVN 355 Vibrio cholerae
O69910 139 -VDaaVR-KGDEVAAGEPLGTVQ-PTGsh-cTA---------CLHWgl-lrGEVYLN 181 Streptomyces coelicolor
Q82JX6 161 -VRpsVE-KGDEVAAGGSLGTLE-PTTahcsTA---------CLHWgl-lrGRTYLN 204 Streptomyces avermitilis
Q8FP69 133 Ah---VS-AGDPVVAKQAIGTLGhPT-----TA-------YPGLQWga-riGDDYIN 172 Corynebacterium efficiens
Q8NP00 113 Ah---VS-VGEHVEEGDAIGILGhPT-----TK-------FPGLQWga-kiGEEYIN 152 Corynebacterium glutamicum
Q8PD91 305 ALK--VK-EGQTLSAGDAIGTMG-GLGp--nGNsq----yAQHVHYqlrdaNGKLTS 351 Xanthomonas campestris pv. campestris
Q21241 116 SVK--LSfFGGHVEAGDEIGEAL-NRYc---FNdrgqndvEPHVEIrl-ykEGRLID 165 Caenorhabditis elegans
O14960 107 P----IK-YKGPIKKGEKLGTLL-PLQk---VYpg----iQSHVHIe----NCDSSD 146 human
Q81F05 213 KGSinVR-EGQHVNEGEFLAQVGnSGS----SS-------EPHLHI-----HHQRQD 252 Bacillus cereus ATCC 14579
5B0H_B  91 PI----K-YKGPIKKGEKLGTLL-PLQk---VYpg----iQSHVHIe----NCDSSD 130 human
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